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Other CD2 Family entries

IMGT RPI entry from gene to protein for Mus musculus CD2

Citing IMGT RPI entry for CD2

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

CD2 Gene exon/intron organization

Legend:

Number of alleles: 4

IMGT reference alleles

Allele names Gene functionality Strain IMGT reference sequences
Exons Accession numbers Molecule type
CD2*01 F BALB/c EX1-5 M19799, M19801, M19803, M19805, M19807 [1] gDNA
CD2*02 F EX1-5 M18934 [2] cDNA (1)
CD2*03 F EX1-5 AL672260 gDNA (2)
CD2*04 F EX1-5 X06143 [3] cDNA (3)

IMGT reference sequences (in FASTA format) for the allele(s): CD2*01 to CD2*04

Other sequences from the literature

Allele names Gene functionality Strain IMGT reference sequences
Exons Accession numbers Molecule type
CD2*01 F BALB/c EX1-5 AF065909 cDNA
BALB/cByJ EX1-5 AF306543
DBA/2J EX1-5 AF065906
CD2*03 F NOD/LtJ EX1-5 AF065907 cDNA
RIIIS/J EX1-5 AF065908
C57BL/6NCrl EX1-5 BC053731
B10.A EX1-5 Y00023
EX1-5 NM_013486

Corresponding protein database accession numbers

Allele names Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
CD2*01 M19799, M19801, M19803, M19805, M19807 P08920 344 aa 1
CD2*02 M18934 (1) 344 aa 1
CD2*03 AL672260 Q5SRC1 344 aa 1
NM_013486 NP_038514 344 aa 1
CD2*04 X06143 (3) 344 aa 1
IMGT notes:
  1. (1) EX3[D2] c65>g; T22>L in C-LIKE-DOMAIN, numbering according to unique numbering for C-DOMAIN and C-LIKE-DOMAIN
  2. (2) EX3[D2] g20>a; V7>M, a145>g, g296>a; S99>N and c360>t; T120>M in C-LIKE-DOMAIN, numbering according to unique numbering for C-DOMAIN and C-LIKE-DOMAIN
  3. (3) EX3[D2] g20>a; V7>M, a145>g, g296>a; S99>N and g358>t, c360>t; T120>M in C-LIKE-DOMAIN, numbering according to unique numbering for C-DOMAIN and C-LIKE-DOMAIN
IMGT references:
  1. [1] Diamond D.J. et al, Proc. Natl. Acad. Sci. U.S.A. 85, 1615-1619 (1988). PMID: 2894031
  2. [2] Yagita H. et al, J. Immunol. 140, 1321-1326 (1988). PMID: 3257775
  3. [3] Clayton L.K. et al, Eur. J. Immunol. 17, 1367-1370 (1987). PMID: 2820751

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

CD2*01: M19799(g) M19801(g) M19803(g) M19805(g) M19807(g)

Nucleotide sequence

1        atgaaatgta aattcctggg tagcttcttt ctgctcttca gcctttccgg caaaggggcg

61       gactgcagag acaatgagac catctggggt gtcttgggtc atggcatcac cctgaacatc

121      cccaactttc aaatgactga tgatattgat gaggtgcgat gggtaaggag gggcaccctg

181      gtcgcagagt ttaaaaggaa gaagccacct tttttgatat cagaaacgta tgaggtctta

241      gcaaacggat ccctgaagat aaagaagccg atgatgagaa acgacagtgg cacctataat

301      gtaatggtgt atggcacaaa tgggatgact aggctggaga aggacctgga cgtgaggatt

361      ctggagaggg tctcaaagcc cgtgatccac tgggaatgcc ccaacacaac cctgacctgt

421      gcggtcttgc aaggaacaga ttttgaactg aagctgtatc aaggggaaac actactcaat

481      agtctccccc agaagaacat gagttaccag tggaccaacc tgagcgcacc attcaagtgt

541      gaggcgataa acccggtcag caaggagtct aagacggaag ttgttaactg tccagagaaa

601      ggtctgtcct tctatgtcac agtgggggtc ggtgcaggag gactcctctt ggtgctcttg

661      gtggcgcttt ttattttctg tatctgcaag aggagaaaac ggaacaggag gagaaaagat

721      gaagagctgg aaataaaagc ttccagaaca agcactgtgg aaaggggccc caagccgcac

781      tcaaccccag ccgcagcagc gcagaattca gtggcgctcc aagctcctcc tccacctggc

841      catcacctcc agacacctgg ccatcgtccc ttgcctccag gccaccgtac ccgtgagcac

901      cagcagaaga agagacctcc tccatcaggc acacagattc accagcagaa aggccctcct

961      ttacccagac cccgagttca gccaaaacct ccctgtggga gtggagatgg tgtttcactg

1021     ccgcccccta attaa
Nucleotide sequence in FASTA format (without gaps) CD2*01

Amino acid sequence

1        MKCKFLGSFF LLFSLSGKGA DCRDNETIWG VLGHGITLNI PNFQMTDDID EVRWVRRGTL

61       VAEFKRKKPP FLISETYEVL ANGSLKIKKP MMRNDSGTYN VMVYGTNGMT RLEKDLDVRI

121      LERVSKPVIH WECPNTTLTC AVLQGTDFEL KLYQGETLLN SLPQKNMSYQ WTNLSAPFKC

181      EAINPVSKES KTEVVNCPEK GLSFYVTVGV GAGGLLLVLL VALFIFCICK RRKRNRRRKD

241      EELEIKASRT STVERGPKPH STPAAAAQNS VALQAPPPPG HHLQTPGHRP LPPGHRTREH

301      QQKKRPPPSG TQIHQQKGPP LPRPRVQPKP PCGSGDGVSL PPPN*
Amino acid sequence in FASTA format (without gap) CD2*01

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