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IMGT RPI entry from gene to protein for Mus musculus CD28

Citing IMGT RPI entry for CD28

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

CD28 Gene exon/intron organization

Legend:

Number of alleles: 1

IMGT reference alleles

Allele names Gene functionality IMGT reference sequences
Clone names Exons Accession numbers Molecule type
CD28*01 F EX1-4 AL672024 gDNA

IMGT reference sequences (in FASTA format) for the allele(s): CD28*01

Other sequences from the literature

Allele names Gene functionality IMGT reference sequences
Clone names Exons Accession numbers Molecule type
CD28*01 F RP23-157N11 EX1-4 AL646054 gDNA
DN-378G17 EX1-4 M34563[1] cDNA(1)
5830411K06 EX1-4 AK030812 cDNA
MGC:73611 EX1-4 BC064058
EX1-4 NM_007642

Corresponding protein database accession numbers

Allele names Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
CD28*01 AL672024 P09693 218 aa 1
NM_007642 NP_031668 218 aa 1
CD28*02 M34563 P31041 218 aa 1
IMGT notes:
  1. (1) In EX4, sequence from 34-41[agtgacta]>[gtgactac], 12-14[SDY]>[VTT].
IMGT references:
  1. [1] Gross, J.A., St John, T. and Allison, J.P. Journal of Immunology 144, 3201-3210 (1990). PMID: 2157764

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

CD28*01: AL672024(g)

Nucleotide sequence

1        atgacactca ggctgctgtt cttggctctc aacttcttct cagttcaagt aacagaaaac

61       aagattttgg taaagcagtc gcccctgctt gtggtagata gcaacgaggt cagcctcagc

121      tgcaggtatt cctacaacct tctcgcaaag gaattccggg catccctgta caagggcgtg

181      aacagcgacg tggaagtctg tgtcgggaat gggaatttta cctatcagcc ccagtttcgc

241      tcgaatgccg agttcaactg cgacggggat ttcgacaacg aaacagtgac gttccgtctc

301      tggaatctgc acgtcaatca cacagatatt tacttctgca aaattgagtt catgtaccct

361      ccgccttacc tagacaacga gaggagcaat ggaactatta ttcacataaa agagaaacat

421      ctttgtcata ctcagtcatc tcctaagctg ttttgggcac tggtcgtggt tgctggagtc

481      ctgttttgtt atggcttgct agtgacagtg gctctttgtg ttatctggac aaatagtaga

541      aggaacagac tccttcaaag tgactacatg aacatgactc cccggaggcc tgggctcact

601      cgaaagcctt accagcccta cgcccctgcc agagactttg cagcgtaccg cccctga
Nucleotide sequence in FASTA format (without gaps) CD28*01

Amino acid sequence

1        MTLRLLFLAL NFFSVQVTEN KILVKQSPLL VVDSNEVSLS CRYSYNLLAK EFRASLYKGV

61       NSDVEVCVGN GNFTYQPQFR SNAEFNCDGD FDNETVTFRL WNLHVNHTDI YFCKIEFMYP

121      PPYLDNERSN GTIIHIKEKH LCHTQSSPKL FWALVVVAGV LFCYGLLVTV ALCVIWTNSR

181      RNRLLQSDYM NMTPRRPGLT RKPYQPYAPA RDFAAYRP*
Amino acid sequence in FASTA format (without gap) CD28*01

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