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Other CD3 entries

IMGT RPI entry from gene to protein for Mus musculus CD3D

Citing IMGT RPI entry for CD3D

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

CD3D Gene exon/intron organization

Legend:

Number of alleles: 4

IMGT reference alleles

Allele names Gene functionality Strain IMGT reference sequences
Clone names Exons Accession numbers Molecule type
CD3D*01 F pMT-2 EX1 M12728 [1] gDNA
EX2-EX5 M12729 gDNA
CD3D*02 F C57BL/6J MGC:73593 EX1-EX5 BC062807 cDNA (1)
CD3D*03 F C57BL/6J A630066F16 EX1-EX5 AK042172 cDNA (2)
CD3D*04 F C57BL/6J C920019G15 EX1-EX5 AK153843 cDNA (3)

IMGT reference sequences (in FASTA format) for the allele(s): CD3D*01 to CD3D*04

Other sequences from the literature

Allele names Gene functionality Strain IMGT reference sequences
Clone names Exons Accession numbers Molecule type
CD3D*01 F EX1-EX5 X02339 gDNA
C57BL/6J C920024P13 AK050629 cDNA
NOD E430031K17 AK154064 cDNA
BALB/c pKR-1 EX1 M18222 gDNA
CD3D*02 F EX1-EX5 NM_013487 cDNA

Corresponding protein database accession numbers

Allele names Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
CD3D*01 M12728-M12729 P04235 173 aa 1
CD3D*02 BC062807 Tr:Q6P5P1 173 aa 1
NM_013487 NP_038515 173 aa 1
CD3D*03 AK042172 Tr:Q3V3B4 173 aa 1
CD3D*04 AK153843 Tr:Q3U572 173 aa 1
IMGT notes:
  1. (1) In EX2[D] a22>g; I8>V, positions according to the IMGT unique numbering for C-DOMAIN and C-LIKE DOMAIN.
  2. (2) In EX5 g41>a; G14>E.
  3. (3) In EX5 c68>t; S23>F.
IMGT references:
  1. [1] van den Elsen, P.et al, Proc. Natl. Acad. Sci. U.S.A. 83, 2944-2948 (1986) . PMID: 2939461

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

CD3D*01: M12728(g) M12729(g)

Nucleotide sequence

1        atggaacaca gcgggattct ggctagtctg atactgattg ctgttctccc ccaagggagc

61       cccttcaaga tacaagtgac cgaatatgag gacaaagtat ttgtgacctg caataccagc

121      gtcatgcatc tagatggaac ggtggaagga tggtttgcaa agaataaaac actcaacttg

181      ggcaaaggcg ttctggaccc acgagggata tatctgtgta atgggacaga gcagctggca

241      aaggtggtgt cttctgtgca agtccattac cgaatgtgcc agaactgtgt ggagctagac

301      tcgggcacca tggctggtgt catcttcatt gacctcatcg caactctgct cctggctttg

361      ggcgtctact gctttgcagg acatgagacc ggaaggcctt ctggggctgc tgaggttcaa

421      gcactgctga agaatgagca gctgtatcag cctcttcgag atcgtgaaga tacccagtac

481      agccgtcttg gagggaactg gccccggaac aagaaatctt aa
Nucleotide sequence in FASTA format (without gaps) CD3D*01

Amino acid sequence

1        MEHSGILASL ILIAVLPQGS PFKIQVTEYE DKVFVTCNTS VMHLDGTVEG WFAKNKTLNL

61       GKGVLDPRGI YLCNGTEQLA KVVSSVQVHY RMCQNCVELD SGTMAGVIFI DLIATLLLAL

121      GVYCFAGHET GRPSGAAEVQ ALLKNEQLYQ PLRDREDTQY SRLGGNWPRN KKS*
Amino acid sequence in FASTA format (without gap) CD3D*01

Legend: