Here you are: IMGT Web resources > IMGT Repertoire (RPI) > RPI entries from gene to protein
Other CD8A entries

IMGT RPI entry from gene to protein for Mus musculus CD8A

Citing IMGT RPI entry for CD8A

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

CD8A Gene exon/intron organization

Legend:

Number of alleles: 8

IMGT reference alleles

Allele names Gene functionality Strain IMGT reference sequences
Exons Accession numbers Molecule type
CD8A*01 F EX1-5 M22064 [1] gDNA
CD8A*02 EX1 M12819 [2] gDNA (1)
EX2-3 M12975
EX4 M12976
EX5 M12977
CD8A*03 B10.A EX1-5 Y00157 [2] gDNA (2)
CD8A*04 EX1 M12978 [3] gDNA (3) partial
EX2-3 M12979
CD8A*05 NOD EX1-5 AK088128 cDNA (4)
CD8A*06 NOD EX1-5 U34881 [4] cDNA (5)
CD8A*07 NOD EX1-5 AK088214 cDNA (6)
CD8A*08 NOD EX1-3, 6 AK088414 cDNA (7) splicing B

IMGT reference sequences (in FASTA format) for the allele(s): CD8A*01 to CD8A*08

Other sequences from the literature

Allele names Gene functionality Strain IMGT reference sequences
Exons Accession numbers Molecule type
CD8A*02 F BALB/c EX1-5 M12825 cDNA
EX1-5 M12052
C57BL/6J EX1-5 AK137937 cDNA partial
EX1-3, 6 AK037467 cDNA splicing B
EX1-5 XM_132621 cDNA
CD8A*03 C57BL/6J EX1-5 M16981 cDNA
CD8A*05 C57BL/6J EX1-3, 6 BC030679 cDNA splicing B

Corresponding protein database accession numbers

Allele names Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
CD8A*01 M22064 247 aa 1
CD8A*02 M12819 P01731 247 aa 1
M12975 247 aa 1
M12976 247 aa 1
M12977 247 aa 1
XM_132621 XP_132621 247 aa 1
CD8A*03 Y00157 246 aa 1
CD8A*04 M12978 Q61816 220 aa 1 partial
M12979 220 aa 1 partial
CD8A*05 AK088128 Tr:Q542K6 247 aa 1
CD8A*06 U34881 Tr:Q60965 247 aa 1
CD8A*07 AK088214 Tr:Q8C2Q0 247 aa 1
CD8A*08 AK088414 Tr:Q8C2L1 222 aa 2
IMGT notes:
  1. (1) In EX1 c48>t (L-REGION) and g241>a; V81>M, numbering according to IMGT unique numbering for V-DOMAIN and V-LIKE-DOMAIN. In EX3 c71>t; P24>L.
  2. (2) In EX1 c48>t (L-REGION), codon (157gtc159>del#; V53>del#), this deletion may be a sequence error and g241>a; V81>M, numbering according to IMGT unique numbering for V-DOMAIN and V-LIKE-DOMAIN. In EX3 c71>t; P24>L.
  3. (3) In EX1 t60>g; I20>M (L-REGION) and in EX3 c47>t; A16>V and c71>t; P24>L.
  4. (4) In EX3 c71>t; P24>L (L-REGION).
  5. (5) In EX1 c46>a; L15>M (L-REGION).
  6. (6) In EX1 c6>g and t62>c; L21>P (L-REGION) and in EX3 c71>t; P24>L.
  7. (7) Splicing B (222 aa). Utilize a novel exon EX6 (8 nt). In EX1 t38>c; L13>P (L-REGION), 291a>g, numbering according to IMGT unique numbering for V-DOMAIN and V-LIKE-DOMAIN. In EX3 c71>t; P24>L.
IMGT references:
  1. [1] Youn.H.J, Harriss.J.V. and Gottlieb.P.D., Immunogenetics 28, 345-352 (1988). PMID: 3267233
  2. [2] Nakauchi.H. et al, Nucleic Acids Research, 15, 4337-4347 (1987). PMID: 3495785
  3. [3] Liaw.C.W, Zamoyska.R and Parnes.J.R, The Journal of Immunology 137, 1037-1043 (1986). PMID: 3487583
  4. [4] Johnson-Tardieu.J.M. et al, Immunogenetics 43, 6-12 (1996). PMID: 8537123

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

CD8A*01: M22064(g)

Nucleotide sequence

1        atggcctcac cgttgacccg ctttctgtcg ctgaacctgc tgctgctggg tgagtcgatt

61       atcctgggga gtggagaagc taagccacag gcacccgaac tccgaatctt tccaaagaaa

121      atggacgccg aacttggcca gaaggtggac ctggtatgtg aagtgttggg gtccgtttcg

181      caaggatgct cttggctctt ccagaactcc agctccaaac tcccccagcc caccttcgtt

241      gtctatatgg cttcatccca caacaagata acgtgggacg agaagctgaa ttcgtcgaaa

301      ctgttttctg ccgtgaggga cacgaataat aagtacgttc tcaccctgaa caagttcagc

361      aaggaaaacg aaggctacta tttctgctca gtcatcagca actcggtgat gtacttcagt

421      tctgtcgtgc cagtccttca gaaagtgaac tctactacta ccaagccagt gctgcgaact

481      ccctcacctg tgcaccctac cgggacatct cagccccaga gaccagaaga ttgtcggccc

541      cgtggctcag tgaaggggac cggattggac ttcgcctgtg atatttacat ctgggcaccc

601      ttggccggaa tctgcgtggc ccctctgctg tccttgatca tcactctcat ctgctaccac

661      aggagccgaa agcgtgtttg caaatgtccc aggccgctag tcagacagga aggcaagccc

721      agaccttcag agaaaattgt gtaa
Nucleotide sequence in FASTA format (without gaps) CD8A*01

Amino acid sequence

1        MASPLTRFLS LNLLLLGESI ILGSGEAKPQ APELRIFPKK MDAELGQKVD LVCEVLGSVS

61       QGCSWLFQNS SSKLPQPTFV VYMASSHNKI TWDEKLNSSK LFSAVRDTNN KYVLTLNKFS

121      KENEGYYFCS VISNSVMYFS SVVPVLQKVN STTTKPVLRT PSPVHPTGTS QPQRPEDCRP

181      RGSVKGTGLD FACDIYIWAP LAGICVAPLL SLIITLICYH RSRKRVCKCP RPLVRQEGKP

241      RPSEKIV*
Amino acid sequence in FASTA format (without gap) CD8A*01

Legend: