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Other CD8B entries

IMGT RPI entry from gene to protein for Mus musculus CD8B

Citing IMGT RPI entry for CD8B

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

CD8B Gene exon/intron organization

Legend:

Number of alleles: 3

IMGT reference alleles

Allele names Gene functionality Strain IMGT reference sequences
Exons Accession numbers Molecule type
CD8B*01 F B10.A EX1 M26441 [1] gDNA
EX2 M26442
EX3 M26443
EX4 M26444
EX5 M26445
EX6 M26446
CD8B*02 F C.AKR EX1 M22065 [2] gDNA (2)
EX2 M22066
EX3 M22067
EX4 M22068
EX5 M22069
EX6 M22070
CD8B*03 F NOD EX1-6 AK087944 cDNA (3)

IMGT reference sequences (in FASTA format) for the allele(s): CD8B*01 to CD8B*03

Other sequences from the literature

Allele names Gene functionality Strain IMGT reference sequences
Exons Accession numbers Molecule type
CD8B*01 F BALB/c EX1-6 M16799 cDNA
EX1-6 M17534
EX1-6 M19504
C57BL/6J EX1-6 AK162993
EX1-6 AK169581
EX1-6 X07698
EX1-6 NM_009858
CD8B*02 NOD EX1-6 AK088372 cDNA
EX1-6 AK088649
EX1-6 AK154055
EX1-2, 5-6 U34882 cDNA (4) splicing B

Corresponding protein database accession numbers

Allele names Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
CD8B*01 M26441 P10300 213 aa 1
M26442 213 aa 1
M26443 213 aa 1
M26444 213 aa 1
M26445 213 aa 1
M26446 213 aa 1
NM_009858 NP_033988 213 aa 1
CD8B*02 M22065 213 aa 1
M22066 213 aa 1
M22067 213 aa 1
M22068 213 aa 1
M22069 213 aa 1
M22070 213 aa 1
CD8B*03 AK087944 213 aa 1
IMGT notes:
  1. (1) In EX2[D] a225>c; R85>S, positiions according to IMGT unique numbering for V-DOMAIN and V-LIKE-DOMAIN.
  2. (2) In EX2[D] a225>c; R85>S, positiions according to IMGT unique numbering for V-DOMAIN and V-LIKE-DOMAIN. In EX3 a58>c; K20>N.
  3. (3) Splicing B (134 aa). This transcript has an inframe-splice site in EX2 3' region 45 bp up-stream to the normal splice site and in EX5 5' region 9 bp down-stream to the normal splice site. No EX3-4.
IMGT references:
  1. [1] Nakayama K. et al, J. Immunol. 142, 2540-2546 (1989). PMID: 2784466
  2. [2] Youn H.J. Harriss J.V. and Gottlieb P.D. Immunogenetics 28, 353-361 (1988). PMID: 3169881

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

CD8B*01: M26441(g) M26442(g) M26443(g) M26444(g) M26445(g) M26446(g)

Nucleotide sequence

1        atgcagccat ggctctggct ggtcttcagt atgaagctgg cagctctctg gagcagctct

61       gccctcattc agaccccttc gtccctgctg gttcaaacca accatacggc aaagatgtcc

121      tgtgaggtta aaagcatctc taagttaaca agcatctact ggctgcggga gcgccaggac

181      cccaaggaca agtactttga gttcctggcc tcctggagtt cttccaaagg agttttgtat

241      ggtgaaagtg tggacaagaa aagaaatata attcttgagt cttcagactc aagacggccc

301      tttctcagta tcatgaatgt gaagccagag gacagtgact tctacttctg cgcgacggtt

361      gggagcccca agatggtctt tgggacaggg acgaagctga ctgtggttga tgtccttcct

421      acaactgccc caaccaagaa gactaccctg aagatgaaga agaagaagca atgcccgttc

481      ccccacccag agacccagaa gggcctgaca tgcagcctta ccaccctcag cctgctggta

541      gtctgcatcc tgcttctgct ggcattcctc ggagtggccg tctactttta ctgtgtgcgg

601      aggagagccc gaattcactt catgaaacag tttcacaaat ga
Nucleotide sequence in FASTA format (without gaps) CD8B*01

Amino acid sequence

1        MQPWLWLVFS MKLAALWSSS ALIQTPSSLL VQTNHTAKMS CEVKSISKLT SIYWLRERQD

61       PKDKYFEFLA SWSSSKGVLY GESVDKKRNI ILESSDSRRP FLSIMNVKPE DSDFYFCATV

121      GSPKMVFGTG TKLTVVDVLP TTAPTKKTTL KMKKKKQCPF PHPETQKGLT CSLTTLSLLV

181      VCILLLLAFL GVAVYFYCVR RRARIHFMKQ FHK*
Amino acid sequence in FASTA format (without gap) CD8B*01

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