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IMGT RPI entry from gene to protein for Mus musculus CTLA4

Citing IMGT RPI entry for CTLA4

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004) pdf with permission from Research Signpost

IMGT gene name and definition

Chromosomal localization

Gene exon/intron organization

CTLA4 Gene exon/intron organization

Legend:

Number of alleles: 3

IMGT reference alleles

Allele names Gene functionality IMGT reference sequences
Clone Exons Accession numbers Molecule type
CTLA4*01 F EX1-4 AF142145 [1] gDNA
CTLA4*02 F EX1-4 X05719 [2] cDNA (1)
CTLA4*03 F MGC:60618 EX1-4 BC052683 [3] cDNA (2)

IMGT reference sequences (in FASTA format) for the allele(s): CTLA4*01 to CTLA4*03

Other sequences from the literature

Allele names Gene functionality IMGT reference sequences
Clones Exons Accession numbers Molecule type
CTLA4*01 F RP23-146J17 EX1-4 AL663047 gDNA
MGC:51581 EX1-4 BC042741 cDNA
EX1-4 NM_009843

Corresponding protein database accession numbers

Allele names Accession numbers Number of amino acids Protein isoform
Nucleotide databases Protein databases
CTLA4*01 AF142145 223 aa 1
NM_009843 NP_005205 223 aa 1
CTLA4*02 X05719 P09793 223 aa 1
CTLA4*03 BC052683 223 aa 1
IMGT notes:
  1. (1) In EX4 a87>t,T29>S.
  2. (2) EX2[D] a369>g, Q123>R, numbering according to IMGT unique numbering for V-DOMAIN and V-LIKE-DOMAIN.
IMGT references:
  1. [1] Ling,V., et al. Genomics 60, 341-355 (1999). PMID: 10493833
  2. [2] Brunet,J.F.,Golsten P et al. Nature 328, 267-270 (1987) . PMID: 3496540
  3. [3] Strausberg,R.L, et al. Proc. Natl. Acad. Sci. U.S.A. 99, 16899-16903 (2002). PMID: 12477932

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

CTLA4*01: AF142145(g)

Nucleotide sequence

1        atggcttgtc ttggactccg gaggtacaaa gctcaactgc agctgccttc taggacttgg

61       ccttttgtag ccctgctcac tcttcttttc atcccagtct tctctgaagc catacaggtg

121      acccaacctt cagtggtgtt ggctagcagc catggtgtcg ccagctttcc atgtgaatat

181      tcaccatcac acaacactga tgaggtccgg gtgactgtgc tgcggcagac aaatgaccaa

241      atgactgagg tctgtgccac gacattcaca gagaagaata cagtgggctt cctagattac

301      cccttctgca gtggtacctt taatgaaagc agagtgaacc tcaccatcca aggactgaga

361      gctgttgaca cgggactgta cctctgcaag gtggaactca tgtacccacc gccatacttt

421      gtgggcatgg gcaacgggac gcagatttat gtcattgatc cagaaccatg cccggattct

481      gacttcctcc tttggatcct tgtcgcagtt agcttggggt tgttttttta cagtttcctg

541      gtcactgctg tttctttgag caagatgcta aagaaaagaa gtcctcttac aacaggggtc

601      tatgtgaaaa tgcccccaac agagccagaa tgtgaaaagc aatttcagcc ttattttatt

661      cccatcaact ga
Nucleotide sequence in FASTA format (without gaps) CTLA4*01

Amino acid sequence

1        MACLGLRRYK AQLQLPSRTW PFVALLTLLF IPVFSEAIQV TQPSVVLASS HGVASFPCEY

61       SPSHNTDEVR VTVLRQTNDQ MTEVCATTFT EKNTVGFLDY PFCSGTFNES RVNLTIQGLR

121      AVDTGLYLCK VELMYPPPYF VGMGNGTQIY VIDPEPCPDS DFLLWILVAV SLGLFFYSFL

181      VTAVSLSKML KKRSPLTTGV YVKMPPTEPE CEKQFQPYFI PIN*
Amino acid sequence in FASTA format (without gap) CTLA4*01

Legend: