Human (Homo sapiens) IGK locus at 2p11.2

• The human IGK locus is located on the short arm of chromosome 2 at 2p11.2

• The human IGK locus is in reverse orientation: being located on the short arm, the 5' end of the locus is centromeric and the 3' end is telomeric.

• In IMGT/GeneSearch, IMGT/GeneView and IMGT/LocusView:



• The IGK locus localization (start and end: 39007-1717793 bp) and the gene positions are those in the clone contig which starts at the position 39007 of AP001214 and ends at the position 1717793 of AP001215.


• The proximal V-CLUSTER (close to IGKC) and the distal V-CLUSTER are separated by ~800 kb.
  The proximal V-CLUSTER is situated between position 1200000 and 1800000, and the distal V-CLUSTER is situated between position 0 and 600000.




• Clones (in blue) are those used for the complete sequencing of the human IGK locus.


• IMGT reference sequences clones and accession numbers are available in IMGT/GENE-DB and in Gene tables  (IMGT Repertoire).


• Number of genes in the IMGT genome analysis tools

• Particularities of the pseudogene delimitations:
  
  
  • IGKV2D-19, IGKV2D-38, IGKV2-19: the 5' limit is that of the V-REGION, there is no L-PART1 and no L-PART2.
  
  
  
  • IGKV2-36, IGKV2D-36: the 5' limit is that of the V-REGION, there is no L-PART1 and no L-PART2. the 3' limit is that of the V-REGION, there is no V-RS (no V-NONAMER, no V-SPACER and no V-HEPTAMER).
  
  
  
  • IGKV2D-23: the 3' limit is that of the V-HEPTAMER, there is no V-SPACER and no V-NONAMER.
  
  
  

See also:

-> IMGT/GeneSearch, IMGT/GeneView, IMGT/LocusView and IMGT/CloneSearch Documentation
-> IMGT/GeneSearch, IMGT/GeneView, IMGT/LocusView and IMGT/CloneSearch Query page

Contact: Marie-Paule Lefranc

Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.

For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

IMGT Repertoire (IG and TR)
IMGT Repertoire (MHC)
IMGT Repertoire (RPI)
IMGT Index
IMGT Scientific chart
IMGT Education
IMGT Home page

IMGT founder and director: Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr Bioinformatics manager: Véronique Giudicelli Veronique.Giudicelli@igh.cnrs.fr Computer manager: Patrice Duroux Patrice.Duroux@igh.cnrs.fr Webmaster: Chantal Ginestoux Chantal.Ginestoux@igh.cnrs.fr
Citing IMGT Warranty disclaimer and copyright notice Privacy policy and advertisement policy © Copyright 1995-2010 IMGT®, the international ImMunoGeneTics information system®