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Today is Thursday, May 24 2012
Database contains 395 entries
249 -mab
18 -cept

IMGT/mAb-DB Query page

Version:: 1.3.1 (14/12/2011)
Database release:: 201217-2 (24/04/2012)

Citing IMGT/mAb-DB:: Poiron, C. et al., JOBIM 2010, Paper 13 (2010). Abstract

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IMGT/mAb-DB ID

INN (International Nonproprietary Name)

INN number

Common name

INN proposed list: and before and after

INN recommended list: and before and after

Proprietary name

Species

IMGT receptor type: any; IG; FPIA; CPCA; RPI; none

IG class and subclass (for complete IG)

Radiolabelled with

Origin clone species

Origin clone name

IG format (for IG fragments or constructs)

Conjugated with

Entries in IMGT/2Dstructure-DB

Entries in IMGT/3Dstructure-DB

FPIA chain identification

Radiolabelled with

Origin clone species

Origin clone name

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Entries in IMGT/2Dstructure-DB

Entries in IMGT/3Dstructure-DB

RPI chain identification

Radiolabelled with

Origin clone species

Origin clone name

Conjugated with

Entries in IMGT/2Dstructure-DB

Entries in IMGT/3Dstructure-DB

CPCA chain identification

Origin clone species

Origin clone name

Entries in IMGT/2Dstructure-DB

Entries in IMGT/3Dstructure-DB

IG class and subclass (for complete IG)

IG format (for IG fragments or constructs)

FPIA chain identification

CPCA chain identification

RPI chain identification

Radiolabelled with

Origin clone species

Origin clone name

Conjugated with

Entries in IMGT/2Dstructure-DB

Entries in IMGT/3Dstructure-DB

Radiolabelled with

Origin clone species

Origin clone name

Conjugated with

Entries in IMGT/2Dstructure-DB

Entries in IMGT/3Dstructure-DB

Specificity target name

Specificity target species

Clinical indication

Clinical domain

Application

Expression system

Company

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Regulatory decision year

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Created:: 03/04/2009
Database development:: Yan Wu, Patrice Duroux and Claire Poiron
Database scientific officer:: Marie-Paule Lefranc

Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

IMGT founder and director:: Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr
Bioinformatics manager:: Véronique Giudicelli Veronique.Giudicelli@igh.cnrs.fr
Computer manager:: Patrice Duroux Patrice.Duroux@igh.cnrs.fr
Webmaster:: Chantal Ginestoux Chantal.Ginestoux@igh.cnrs.fr

-
any
none
IgA nd
IgE nd
IgG kappa
IgG nd
IgG1 kappa
IgG1 lambda
IgG1 nd
IgG2 kappa
IgG2 nd
IgG2a kappa
IgG2a lambda
IgG2a nd
IgG2b kappa
IgG2b nd
IgG3 kappa
IgG3 nd
IgG4 kappa
IgG4 lambda
IgG4 nd
IgM kappa
IgM nd

-
any
none
F(ab') 2 - G1 nd
F(ab')2
F(ab')2 - G1 nd
F(ab')2, Fab/Fab2 mix
Fab
Fab - G1 kappa
Fab - G2a kappa
Fab - G2b kappa
Fab - G4 nd
Fab'
Fab' - G nd
Fab' - G1 kappa
Fab' - G1 nd
Fab' - G2a kappa
Fab' - G2a nd
Fab/Fc - IgG1 kappa
Fv , disulfide stabilized
IgG1 kappa / F(ab')2
IgG2/G4 kappa
IgG2a kappa / G2b lambda
IgG2a nd / G2b nd
scFv
scFv - CH dimer
scFv-Fc
scFv-scFv
VH - linker - VH
VH-VH'-VH

-
any
none
IgA nd
IgE nd
IgG kappa
IgG nd
IgG1 kappa
IgG1 lambda
IgG1 nd
IgG2 kappa
IgG2 nd
IgG2a kappa
IgG2a lambda
IgG2a nd
IgG2b kappa
IgG2b nd
IgG3 kappa
IgG3 nd
IgG4 kappa
IgG4 lambda
IgG4 nd
IgM kappa
IgM nd

-
any
none
F(ab') 2 - G1 nd
F(ab')2
F(ab')2 - G1 nd
F(ab')2, Fab/Fab2 mix
Fab
Fab - G1 kappa
Fab - G2a kappa
Fab - G2b kappa
Fab - G4 nd
Fab'
Fab' - G nd
Fab' - G1 kappa
Fab' - G1 nd
Fab' - G2a kappa
Fab' - G2a nd
Fab/Fc - IgG1 kappa
Fv , disulfide stabilized
IgG1 kappa / F(ab')2
IgG2/G4 kappa
IgG2a kappa / G2b lambda
IgG2a nd / G2b nd
scFv
scFv - CH dimer
scFv-Fc
scFv-scFv
VH - linker - VH
VH-VH'-VH

any
none
Activin A
adenocarcinoma antigen
AFP (alpha-fetoprotein)
ALB (albumin, human serum albumin, HSA)
ALPP (alkaline phosphatase, placental, EC 3.1.3.1)
amyloid beta (Abeta)
amyloid beta (Abeta) peptide Aβ40
amyloid beta (Abeta) peptide soluble monomer
amyloid beta (Abeta) peptides Aβ42 and Aβ40
ANGPT2 (Ang2, angiopoietin 2)
anthrax antigen
Anti-idiopatic, anti-N-glycolyl GM3 ganglioside (N-glycolylneuraminic acid (NeuGc, NGNA) GM3 gangliosides, NeuGcGM3) Mus musculus IgM-kappa P3
Anti-idiotype
bispecific
BMP10 (bone morphogenetic protein 10)
BSG (basigin, Ok blood group, CD147)
C5 (complement 5)
CA 72-4 (tumour associated glycoprotein 72, TAG-72, TAG, HMW mucin-like glycoprotein)
CA9 (carbonic anhydrase IX, CAIX, MN, G250)
carcinoma associated antigen CTAA16.88 (complex of cytokeratin polypeptides (35-40kDa))
CCL11 (chemokine (C-C motif) ligand 11, chemokine CC 11, eotaxin1)
CCL2 (chemokine (C-C motif) 2, chemokine CC 2, monocyte chemoattractant protein-1, MCP-1, monocyte chemotactic and activating factor, MCAF, small inducible cytokine A2, SCYA2, HC11)
CCR4 (chemokine (C-C motif) receptor 4, chemokine CC receptor 4, CCR-4, CKR4, k5-5, CD194)
CD14
CD15 (3-fucosyl-N-acetyl-lactosamine, Lewis x, stage-specific embryonic antigen 1, SSEA-1)
CD19 (B lymphocyte surface antigen B4, Leu-12)
CD2 (lymphocyte function-antigen 2, LFA-2)
CD200 (OX-2)
CD22 (sialic acid binding Ig-like lectin 2, SIGLEC2, SIGLEC-2, B-lymphocyte cell adhesion molecule, BL-CAM, Leu-14)
CD33 (sialic acid binding Ig-like lectin 3, SIGLEC3, SIGLEC-3, gp67, p67)
CD38 (ADP-ribosyl cyclase 1, cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, T10)
CD3E (CD3 epsilon)
CD4 (p55)
CD40 (tumor necrosis factor receptor superfamily member 5, TNFRSF5, p50)
CD40LG (CD40 ligand, CD40L, tumor necrosis factor ligand superfamily member 5, TNFSF5, tumor necrosis factor related activation protein, TRAP, CD154)
CD44 (homing function and Indian blood group system, chondroitin sulfate proteoglycan 8, CSPG8)
CD5 (T1, LEU-1)
CD52
CD6 (Tp120)
CD70 (tumor necrosis factor superfamily member 7, TNFSF7, CD27LG, CD27L)
CD74 (major histocompatibility class II invariant chain, MH2)
CD80 (B7-1, CD28LG1)
CD86 (B7-2, CD28LG2)
CEA (anticarcinoembryonic antigen)
CEACAM3 (carcinoembryonic antigen-related cell adhesion molecule 3 , CGM1, CD66d)
CEACAM5 (carcinoembryonic antigen-related cell adhesion molecule 5, CEA, CD66e)
CEACAM8 (carcinoembryonic antigen-related cell adhesion molecule 8 , NCA-95, nonspecific cross-reacting antigen 95 kDa, granulocyte cell antigen, CGM6, CD66b)
ClfA (Clumping factor A)
complement C3b, C4b
CSF2 (colony stimulating factor 2 (granulocyte-macrophage), granulocyte-macrophage colony stimulating factor, GM-CSF)
CSF2RA (colony-stimulating factor 2(granulocyte-macrophage) receptor alpha subunit, GM-CSF-R-alpha, CD116)
CSPG4 (chondroitin sulfate proteoglycan 4, high molecular weight-melanoma-associated antigen, HMW-MAA)
CTLA4 (cytotoxic T lymphocyte-associated antigen 4, CD152)
digoxin
ED-B (fibronectin extra domain B)
EGFR (epidermal growth factor receptor, receptor tyrosine-protein kinase erbB-1, ERBB1, HER1, HER-1, ERBB)
endotoxin (lipid A, domain of lipopolyaccharide, LPS)
EPCAM (epithelial cell adhesion molecule, tumor-associated calcium signal transducer 1, TACSTD1, gastrointestinal tumor-associated protein 2, GA733-2, epithelial glycoprotein 2, EGP-2, epithelial cell adhesion molecule, Ep-CAM, KSA, KS1/4 antigen, M4S, tumor antigen 17-1A, EpCAM, CD326)
ERBB2 (epidermal growth factor receptor 2, receptor tyrosine-protein kinase erbB-2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340
ERBB3 (receptor tyrosine-protein kinase erbB-3, HER3)
Factor VII
FAP ( fibroblast activation protein, alpha)
FCER2 (immunoglobulin E Fc receptor low affinity II, Fc epsilon RII, CD23)
FCGR1 (immunoglobulin G Fc receptor high affinity I, Fc gamma RI, CD64, encoded by human FCGR1A, FCGR1B, FCGR1C)
fibrin II beta chain (NH2 terminus)
FLT1 (fms-related tyrosine kinase 1, vascular endothelial growth factor receptor 1, VEGFR-1, VEGFR, FLT, FRT, vascular permeability factor receptor)
FOLH1 (folate hydrolase, prostate specific membrane antigen, PSMA)
FOLR1 (folate receptor 1, folate receptor FR alpha, FR-alpha, adult folate-binding protein, FBP, ovarian tumor-associated antigen MOv18)
GD2 ganglioside
GD3 ganglioside
GDF2 (growth differentiation factor 2, BMP9, BMP-9)
GLP1R (glucagon-like peptide 1 receptor)
GPNMB (glycoprotein transmembrane NMB, hematopoeitic growth factor inducible neurokinin-1 type, HGFIN)
hapten NP-cap (4-hydroxy-3-nitrophenacetyl caproic acid)
HAVCR1 (hepatitis A virus cellular receptor 1, T-cell immunoglobulin and mucin domain-containing protein 1, TIM1, KIM-1)
HBV (hepatitis B virus)
HCMV (human cytomegalovirus) gB glycoprotein
HCV (hepatitis C virus)
heat shock protein 90 homolog
HGF (hepatocyte growth factor, scatter factor, SF, hepatopoeitin A)
HIV-1 (human immunodeficiency virus)
HLA-DR10 (DRB1*1001)
HLA-DRB (HLA-DR beta)
HSV (herpes simplex virus)
ICAM1 (intercellular adhesion molecule 1, ICAM-1, CD54)
ICAM3 (intercellular adhesion molecule 3, ICAM-3, CD50)
IFNA1 (interferon alpha 1, IFN alpha, IFN alpha 1/13, IFN 13)
IFNB1 (interferon beta 1, IFNB)
IFNG (interferon gamma, IFN gamma)
IgE Fc
IGF1R (insulin-like growth factor 1 receptor, IGF1-R, IGF-1R, CD221)
IGHE connecting region (CO) M1 prime (in alternatively spliced heavy chain of membrane IgE on B cells)
IL12A (interleukin 12 alpha, IL-12A, IL12 p35, CMLF1, NKSF1)
IL12B (interleukin 12 beta, IL-12B, IL12 p40, CMLF2, NKSF2)
IL13 (interleukin 13, IL-13)
IL15 (interleukin 15, IL-15)
IL17A (interleukin 17A, IL-17A)
IL17RA (interleukin 17 receptor A, CD217)
IL1A (interleukin 1 alpha, IL-1A)
IL1B (interleukin 1 beta, IL-1B)
IL22 (interleukin 22, IL-22)
IL2RA (interleukin-2 receptor, alpha subunit, IL-2RA, TAC, CD25)
IL2RB (interleukin-2 receptor beta subunit, IL-2RB, p70, CD122)
IL4 (interleukin 4, IL-4)
IL5 (interleukin 5, IL-5)
IL5RA (interleukin 5 receptor alpha subunit, CD125)
IL6 (interleukin 6, IL-6)
IL6R (interleukin 6 receptor, IL-6R, CD126)
IL8 (interleukin 8, IL-8)
IL9 (interleukin 9, IL-9, T cell growth factor p40)
ITGA2 (integrin alpha 2, GPIa, subunit of the alpha2beta1 integrin (VLA-2, collagen receptor), CD49b)
ITGA2B_ITGB3 (integrin alpha2b_beta3, integrin αIIbβ3, GPIIbIIIa, fibrinogen receptor, CD41_CD61)
ITGA4 (integrin apha 4 subunit, CD49d)
ITGA4_ITGB7 (integrin alpha4_beta7, integrin α4β7, lymphocyte Peyer's patch adhesion molecule 1, LPAM-1)
ITGA5 (integrin alpha 5 subunit, CD49e)
ITGAE_ITGB7 (integrin alphaE_beta7, integrin αEβ7, human mucosal lymphocyte antigen 1, HML-1)
ITGAL (integrin alpha L subunit, lymphocyte function associated antigen 1, CD11a)
ITGAV_ITGB3 (integrin alphaV_beta3, integrin αVβ3, CD51_GPIIIa, vitronectin receptor, VNR, CD51_CD61)
ITGB1 (integrin beta1 subunit, GPIIa, CD29)
ITGB2 (integrin beta2 subunit, LFA-1, MAC-1, CD18)
KDR (kinase insert domain receptor, vascular endothelial growth factor receptor 2, VEGFR2, VEGF-R2, FLK1, CD309)
LTA (lymphotoxin alpha, TNF superfamily member 1, TNFSF1, LT)
LTB (lymphotoxin beta, TNF superfamily member 3, TNFSF3, p33)
lysozyme
MET (met proto-oncogene, hepatocyte growth factor HGF receptor, HGFR, scatter factor SF receptor, HGF/SF receptor, tyrosine protein kinase c-met, papillary renal cell carcinoma 2, RCCP2)
MS4A1 (membrane-spanning 4-domains subfamily A member 1, CD20)
MSLN (mesothelin, pre-pro-megakaryocyte-potentiating factor, megakaryocyte potentiating factor, MPF, CAK1)
MST1R (macrophage stimulating 1 receptor, macrophage stimulating protein receptor, MSP receptor, c-met-related tyrosine kinase, protein- tyrosine kinase 8, PTK8, RON, p185-Ron, CD136)
MSTN (myostatin, growth differentiation factor 8, GDF8)
MUC1 (mucin 1, polymorphic epithelial mucin, PEM, episialin, CD227)
MUC1 sialylated carbohydrate, tumour-associated (CA242, cancer antigen 242)
MUC16 (mucin 16, MUC-16, cancer antigen 125, CA125)
MUC5AC (mucin 5AC, mucin 5 subtypes A and C tracheobronchial/gastric)
myosin, cardiac
N-glycolyl GM3 ganglioside (N-glycolylneuraminic acid (NeuGc, NGNA) GM3 ganglioside, NeuGcGM3)
NCA-90 (nonspecific cross-reacting antigens 90kDa glycoproteins, granulocyte cell antigen)
NCAM1 (neural cell adhesion molecule 1, NCAM-1, NCAM, CD56)
Nectin-4
NGF (nerve growth factor, nerve growth factor beta polypeptide, NGFB, beta-NGF)
NIP-cap (3-iodo-4-hydroxy-5-nitrophenyl-acetyl caproic acid)
NRP1 (neuropilin 1, NRP, vascular endothelial cell growth factor 165 receptor, VEGF165 receptor, VEGF165R, CD304)
PDGFRA (platelet-derived growth factor receptor alpha subunit, PDGFR2, CD140a)
phosphatidylserine
PSCA (prostate stem cell antigen)
Pseudomonas aeruginosa PcrV (located at the tip of the syringe-like TTSS (Type Three Secretion System))
Pseudomonas aeruginosa serotype IATS O11
rabies virus glycoprotein
RHD (Rhesus blood group D antigen, RhD, CD240D)
RSV (human respiratory syncytial virus, glycoprotein F)
RTN4 (reticulon 4, neurite outgrowth inhibitor, NOGO)
SDC1 (syndecan-1, CD138)
SELE (E-selectin, CD62E)
SELL (L-selectin, CD62)
SELP (P-selectin, CD62)
SFRP1 (selected frizzled-related protein 1, fusion regulatory protein 1, FRP-1)
Shiga-like toxin II B subunit
SLAMF7 (SLAM family member 7, CD2 subset 1, CS1, CD2-like receptor-activating cytotoxic cells, CRACC,19A24, CD319)
SLC3A2 (solute carrier family 3 (activators of dibasic and neutral amino acid transport) member 2, 4F2 antigen heavy chain, 4F2HC, CD98 heavy chain, CD98hc, CD98)
SOST (sclerostin)
Staphylococcus epidermidis lipoteichoic acid
T cell receptor (TR) TR alpha_beta
TGFB1 (transforming growth factor beta1, TGF beta)
TGFB2 (transforming growth factor beta 2)
TNC (tenascin C, hexabrachion, HXB)
TNF (tumor necrosis factor (TNF) superfamily member 2, TNFSF2, TNF-alpha, TNFA)
TNFRSF10A (tumor necrosis factor receptor (TNFR) superfamily member 10A, death receptor 4, DR4, TNF-related apoptosis-inducing ligand receptor 1, TRAILR1, TRAIL-R1, TR-1, CD261)
TNFRSF10B (tumor necrosis factor receptor (TNFR) superfamily member 10B, death receptor 5, DR5, TNF-related apoptosis-inducing ligand receptor 2, TRAILR2, TRAIL-R2, TR-2, CD262)
TNFRSF12A (tumor necrosis factor receptor (TNFR) superfamily member 12A, fibroblast growth factor (FGF)-inducible 14 kDa protein, Fn14, TNF-like weak inducer of apoptosis (Tweak) receptor, Tweak receptor, TweakR, CD266)
TNFRSF8 (tumor necrosis factor receptor (TNFR) superfamily member 8, CD30)
TNFRSF9 (tumor necrosis factor receptor (TNFR) superfamily member 9, 4-1BB, T cell antigen ILA, CD137)
TNFSF11 (tumor necrosis factor (TNF) superfamily member 11, osteoclast differentiation factor, ODF, OPGL, RANKL, TRANCE, CD254)
TNFSF13 (tumor necrosis factor (TNF) superfamily member 13, a proliferation-including ligand, APRIL, CD256)
TNFSF13B (tumor necrosis factor (TNF) superfamily member 13B, B cell activating factor, BAFF, TALL1, BLyS, B lymphocyte activator, CD257)
TNFSF14 (tumor necrosis factor (TNF) superfamily member 14, LIGHT, HVEM-L, CD258)
TNFSF4 (tumor necrosis factor (TNF) superfamily member 4, OX40 ligand, OX-40L, TAX transcriptionally-activated glycoprotein 1, TXGP1, gp34, CD252)
toxin
TPBG (trophoblast glycoprotein, 5T4)
TYRP1 (tyrosinase- related protein 1, 5,6-dihydroxyindole-2-carboxylic acid oxidase, DHICA oxidase, TRP1, melanoma antigen gp75)
VAP-1 (vascular adhesion protein)
VEGFA (vascular endothelial growth factor A, VEGF-A, VEGF)
VIM (vimentin)
VWF (von Willebrand factor) A1 domain

WELCOME!to IMGT/mAb-DB

THE INTERNATIONAL IMMUNOGENETICS INFORMATION SYSTEM®

IMGT/mAb-DB Query page

Search by:

Displayed fields:

WELCOME!
to IMGT/mAb-DB

THE
INTERNATIONAL
IMMUNOGENETICS
INFORMATION SYSTEM®