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| Here you are: IMGT Web resources > IMGT Scientific chart > 2. Numbering |
Correspondence between V numberings
Correspondence between the IMGT unique Lefranc numbering and the different Kabat numberings (vertical display of examples)
Correspondence between the IMGT unique Lefranc numbering and the different numberings (horizontal display)
Correspondence between numberings for CDR of different lengths (horizontal display)
| Click here for: | CDR1-IMGT
CDR3-IMGT |
CDR-IMGT lengths of the IG proteins quoted as examples
CDR2-IMGT
There are no gaps and therefore no correspondence between the numberings shown in this table.
Click here for correspondence between the IMGT unique Lefranc numbering [1], Kabat [2] and Chothia [3-5] numberings for CDR2 of different lengths.
Brackets indicate the limits of the CDR in each numbering.
Click on the protein name for the CDR2-IMGT 3D structure.
For more information on the proteins, see Protein with known 3D structures-Identification and Colliers de Perles: Human Immunoglobulins
IMGT FR2-IMGT CDR2-IMGT FR3-IMGT unique CDR CDR2- numbering [1] 55 [56 57 58 59 60 61 62 63 64 65] 66 67 68 69 70 71 72 73 74 length [2] IMGT [1]
IGHV [2] [50 51 52 52A 52B 52C 53 54 55 56 57 58 59 60 61 62 63 64 - 65] 19 10
[50 51 52 52A 52B 53 54 55 56 57 58 59 60 61 62 63 64 - 65] 18 9
[50 51 52 52A 53 54 55 56 57 58 59 60 61 62 63 64 - 65] 17 8
[50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 - 65] 16 7
H2 "canonical H2 CDR2- Example
structure" length [5] IMGT [1] of proteins
IGHV [3] [4] [5] 50 51 52 [52a 52b 52c 53 54 55] 56 57 58 59 60 61 62 63 64 - 65 4 6 10 McPC603,4-4-20
50 51 52 [52a 52b 53 54 55] 56 57 58 59 60 61 62 63 64 - 65 - 5 9
50 51 52 [52a 53 54 55] 56 57 58 59 60 61 62 63 64 - 65 2,3 4 8 Kol, J539
50 51 52 [53 54 55] 56 57 58 59 60 61 62 63 64 - 65 1 3 7 Newm
IMGT FR2-IMGT CDR2-IMGT FR3-IMGT unique CDR CDR2- numbering [1] 55 [56 57 58 59 60 61 62 63 64 65] 66 67 68 69 70 71 72 73 74 length [2] IMGT [1]
IGKV [2] 49 [50 51 52 53 54 55 56] 57 58 59 - 60 7 3
L2 "canonical L2 CDR2- Example
structure" length [5] IMGT [1] of proteins
IGKV [3] [4] [5] 49 [50 51 52] 53 54 55 56 57 58 59 - 60 1 3 3 Rei, McPC603,
J539
IMGT FR2-IMGT CDR2-IMGT FR3-IMGT CDR CDR2- unique length [2] IMGT [1] numbering [1] 55 [56 57 58 59 60 61 62 63 64 65] 66 67 68 69 70 71 72 73 74 7 3
IGLV [2] 49 [50 51 52 53 54 55 56] 57 58 59 - 60
L2 "canonical L2 CDR2- Example
structure" length [5] IMGT [1] of proteins
IGLV [3] [4] [5] 49 [50 51 52] 53 54 55 56 57 58 59 - 60 1 3 3 Kol, Rhe
References:
| [1] | Lefranc, M.-P., The Immunologist, 7, 132-136 (1999). |
| [2] | Kabat, E.A. et al., In: Sequences of Proteins of Immunological Interest, NIH Publication, 91-3242 (1991). |
| [3] | Chothia, C. and Lesk, A.M., J. Mol. Biol., 196, 901-917 (1987). |
| [4] | Chothia, C. et al., Nature, 342, 877-883 (1989). |
| [5] | Al-Lazikani, B. et al., J. Mol. Biol., 273, 927-948 (1997). |
Created: 16/05/2001
Last updated: Wednesday, 29-Jun-2011 17:04:15 CEST
Author: Lisa Truong
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
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Marie-Paule.Lefranc@igh.cnrs.fr
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