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Abbreviations

A / B / C / D / E / F / G / H / I / J / K / L / M / N / O / P / Q / R / S / T / U / V / W / X / Y / Z

a or A adenine (purine base of DNA and RNA)
AA amino acid
Å angstrom (angström in french) (10-10 meter, 1 Å = 0.1 nm)
Ab antibody
ACPA anti-citrullinated protein/peptide antibody
AID activation-induced cytidine deaminase
BcR B cell receptor (on the surface of mature B cells, comprising mIG associated to the coreceptors CD79A (Ig-alpha, mb-1) and CD79B (Ig-beta, B29))
BM bone marrow
bp base pair
BrMRBc bromelain-treated mouse red blood cells
c or C cytosine (pyrimidine base of DNA and RNA)
C constant
CCP cyclic citrullinated (deiminated) peptide
CCP1, CCP2, CCP3: first, second, third generation anti-CCP assay
cDNA complementary DNA
CDR complementarity determining region
CDR-IMGT complementarity determining region according to IMGT unique numbering
CH immunoglobulin heavy constant exon or domain
CLL chronic lymphocytic leukemia
CNRS Centre National de la Recherche Scientifique
CNS central nervous system
CO CONNECTING-REGION (IMGT label)
CPT citrate/pyridoxal 5'-phosphate/Tris
CSR class switch recombination
CY CYTOPLASMIC-REGION (IMGT label)
D diversity
Da dalton (1 Da=1.66x10-24 g)
dC deoxycytidine
DCI Dénomination Commune Internationale (INN in English)
DDBJ DNA DataBank of Japan (nucleotide sequence database)
DSB double-strand break
dsDNA double-stranded DNA
dU deoxyuridine
E enhancer
EBV Epstein-Barr virus
EDTA ethylenediamine tetraacetic acid
EMBLBank European Molecular Biology Laboratory nucleotide sequence database
ER endoplasmic reticulum
FAM fluorescein-5-carboxamide (or 5-carboxyfluorescein)
FAQ frequently asked question
FL follicular lymphoma
FnSF fibronectin superfamily
FR framework region
FR-IMGT framework region according to IMGT unique numbering
Fv Fragment variable
g or G guanine (purine base of DNA and RNA)
Gb gigabase (109 bases; a billion bases)
GC germinal center
gDNA genomic DNA
GenBank US nucleotide sequence database
HCV hepatitis C virus
HGNC Human Genome Organisation (HUGO) Nomenclature Committee
HLA human leucocyte antigen (human MHC)
HUGO HUman Genome Organisation
IG immunoglobulin (for locus, gene, chain or receptor)
Ig immunoglobulin (as part of a IG class name, e.g. IgM, or of a prefix Ig-like, IgSF), see also IG
IGH IG heavy
IGHV IG heavy variable
IGK IG kappa
IGKV IG kappa variable
IGL IG lambda
IGLV IG lambda variable
IgSF immunoglobulin superfamily
IMGT IMGT®, the international ImMunoGeneTics information system®
INN International Nonproprietary Name (DCI in French)
J joining
kb kilobase
kDa kilodalton
LIGM-DB Laboratoire d'ImmunoGénétique Moléculaire DataBase (Immunoglobulin and T cell receptor sequence database), part of IMGT
mAb monoclonal antibody
Mb megabase (106 bases)
MHC major histocompatibility complex
MhcSF major histocompatibility complex superfamily
mIG membrane IG (defined has having a transmembrane region TM, refers usually to IG on the B cell surface and part of the BcR). If needed, localization can be added: surface mIG for mIG on cell surface or ER mIG for mIG on endoplasmic reticulum membrane.
mIgM membrane IgM (also for the other classes e.g. mIgD and subclasses e.g. mIgG3)
MMP matrix metalloproteinase
Nb or nb number
nm nanometer (10-9 meter, 1 nm = 10 Å) (better to use nm rather than Å)
nt nucleotide
OMIM Online Mendelian Inheritance in Man (MIM)
OMS Organisation mondiale de la Santé (WHO in English)
ORF open reading frame
PB peripheral blood
pMHC peptide-MHC complex
PtC phosphatidyl choline
RA rheumatoic arthritis
RBC red blood cell
RF rheumatoid factor
RPI related proteins of the immune system
RS recombination signal
S switch
SE shared epitope (refers for HLA-DRB1 to the RAA pattern at positions 68-70, according to the IMGT unique numbering for G-DOMAIN, but the use of SE for this pattern is inappropriate and not recommended)
SHM somatic hypermutation
sIgM secreted IgM
SLE systemic lupus erythematosus
SRS Sequence Retrieval System, a database query system developed by EMBL
ssDNA single-stranded DNA
SSP-PCR sequence specific primer polymerase chain reaction
t or T thymine (pyrimidine base of DNA)
TAMRA 5-(or/and -6)-carboxytetramethylrhodamine
TcR T cell receptor (on the surface of T cells, comprising one TR associated with the coreceptor CD3 proteins, CD3G, CD3D, CD3E, CD3Z, assembled in dimers)
TdT terminal deoxynucleotidyl transferase
TM TRANSMEMBRANE-REGION (IMGT label)
TR T cell receptor (for locus, gene, chain or receptor)
TRA TR alpha
TRAV TR alpha variable
TRB TR beta
TRBV TR beta variable
TRG TR gamma
TRGV TR gamma variable
TRD TR delta
TRDV TR delta variable
UDG uracil-DNA glycosylase
V variable
WHO World Health Organization (OMS in French)
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