IMGT Lexique
Glycosylation
Glycosylation of IgG-Fc antibodies determines biologic functions mediated through cellular Fc receptors (FcγR), the C1q component of the classical pathway of complement, mannan binding ligand (MBL) and the mannose receptor (MR). FcγR and C1 binding are dependent on core oligosaccharide structure, MBL and MR by terminal sugar residues (glycoforms).
Authors: Amina Mrani Dassouli and Marie-Paule Lefranc
Editor: Chantal Ginestoux
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only,
provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics
information system® http://www.imgt.org
(founder and director: Marie-Paule Lefranc, Montpellier, France)."
References to cite:
Lefranc, M.-P. et al.,
Nucleic Acids Research, 27, 209-212 (1999)
Cover of NAR;
Ruiz, M. et al.,
Nucleic Acids Research, 28, 219-221 (2000);
Lefranc, M.-P.,
Nucleic Acids Research, 29, 207-209 (2001);
Lefranc, M.-P.,
Nucleic Acids Res., 31, 307-310 (2003);
Lefranc, M.-P. et al.,
In Silico Biol., 5, 0006 (2004) [Epub],
5, 45-60 (2005);
Lefranc, M.-P. et al.,
Nucleic Acids Res., 33, D593-D597 (2005)
Full text;
Lefranc, M.-P. et al.,
Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838
Full text.
For any other use please contact Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr.
IMGT founder and director: Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
Bioinformatics manager: Véronique Giudicelli
Veronique.Giudicelli@igh.cnrs.fr
Computer manager: Patrice Duroux
Patrice.Duroux@igh.cnrs.fr
Webmaster: Chantal Ginestoux
Chantal.Ginestoux@igh.cnrs.fr
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