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IMGT Genes on the Ensembl Genome Browser

"IMGT Genes" have been available on the Ensembl Genome Browser since October 28, 2005. The links below give access to the human IG and TR loci in

To see "IMGT Genes":

• Click on one of the links below. Select 'Configure this page' (left panel).
• In the new window, click on 'Genes' (main panel).
• In 'External data sources', select 'IMGT DAS Sources' and in the pop up menu 'Normal', for example. Click on the 'save and close' in the upper right corner.
  'IMGT DAS Sources' appears in the second box at the bottom of the page.

Once "IMGT Genes" are displayed, clicking on an individual IMGT Gene opens a small window with a direct link to IMGT/GENE-DB.

Genes in the forward (FWD) orientation on the chromosome are displayed above the DNA (contigs), whereas genes in the reverse (REV) orientation are located below.

1. Homo sapiens IGH locus at 14q32.33:
   • IGHV on Ensembl Genome Browser
   • IGHD and IGHJ on Ensembl Genome Browser
   • IGHC on Ensembl Genome Browser
2. Homo sapiens IGK locus at 2p11.2:
   • IGKV (proximal cluster), IGKJ and IGKC on Ensembl Genome Browser
   • IGKV (duplicated distal cluster) on Ensembl Genome Browser
3. Homo sapiens IGL locus at 22q11.2:
   • IGL on Ensembl Genome Browser
4. Homo sapiens TRA/TRD locus at 14q11.2:
   • TRA/TRD on Ensembl Genome Browser
5. Homo sapiens TRB locus at 7q34: (1)
   • TRB on Ensembl Genome Browser
6. Homo sapiens TRG locus at 7p14:
   • TRG on Ensembl Genome Browser

"IMGT Genes" on the Ensembl Genome Browser were set up by Emmanuel-Jean Servier since 2006 (DESS de Bioinformatique, Université Montpellier 2 September 2005, and LIGM, October 2005) and has been maintained by Jérôme Lane and Patrice Duroux since 2011.

Notes:

(1)	Be aware that in the GRCh37.p2 assembly, the TRB locus has major errors (gaps, inversion). The correct sequence is available in IMGT/LIGM-DB in L36092.

See also:

• Genomic orientation
• IMGT Repertoire
• IMGT/CloneSearch
• IMGT/GeneSearch
• IMGT/GeneView
• IMGT/LocusView
• Tools

Created: 21/02/2006
Last updated: Friday, 26-Aug-2011 22:30:10 CEST
Authors: Jérôme Lane, Patrice Duroux, Emmanuel-Jean Servier and Marie-Paule Lefranc
Editor: Chantal Ginestoux
Contact: Marie-Paule Lefranc

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Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

     

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