@ "arrobas" (typographic character) used in the HGNC (HUGO Nomenclature Committee) database for 'gene cluster in chromosomal region'.
20 IG and TR entries have the arrobas "@" in the HGNC symbol. These entries were created in HGNC, Entrez Gene and/or OMIM to avoid a loss of information and to collect data entered in these databases, prior to the entry of the individual genes. The HGNC symbols are used for links between IMGT® and the genome databases but they are not exhaustive. Indeed, they correspond to:
| HGNC symbol |
IMGT name |
|
|---|---|---|
| the 3 IMGT IG loci | IGH@ | IGH locus |
| IGK@ | IGK locus | |
| IGL@ | IGL locus | |
| the 4 IMGT TR loci | TRA@ | TRA locus |
| TRB@ | TRB locus | |
| TRG@ | TRG locus | |
| TRD@ | TRD locus | |
| 4 (of 12) IMGT IG chromosomal orphon sets | IGHVOR15@ | IGHV/OR15 |
| IGHVOR16@ | IGHV/OR16 | |
| IGHDOR15@ | IGHD/OR15 | |
| IGKVOR2@ | IGKV/OR2 | |
| the IMGT TR chromosomal orphon set | TRBVOR9@ | TRBV/OR9 |
| 8 (of 10) IMGT IG groups | IGHV@ | IGHV group |
| IGHD@ | IGHD group | |
| IGHJ@ | IGHJ group | |
| IGKV@ | IGKV group | |
| IGKJ@ | IGKJ group | |
| IGLV@ | IGLV group | |
| IGLJ@ | IGLJ group | |
| IGLC@ | IGLC group | |
| none of the 14 IMGT TR groups |
The IMGT 'group' concept comprises genes of the major loci and of the chromosomal orphon sets, whereas the HGNC IG group symbols only refer to genes of the major loci.