IMGT Repertoire (IG and TR)

Colliers de Perles

V-REGION

 

• Figure to be filled in for new sequences
• For figure with positions of conserved hydrophobic amino acids

V-DOMAIN (V-J-REGION and V-D-J-REGION)

 

For more V-DOMAINs, query "V-DOMAIN" in IMGT/3Dstructure-DB and click on "Collier de Perles" in the IMGT/3Dstructure-DB cards.
* Click on CDR-IMGT lengths in the table.

C-DOMAIN

 

Colliers de Perles with hydrogen bonds

• IGHV-D-J: Mouse 231

For more V-DOMAINs with hydrogen bonds, query "V-DOMAIN" in IMGT/3Dstructure-DB and click on "Collier de Perles" in the IMGT/3Dstructure-DB cards.

3D representations

V-DOMAIN

 

C-DOMAIN

 

FR-IMGT and CDR-IMGT lengths (V-REGION and V-DOMAIN)

FR-IMGT lengths for comparison of humanized antibodies

FR-IMGT and CDR-IMGT (V-REGION)

 

CDR1-IMGT (summary) and correspondence with "canonical structures"

 

CDR2-IMGT (summary) and correspondence with "canonical structures"

 

CDR3-IMGT (V-DOMAIN)

For IG and TR with known 3D structures, query IMGT/3Dstructure-DB.

CDR-IMGT 3D structures

CDR1-IMGT

• IGLV: Human

CDR2-IMGT

• IGLV: Human

Strand and loop lengths (C-DOMAIN)

 

Examples of C-DOMAINs

Protein displays

• IG-Light C-DOMAINs: Human, Mouse, Teleostei
• TR C-DOMAINs: Human, Mouse

Strand and loop lengths

• IG-Light C-DOMAINs: Human, Mouse, Teleostei

Proteins with known 3D structures

Overview

• Immunoglobulin: Human

Identification and Colliers de Perles

• IGH: Human
• IGK: Human
• IGL: Human

Protein display V-DOMAIN

• IGHV-D-J: Human
• IGKV-J: Human
• IGLV-J: Human

Classification by gene names

• IGHV: Human
• IGKV: Human
• IGLV: Human

Classification by CDR-IMGT lengths

• IGHV-D-J: Human
• IGKV-J: Human
• IGLV-J: Human

IG proteins updates from 09/05/2001 and TR proteins, are available in IMGT/3Dstructure-DB.