IMGT/3Dstructure-DB card: 1ao7

Side view (backbone model)
Complex TcR ab A6/Tax/HLA-A*0201 (backbone model)
View from above the CDRs (backbone model)
Collier de Perles: Human TRA V-J REGION

Human rearranged TRBV6-5 - TRBD2 - TRBJ2-7

[5.6.14]

Legend:

• Amino acids are shown in the one-letter abbreviation.
• Hydrophobic amino acids (hydropathy index with positive value) and Tryptophan (W) found at a given position in more than 50 % of analysed Ig and TcR sequences are shown in blue.
• All Proline (P) are shown in yellow.
• The CDR-IMGT are limited by amino acids shown in squares, which belong to the neighbouring FR-IMGT. The CDR3-IMGT is described using the IMGT unique numbering for V-DOMAIN.
• Hatched circles or squares correspond to missing positions according to the IMGT unique numbering for V-REGIONs. Missing positions of the CDRs are not shown in this representation.
• Arrows indicate the direction of the beta strands and their different designations in 3D structure.
• For the TcR, the proteolytic cleavage site between the leader peptide and the V-REGION is putative and the assignment of amino acid 1 to one or the other region is uncertain.

Created: 19/12/1997
Last updated: Wednesday, 29-Jun-2011 17:05:52 CEST
Authors: Manuel Ruiz and Elodie Foulquier
Contact: Marie-Paule Lefranc

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