In the absence of germline sequences, gene assignments are provisional.
In the absence of germline sequences, gene assignments are provisional.
| TRGV
genes |
FR1-IMGT 1 to 26 |
CDR1-IMGT 27 to 38 |
FR2-IMGT 39 to 55 |
CDR2-IMGT 56 to 65 |
FR3-IMGT 66 to 104 |
CDR3-IMGT (germline V-GENE) 105 to 115 |
| (22,26) | (3,5,8) | (17) | (6 to 8) | (38 to 39) | (4,5,6,7,10 ) | TRGV1S1 to TRGV1S3 |
5 | 8 | -1 (aa 82) | 4 (1) |
| TRGV2S1 | 3 | 8 | -1 (aa 82) | 7 (1) | ||
| TRGV3S1 to TRGV3S2 |
8 | 7 | 4 (1) | |||
| TRGV4S1 | 8 | 6 | 4 (1) | |||
| TRGV5S1 to TRGV5S10 TRGV5S11 to TRGV5S13 TRGV5S14 to TRGV5S16 TRGV5S17 to TRGV5S19 TRGV5S20 |
-4 (aa 5 to 8) -4 (aa 5 to 8) -4 (aa 5 to 8) -4 (aa 5 to 8) -4 (aa 5 to 8) |
5 5 5 5 5 |
8 8 8 8 8 |
-1 (aa 82) -1 (aa 82) -1 (aa 82) -1 (aa 82) -1 (aa 82) |
4 (1) 5 (1) 6 (1) 7 (1) 10 (1) (2) |
IMGT notes:
| (1) | Probable CDR3-IMGT length, but needs to be confirmed with germline sequences. |
| (2) | The JUNCTION of the rearranged TRGV5S20 (D16124) is 19 AA long which would suggest a germline CDR3-IMGT of 10 AA. However, in the absence of germline V and J genes, it is not possible to delimit the V-REGION and J-REGION, respectively. |
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
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IMGT founder and director: Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
Bioinformatics manager: Véronique Giudicelli Veronique.Giudicelli@igh.cnrs.fr Computer manager: Patrice Duroux Patrice.Duroux@igh.cnrs.fr Webmaster: Chantal Ginestoux Chantal.Ginestoux@igh.cnrs.fr |
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Citing IMGT © Copyright 1995-2012 IMGT®, the international ImMunoGeneTics information system® |
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