IMGT Repertoire (IG and TR)
Alignment of alleles: Rabbit (Oryctolagus cuniculus) IGHA9
When several alleles are shown, the nucleotide mutations and amino acid
changes for a given codon are indicated in red letters. These polymorphic mutations are reported in
Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the
IMGT unique numbering.
Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
Exon names are shown between parentheses on the first line.
Cysteine involved in the disulfide bridge are shown in purple.
STOP-CODON is indicated by an asterisk.
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CH-S and in pages edited before 14/10/2009).
1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11 12
D P A T T P S L F P L S L P C P
X82115 IGHA9*01 F (CH1) ... ... ... ... gat ccc gcg acc acc ccc agc ctc ttc ccg ctg agc ctg ccc tgt cct
_____AB_____ ____________
15.1 15.3
13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28 29
E C A H P V V V G C L I R G F F
X82115 IGHA9*01 F (CH1) gag tgt ... ... ... ... gca cat cct gtg gtc gtc ggc tgc ctg atc cgg ggc ttc ttc
_______BC___________________ _____________CD_________
45.1 45.3 45.5
30 31 34 35 36 37 38 39 40 41 42 43 44 45 45.2 45.4 45.6
P L G P L N V S W N G S E
X82115 IGHA9*01 F (CH1) ccc ctg ... ggc cct ctg aat gtg agc tgg aac ggc agc gag ... ... ... ... ... ...
____ ___________________________DE_______________
45.7 84.1 84.3 84.5 84.7 85.6 85.4
77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
G G V I F P P V P S P S S S
X82115 IGHA9*01 F (CH1) ... ggg ggc gtg atc ttc cct cct gtc ccg tct ccc tcc tca ... ... ... ... ... agc
____________ ___EF___
85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98 99
L Y T T S S L L S L T D D Q C P R D
X82115 IGHA9*01 F (CH1) ctc tac acc aca agc agc ctg ctg agc ctg aca gat gac cag tgt ... ... cct aga gat
_________________________FG_________________________
100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119
G N V T C H V E H N Y D E G Q D L
X82115 IGHA9*01 F (CH1) gga aat gtg acc tgc cat gtg gag cac aac ... ... ... tat gat gag ggc cag gat ctg
120 121 122 123 124
T V P C Q
X82115 IGHA9*01 F (CH1) act gtg ccc tgc caa
1 2 3 4 5 6 7 8 9 10
D C H C Y C P P T S
X82115 IGHA9*01 F (H) gac tgc cac tgc tac tgc ccc ccc acc tcc
1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11 12
C G E P S L S L Q R P D I G
X82115 IGHA9*01 F (CH2) ... ... ... ... ... ... tgc ggg gag ccc agc ctg tcc ctg cag cgg cca gac atc ggg
_____AB_____ ____________
15.1 15.3
13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28 29
D L L L E S K A S L T C T L S G L K
X82115 IGHA9*01 F (CH2) gac ctg ctc ctg ... ... gaa tcg aag gcc agc ctc acc tgc acc ctg agc ggc ctg aag
_______BC___________________ _____________CD_________
45.1 45.3 45.5
30 31 34 35 36 37 38 39 40 41 42 43 44 45 45.2 45.4 45.6
D P E G A V F T W E P T N G N E
X82115 IGHA9*01 F (CH2) gac ccc ... gag ggc gcc gtc ttc acc tgg gag ccc aca aac ggg aac gaa ... ... ...
____ ___________________________DE_______________
45.7 84.1 84.3 84.5 84.7 85.6 85.4
77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
P V Q Q S V Q S Y P C G
X82115 IGHA9*01 F (CH2) ... ccc gtc cag cag agc gtc cag agt tac ccg tgc ggc ... ... ... ... ... ... ...
____________ ___EF___
85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98 99
C Y S V S S V L P G C A E P W N A G
X82115 IGHA9*01 F (CH2) tgc tac agt gtg tcc agc gtg ctg ccc ggc tgt gcg gag ccc tgg ... ... aat gcg ggg
_________________________FG_________________________
100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119
T E F T C T V T H P E I E G G S L T A
X82115 IGHA9*01 F (CH2) aca gag ttc acc tgc aca gtc acc cac cct gag ... ata gag ggc ggc tcc ctg aca gcc
120 121 122 123 124 125
T I S I S R
X82115 IGHA9*01 F (CH2) acc atc agc atc agc aga
1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11 12
G S L T P P Q V H L L P P P T E
X82115 IGHA9*01 F (CH3) ... ... ... ... ggc agc ctc acc cca ccc cag gtc cac ctg ctg cca ccg ccg act gag
_____AB_____ ____________
15.1 15.3
13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28 29
E L A L N E Q V T L T C L V Q G F S
X82115 IGHA9*01 F (CH3) gag ctc gcc ctg ... ... aat gag cag gtg acg ctc acc tgc ctg gtg cag ggc ttc agc
_______BC___________________ _____________CD_________
45.1 45.3 45.5
30 31 34 35 36 37 38 39 40 41 42 43 44 45 45.2 45.4 45.6
P K D V L V S W T H N G T L V V P K
X82115 IGHA9*01 F (CH3) ccc ... ... aag gac gtg ctg gtg tcc tgg aca cac aac ggc acc ctg gtg gtc ccc aaa
____ ___________________________DE_______________
45.7 84.1 84.3 84.5 84.7 85.6 85.4
77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
D S Y L V W K P L P E P G Q D P T
X82115 IGHA9*01 F (CH3) gac agc tac ctg gtg tgg aag ccc ctg cct gag ccc ggc cag gac ... ... ... ccc acc
____________ ___EF___
85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98 99
T Y A V T S L L R V S A E D W N Q G
X82115 IGHA9*01 F (CH3) acc tac gct gtc acc agc ctg ctg cgc gtg tcg gcc gag gac tgg ... ... aac cag ggg
_________________________FG_________________________
100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119
D S Y S C V V G H E G L A E H F T Q K
X82115 IGHA9*01 F (CH3) gac agc tac tcc tgc gtg gtg ggc cat gag ggc ... ctg gcc gag cac ttc acc cag aag
______________________________________CH-S__
120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139
T I D R Q A G K P T H V N V S V V
X82115 IGHA9*01 F (CH3) acc atc gac cgc caa gcg ... ... ... ggt aaa ccc acc cac gtc aac gtg tct gtg gtc
____________________________________
140 141 142 143 144 145 146 147 148
V A D V E A V C Y
X82115 IGHA9*01 F (CH3) gtg gca gac gtg gaa gcc gtg tgc tac
Last updated: Tuesday, 03-Apr-2012 08:20:23 CEST
Authors: Claire Poiron and Christèle Martinez-Jean
Editor: Chantal Ginestoux
Contact: Marie-Paule Lefranc
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References to cite:
Lefranc, M.-P. et al.,
Nucleic Acids Research, 27, 209-212 (1999)
Cover of NAR;
Ruiz, M. et al.,
Nucleic Acids Research, 28, 219-221 (2000);
Lefranc, M.-P.,
Nucleic Acids Research, 29, 207-209 (2001);
Lefranc, M.-P.,
Nucleic Acids Res., 31, 307-310 (2003);
Lefranc, M.-P. et al.,
In Silico Biol., 5, 0006 (2004) [Epub],
5, 45-60 (2005);
Lefranc, M.-P. et al.,
Nucleic Acids Res., 33, D593-D597 (2005)
Full text;
Lefranc, M.-P. et al.,
Nucleic Acids Research 2009 37:
D1006-D1012; doi:10.1093/nar/gkn838
Full text.
For any other use please contact Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr.
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