IMGT Repertoire (IG and TR)
Alignment of alleles: Rabbit (Oryctolagus cuniculus) IGKC
When several alleles are shown, the nucleotide mutations and amino acid
changes for a given codon are indicated in red letters. These polymorphic mutations are reported in
Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the
IMGT unique numbering.
Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
Exon names are shown between parentheses on the first line.
Cysteine involved in the disulfide bridge are shown in purple.
STOP-CODON is indicated by an asterisk.
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CH-S and in pages edited before 14/10/2009).
1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11 12
X D P V A P T V L I F P P A A D
K01360 IGKC1*01 F ... ... ... ... ngt gat cca gtt gca cct act gtc ctc atc ttc cca cca gct gct gat
S
K01362 IGKC1*02 F ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- t-- --- ---
A T L S P A
K01363 IGKC1*03 F ... ... ... ... -t- -c- a-- t-g --- --- --- --- --- --- --- --- --- t-- c-- -c-
X D P I L S
X00674 IGKC1*04 F ... ... ... ngt ga- cc- --- a-- --g --- --- --- --- c-- --- --- --- t-- --- ---
X D P I L S
X03050 IGKC1*05 ORF (1) ... ... ... ngt ga- cc- --- a-- --g --- --- --- --- c-- --- --- --- t-- --- ---
A T L S P A
M37809 IGKC1*06 F ... ... ... ... -t- -c- a-g t-g --- --- --- --- --- --- --- --- --- t-- c-- -c-
S P A
M22542 IGKC1*07 F ... ... ... ... -t- --- --- --- --- --- --- --- --- --- --- --- --- t-- c-- -c-
S P A
Z48308 IGKC1*08 F ... ... ... ... -t- --- --- --- --- --- --- --- --- --- --- --- --- t-- c-- -c-
C D P I L S
K01359 IGKC1*09 (F) (cDNA) ... ... ... tgt ga- cc- --- a-- --g --- --- --- --- c-- --- --- --- t-- --- ---
_____AB_____ ____________
15.1 15.3
13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28 29
Q V A T G T V T I V C V A N K Y F
K01360 IGKC1*01 F cag gtg gca ... ... ... act gga aca gtc acc atc gtg tgt gtg gcg aat aaa tac ttt
L
K01362 IGKC1*02 F -tt --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
E L A
K01363 IGKC1*03 F g-- c-- --- ... ... ... --- --- --- -c- --- --- --- --c --- --a --c --- --- ---
L T E F R
X00674 IGKC1*04 F --- c-- a-- ... ... ... --- -a- --- --- --- --- --- --c --- --a --- --- -t- cg-
L T E F R
X03050 IGKC1*05 ORF (1) --- c-- a-- ... ... ... --- -a- --- --- --- --- --- --c --- --a --- --- -t- cg-
E L A
M37809 IGKC1*06 F g-- c-- --- ... ... ... --- --- --- -c- --- --- --- --c --- --- --- --- --- ---
E L A
M22542 IGKC1*07 F g-- c-- --- ... ... ... --- --- --- -c- --- --- --- --c --- --- --- --- --- ---
E L A
Z48308 IGKC1*08 F g-- c-- --- ... ... ... --- --- --- -c- --- --- --- --c --- --- --- --- --- ---
L T E F R
K01359 IGKC1*09 (F) (cDNA) --- c-- a-- ... ... ... --- -a- --- --- --- --- --- --c --- --a --- --- -t- cg-
___________BC______________ _____________CD_________
45.1 45.3 45.5
30 31 34 35 36 37 38 39 40 41 42 43 44 45 45.2 45.4 45.6
P D V T V T W E V D G T T Q T T
K01360 IGKC1*01 F ccc ... ... ... gat gtc acc gtc acc tgg gag gtg gat ggc acc acc caa aca act ...
K01362 IGKC1*02 F --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
G Q K P L
K01363 IGKC1*03 F --- ... ... ... --- -g- --- --- --- --- c-- --- --- --- -ag c-- -t- --- --- ...
N I K V E I Q S
X00674 IGKC1*04 F --- ... ... aat --c a-- --- --- --- --- a-- --- --- -t- gaa -t- --- cag -gc ...
N I K D E I Q S
X03050 IGKC1*05 ORF (1) --- ... ... aat --c a-- --- --- --- --- a-- --- --- -a- gaa -t- --- cag -gc ...
G K I S S
M37809 IGKC1*06 F --- ... ... ... --- -g- --- --- --- --- a-- --- --- --- -t- --- --- -gc -gc ...
K
M22542 IGKC1*07 F --- ... ... ... --- --- --- --- --- --- a-- --- --- --- --- --- --- --- --- ...
G K I S S
Z48308 IGKC1*08 F --- ... ... ... --- -g- --- --- --- --- a-- --- --- --- -t- --- --- -gc -gc ...
N I K D E I Q S
K01359 IGKC1*09 (F) (cDNA) --- ... ... aat --c a-- --- --- --- --- a-- --- --- -a- gaa -t- --- cag -gc ...
____ ___________________________DE_______________
45.7 84.1 84.3 84.5 84.7 85.6 85.4
77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
G I E N S K T P Q N S A D C
K01360 IGKC1*01 F ... ggc atc gag aac agt aaa aca ccg cag aat tct gca gat ... ... ... ... ... tgt
K01362 IGKC1*02 F ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ---
T D
K01363 IGKC1*03 F ... --- --- --- -c- --- --- --- --- --- --- --- -at --- ... ... ... ... ... ---
T S P E
X00674 IGKC1*04 F ... --- --- --- --- --- -c- --- --- --- -gc c-c -a- --c ... ... ... ... ... ---
T S P E
X03050 IGKC1*05 ORF (1) ... --- --- --- --- --- -c- --- --- --- -gc c-c -a- --c ... ... ... ... ... ---
N R
M37809 IGKC1*06 F ... --- --- a-t --- --- -g- --- --- --- --- --- --- --- ... ... ... ... ... ---
R D
M22542 IGKC1*07 F ... --- --- --- --- --- -g- --- --a --- --- --- -at --- ... ... ... ... ... ---
N R D P T Y
Z48308 IGKC1*08 F ... --- --- a-t --- --- -g- --- --- --- g-- c-- a-- t-- ... ... ... ... ... ---
T S P E
K01359 IGKC1*09 (F) (cDNA) ... --- --- --- --- --- -c- --- --- --- -gc c-c -a- --c ... ... ... ... ... ---
____________ ___EF___
85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98 99
T Y N L S S T L T L T S T Q Y N S H
K01360 IGKC1*01 F acc tac aac ctc agc agc act ctg aca ctg acc agc aca cag tac ... ... aac agc cac
K01362 IGKC1*02 F --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
K D E
K01363 IGKC1*03 F --- --- --- --- --- --t --- --- --- --- -aa --- gac g-- --- ... ... --- --- ---
S K A
X00674 IGKC1*04 F --- --- --- --- --- --- --- --- t-- --- --- -aa g-- --- --- ... ... --- --- ---
S K A
X03050 IGKC1*05 ORF (1) --- --- --- --- --- --- --- --- t-- --- --- -aa g-- --- --- ... ... --- --- ---
S D E
M37809 IGKC1*06 F --- --- --- --- --- --t --- --- --- --- -g- --- gac g-- --- ... ... --- --- ---
K D E
M22542 IGKC1*07 F --- --- --- --- --- --t --- --- --- --- -aa --- gac g-- --- ... ... --- --- ---
S D E
Z48308 IGKC1*08 F --- --- --- --- --- --t --- --- --- --- -g- --- gac g-- --- ... ... --- --- ---
S K A
K01359 IGKC1*09 (F) (cDNA) --- --- --- --- --- --- --- --- t-- --- --- -aa g-- --- --- ... ... --- --- ---
_________________________FG________________________
100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119
K E Y T C K V T Q G T T S V V Q
K01360 IGKC1*01 F aaa gag tac acc tgc aag gtg acc cag ggc ... ... ... ... acg acc tca gtc gtc cag
K01362 IGKC1*02 F --- --- --- --- --- --- --- --- --- --- ... ... ... ... --- --- --- --- --- ---
D Q A S G S P
K01363 IGKC1*03 F g-c --- --- --- --- c-- --- g-- --- --- ... ... ... tca ggc t-a c-g --- --- ---
S V E V H N S G S A I
X00674 IGKC1*04 F -gc -t- --- --- --- g-- --- gt- --c aa- ... ... ... tcg ggc t-a g-g a-- --- ---
S V E V H N S G S A I
X03050 IGKC1*05 ORF (1) -gc -t- --- --- --- g-- --- gt- --c aa- ... ... ... tcg ggc t-a g-g a-- --- ---
D Q A D S G S P
M37809 IGKC1*06 F g-c --- --- --- --- c-- --- g-- --- -a- ... ... ... tca ggc t-a c-g --- --- ---
D I Q A S G S P
M22542 IGKC1*07 F g-c --- --- -t- --- c-- --- g-- --- --- ... ... ... tca ggc t-a c-g --- --- ---
N Q A D S G S P
Z48308 IGKC1*08 F --c --- --- --- --- c-- --- g-- --- -a- ... ... ... tca ggc t-a c-g --- --- ---
S V E V H N S G S A I
K01359 IGKC1*09 (F) (cDNA) -gc -t- --- --- --- g-- --- gt- --c aa- ... ... ... tcg ggc t-a g-g a-- --- ---
120 121 122 123 124 125 126
S F N R G D C
K01360 IGKC1*01 F agc ttc aat agg ggt gac tgt
K01362 IGKC1*02 F --- --- --- --- --- --- ---
S K N
K01363 IGKC1*03 F --- --- -g- --- aag a-- ---
X00674 IGKC1*04 F --- --- --- --- --- --- ---
X03050 IGKC1*05 ORF (1) --- --- --- --- --- --- ---
S K S
M37809 IGKC1*06 F --- --- -g- --- aag ag- ---
S K N
M22542 IGKC1*07 F --- --- -g- --- aag a-- ---
K S
Z48308 IGKC1*08 F --- --- --- --- aag ag- ---
K01359 IGKC1*09 (F) (cDNA) --- --- --- --- --- --- ---
1.8 1.7 1.6 1.5 1.4 1.3 1.2 1.1 1 2 3 4 5 6 7 8 9 10 11 12
R D P V A P S V L L F P P S K E
X00232 IGKC2*01 F ... ... ... ... cgt gat cca gtt gcg cct tct gtc ctc ctc ttc cca cca tct aag gag
X05800 IGKC2*02 F ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X56061 IGKC2*03 F (2) ... ... ... ... --- --- --- --- --a --- --- --- --- --- --- --- --- --- --- ---
M22543 IGKC2*03 F ... ... ... ... --- --- --- --- --a --- --- --- --- --- --- --- --- --- --- ---
K01280 IGKC2*04 (F) (3) ... ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---
_____AB_____ ____________
15.1 15.3
13 14 15 15.2 16 17 18 19 20 21 22 23 24 25 26 27 28 29
E L T T G T A T I V C V A N K F Y
X00232 IGKC2*01 F gag ctg aca ... ... ... act gga aca gcc acc atc gtg tgc gtg gcg aat aaa ttc tat
X05800 IGKC2*02 F --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
X56061 IGKC2*03 F (2) --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
K01280 IGKC2*04 (F) (3) --- --- --- ... ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- ---
___________BC_______________ _____________CD_________
45.1 45.3 45.5
30 31 34 35 36 37 38 39 40 41 42 43 44 45 45.2 45.4 45.6
P S D I T V T W K V D G T T Q Q S
X00232 IGKC2*01 F ccc ... ... agt gac atc acc gtc acc tgg aag gtg gat ggc acc acc caa cag agc ...
X05800 IGKC2*02 F --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
X56061 IGKC2*03 F (2) --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
K01280 IGKC2*04 (F) (3) --- ... ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ...
____ ___________________________DE_______________
45.7 84.1 84.3 84.5 84.7 85.6 85.4
77 78 79 80 81 82 83 84 84.2 84.4 84.6 85.7 85.5
G I E N S K T P Q S P E D N
X00232 IGKC2*01 F ... ggc atc gag aac agt aaa aca ccg cag agc ccc gaa gac ... ... ... ... ... aat
X05800 IGKC2*02 F ... --- --- --- --- --- --- --- --- --- --- --t --- --- ... ... ... ... ... ---
X56061 IGKC2*03 F (2) ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ---
K01280 IGKC2*04 (F) (3) ... --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ---
____________ ___EF___
85.2 96.1
85.3 85.1 85 86 87 88 89 90 91 92 93 94 95 96 96.2 97 98 99
T Y S L S S T L S L T S A Q Y N S H
X00232 IGKC2*01 F acc tac agc ctg agc agc act ctg tca ctg acc agc gca cag tac ... ... aac agc cac
X05800 IGKC2*02 F --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
X56061 IGKC2*03 F (2) --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
K01280 IGKC2*04 (F) (3) --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... ... --- --- ---
_________________________FG________________________
100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119
S V Y T C E V V Q G S A S P I V Q
X00232 IGKC2*01 F agc gtg tac acc tgc gag gtg gtc caa ggc tca ... ... ... gcc tca ccg atc gtc cag
X05800 IGKC2*02 F --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- --- --- --- --- ---
X56061 IGKC2*03 F (2) --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- --- --- --- --- ---
L
K01280 IGKC2*04 (F) (3) --- --- --- --- --- --- --- --- --- --- --- ... ... ... --- --- -t- --- --- ---
120 121 122 123 124 125 126
S F N R G D C
X00232 IGKC2*01 F agc ttc aac agg ggt gac tgc
V00885 IGKC2*01 F --- --- --- --- --- --- ---
X05801 IGKC2*01 F --- --- --- --- --- --- ---
X05800 IGKC2*02 F --- --- --- --- --- --- ---
X56061 IGKC2*03 F (1) --- --- --- --- --- --- ---
M22543 IGKC2*03 F --- --- --- --- --- --- ---
K01280 IGKC2*04 (F) (2) --- --- --- --- --- --- ---
| (1) | The strain is Basilea. ORF because of non canonical ACCEPTOR-SPLICE sequence: naann instead of nagnn. |
| (2) | This allele was identified in the subspecies sp.algirus. |
| (3) | This allele was identified in the strain : Basilea. |
Created: 30/04/2010
Authors: Fatena Bellahcene
Editor: Chantal Ginestoux
Contact: Marie-Paule Lefranc
Authors: Fatena Bellahcene
Editor: Chantal Ginestoux
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only,
provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics
information system® http://www.imgt.org
(founder and director: Marie-Paule Lefranc, Montpellier, France)."
References to cite:
Lefranc, M.-P. et al.,
Nucleic Acids Research, 27, 209-212 (1999)
Cover of NAR;
Ruiz, M. et al.,
Nucleic Acids Research, 28, 219-221 (2000);
Lefranc, M.-P.,
Nucleic Acids Research, 29, 207-209 (2001);
Lefranc, M.-P.,
Nucleic Acids Res., 31, 307-310 (2003);
Lefranc, M.-P. et al.,
In Silico Biol., 5, 0006 (2004) [Epub],
5, 45-60 (2005);
Lefranc, M.-P. et al.,
Nucleic Acids Res., 33, D593-D597 (2005)
Full text;
Lefranc, M.-P. et al.,
Nucleic Acids Research 2009 37:
D1006-D1012; doi:10.1093/nar/gkn838
Full text.
For any other use please contact Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr.
IMGT founder and director: Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
Bioinformatics manager: Véronique Giudicelli
Veronique.Giudicelli@igh.cnrs.fr
Computer manager: Patrice Duroux
Patrice.Duroux@igh.cnrs.fr
Webmaster: Chantal Ginestoux
Chantal.Ginestoux@igh.cnrs.fr
Citing IMGT | Warranty disclaimer and copyright notice | Privacy policy and advertisement policy
© Copyright 1995-2012 IMGT®, the international ImMunoGeneTics information system®