IMGT Repertoire (IG and TR)

Alignment of alleles: Rabbit (Oryctolagus cuniculus) IGKV1S1

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

                                    
                                    
      
                                     1   2   3   4   5   6   7   8   9   10  11  12  13  14  15  16  17  18  19  20 
                                     A   L   V   M   T   Q   T   P   S   P   V   S   A   A   V   G   G   T   V   T 
  K02131   IGKV1S1*01 F (1)         gcg ctt gtg atg acc cag act cca tcc cct gtg tct gca gct gtg gga ggc aca gtc acc


                                                            ___________________CDR1-IMGT____________________        
                                    
                                     21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40 
                                     I   S   C   Q   S   S   E   S   V   Y                   S   N   N   R   L   S 
  K02131   IGKV1S1*01 F (1)         atc agt tgc cag tcc agt gag agc gtt tat ... ... ... ... agt aac aac cgc tta tcc


                                                                                                _______________CDR2-
                                    
                                     41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59  60 
                                     W   F   Q   Q   K   P   G   Q   P   P   K   L   L   I   Y   T   A             
  K02131   IGKV1S1*01 F (1)         tgg ttt cag cag aaa cca ggg cag cct ccc aag ctc ctg atc tat act gca ... ... ...


                                    IMGT________________                                                            
                                    
                                     61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79  80 
                                                     S   S   L   A   S   G   V   P       S   R   F   K   G   S   G 
  K02131   IGKV1S1*01 F (1)         ... ... ... ... tcc agt ctg gca tct ggg gtc cca ... tcg cgg ttc aaa ggc agt gga


                                    
                                    
                                     81  82  83  84  85  86  87  88  89  90  91  92  93  94  95  96  97  98  99 100 
                                             S   G   T   Q   F   T   L   T   I   S   G   V   E   C   D   D   A   A 
  K02131   IGKV1S1*01 F (1)         ... ... tct ggg aca cag ttc act ctc acc atc agt ggc gtg gag tgt gac gat gct gcc


                                                    _________________CDR3-IMGT__________________
                                    
                                    101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 
                                     T   Y   Y   C   A   G   Y   K   S   Y   S   K   *   *   Y  
  K02131   IGKV1S1*01 F (1)         act tac tac tgt gca ggc tat aaa agt tat agt aag tga tga tac

Legend:

*: STOP_CODON mutation

IMGT note:
(1)	Functional because of two STOP-CODONs in CDR3-IMGT which may disappear during rearrangements.

Created: 03/05/2010
Author: Fatena Bellahcene
Editor: Chantal Ginestoux
Contact: Marie-Paule Lefranc

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