Only the *01 allele of each functional, ORF and in-frame pseudogene V-REGION is shown.
Dots indicate gaps according to the IMGT unique numbering. Blanks at the 5' and/or 3' end indicate partial sequences.
Two pseudogenes IGHV1S7 (1) and IGHV1S8 (2) have been included .
________________________________________________________________________________________________________________________________________________ IGHV FR1-IMGT CDR1-IMGT FR2-IMGT CDR2-IMGT FR3-IMGT CDR3-IMGT gene (1-26) (27-38) (39-55) (56-65) (66-104) (105-115) ________________________ __________________________ ____________ _________________ __________ _______________________________________ ___________ 1 10 20 30 40 50 60 70 80 90 100 110 .........|.........|...... ...|........ .|.........|..... ....|..... ....|.........|.........|.........|.... .....|..... AF305944,IGHV1S1 QVQLVESGG.GLVQPGGSLRLSCAAS GFTLDYYA.... IGWFRQAPGKEREGVSC ISSSDGST.. YYADSVK.GRFTISRDNAKNTVYLQMNSLKPEDTAVYYC AA......... AF305945,IGHV1S2 QVQLVESGG.GLVQPGGSLRLSCAAS GFTLDDYA.... IGWFRQAPGKEREGVSC ISSSDGST.. YYADSVK.GRFTISRDNAKNTLYLQMNSLKPEDTAVYYC AA......... AF305946,IGHV1S3 QVQLVESGG.GLVQAGGSLRLSCAAS GDTICISA.... MGWYRQAPGKERELVAA ITSGGST... NYADSVK.GRFTISRDNAKNTVYLQMNSLKPEDTAVYYC NA......... AF305947,IGHV1S4 QVQLVESGG.GLVQAGGSLRHSCAAS GLTFGSYA.... MGWYRQAPGKERELVAA ISSGGST... YYADSVK.GQFTISRDNAKNTLYLQMNSLKPGDTAVYYC AK......... AF305948,IGHV1S5 QVQLVESVG.GLVQDGGSLRLSCAAS GRTFSRSA.... MRWFRQAPGKEREWVSC ISSSDGST.. NYADSVK.ARFTISRDNAKNTLYLQMNSLKPEDTAVYYC A.......... AF305949,IGHV1S6 EVQLVESGG.GLVQPGGSLRLSCAAS GFTFSSSA.... MSWVRQAPGKGLEWVSS IYSYSSNT.. YYADSVK.SRFTISTDNAKNTLYLQMNSLKPEDTAVYYC AA......... AF305950,IGHV1S7 (1) EVQLVESGG.GLVQPGGSLRLSCAAS GFTFDDYG.... MSWV*QAPGKGLEWVSA ISGNGGST.. YYAESMK.GRFTISRDNAKNTLYLQMNSLKSEDTAVYYC AK......... AF305951,IGHV1S8 (2) EVQLVESGG.GLVQPGGSLRRSCATS GFTFGSYW.... MYWVRQAPGKGLEWVST INTGGDSS.. YYADSVK.GRFTISRDNAKNTLYLQMNSLKPEDTAVY*C VR.........
IMGT notes:
| (1) | In frame STOP-CODON (positions 127-129) at codon 43 in FR2-IMGT. |
| (2) | In frame STOP-CODON (positions 307-309) at codon 103 in FR3-IMGT. |
Created: 05/02/2002
Author: Dominique Scaviner
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
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IMGT founder and director: Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
Bioinformatics manager: Véronique Giudicelli Veronique.Giudicelli@igh.cnrs.fr Computer manager: Patrice Duroux Patrice.Duroux@igh.cnrs.fr Webmaster: Chantal Ginestoux Chantal.Ginestoux@igh.cnrs.fr |
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Citing IMGT © Copyright 1995-2012 IMGT®, the international ImMunoGeneTics information system® |
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