Only the *01 allele of each functional, ORF and in-frame pseudogene V-REGION is shown.
Dots indicate gaps according to the IMGT unique numbering. Blanks at the 5' and/or 3' end indicate partial sequences.
_________________________________________________________________________________________________________________________________________________
IGHV FR1-IMGT CDR1-IMGT FR2-IMGT CDR2-IMGT FR3-IMGT CDR3-IMGT gene (1-26) (27-38) (39-55) (56-65) (66-104) (105-115) ______________________ __________________________ ____________ _________________ __________ _______________________________________ ___________ 1 10 20 30 40 50 60 70 80 90 100 110 .........|.........|...... ...|........ .|.........|..... ....|..... ....|.........|.........|.........|.... .....|..... #c M29672 ,IGHV1S1 AVVLNQKPT.EAAKSGESLKLTCVTS GFSLSSSN.... VHWVKQVPGKGLEWVAI MWYDDDK... DYAPAFS.GRFTVSR..DSSNVYLQMTNLSLADTATYYC A #c M29679 ,IGHV1S2 DIVLTQPET.ETATPGGSITLNCKIS GFTVGSQW.... MALVRQVPGQGLEWLLH YHSPGNE... QFAPGIK.SRFTPSNDKTNNIFIVTASSLKIEDTAVYYC AR X15124 ,IGHV1S3 DIVLTQPKT.EAATPGGSITLTCKVS GFALSSYA.... MHLVRQAPGQGLEWLLR YFSSSNK... QFAPGIE.SRFTPSTDHSTNIFTVIARNLKIEDTAVYYC AR ~VD X15125 ,IGHV1S4 EIVLTQPKT.GTAVPGGSITLTCKTS GFTLSSYY.... IYLVRQVPGQGLEWLLT YHASATN... YFAPGIE.SRFTPSTDNSNNMFTVIARNLKIEDTAVYYC A ~VD,DJ X16146,IGHV1S5 DVVLTQPKT.GTAVPGGSITLTCKTS GFTLSSYY.... MYLIRQVPGQGLEWLLA YHAPTTTV.. YFAPGIE.SRFTPSKDNSNNMFTVIARNLKIEDTDVYYC AR
#c: rearranged cDNA
~VD,DJ: VD,DJ genomic DNA rearranged in the cassette.
~VD: VD genomic DNA rearranged in the cassette.
Created: 17/05/2001
Last updated:Monday, 11-Jul-2011 12:57:01 CEST
Authors: Lorena Betancourt and Dominique Scaviner
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
|
IMGT founder and director: Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
Bioinformatics manager: Véronique Giudicelli Veronique.Giudicelli@igh.cnrs.fr Computer manager: Patrice Duroux Patrice.Duroux@igh.cnrs.fr Webmaster: Chantal Ginestoux Chantal.Ginestoux@igh.cnrs.fr |
|
|
|
|
Citing IMGT © Copyright 1995-2012 IMGT®, the international ImMunoGeneTics information system® |
|||
