Only the *01 allele of each functional, ORF and in-frame pseudogene V-REGION is shown.
Dots indicate gaps according to the IMGT unique numbering. Blanks at the 5' and/or 3' end indicate partial sequences.
_________________________________________________________________________________________________________________________________________________ IGHV FR1-IMGT CDR1-IMGT FR2-IMGT CDR2-IMGT FR3-IMGT CDR3-IMGT gene (1-26) (27-38) (39-55) (56-65) (66-104) (105-115) ________________________ __________________________ ____________ _________________ __________ ________________________________________ ___________(1): The translation in the flat files is different from that published in Fig.2 in Immunology and Cell Biology, 74, 357-364, (1996) PMID: 8872187. Amino acid sequences shown in that Protein display were corrected by IMGT. The typing errors in the flat files are the following:
1 10 20 30 40 44A 50 60 70 71A 80 90 100 110
.........|.........|...... ...|........ .|..........|..... ....|..... ....|..........|.........|.........|.... .....|.....
#c U40560 ,IGHV1S1 DIVLTQPES.VVKKPGETVRLSCGVT GFDIDTHY.... ITWVKQ.VPGKGLEWLLY HDSRPQ.... EFAPGI.E.GRFTPSV..VSNTAYLEITSLSVTDTAIYYC AR
#c U50604 ,IGHV1S2 DIVLTQPES.VVKKPGETVRLSCAVS GFDIARVY.... ISWVKQ.GPGKGLEWLLY HDSRPQ.... GFAPGI.E.GRFSPSA..VSNTAYIEITSLRADDTAIYYC AR
#c U50605 ,IGHV1S3 DIVLTQPEG.VVKKPGETVRLSCAVS GFDIDSTY.... ISWVKQ.VPGKGLEWLLY HDSKPQ.... GFAPGI.E.GRLTPSV..VTNTAYIEITSLRVDDTATYYC AR
#c U50606 ,IGHV1S4 DIVLTQPES.VLKKPGETVRLSCAVS GFALDSTY.... MSWVKQ.DPGKGLEWLLY HDSSPQ.... GFAPGI.E.GRFTPSA..VSNTAYIEITNLRVDDTAIYYC AR
#c U50607 ,IGHV1S5 DIVLTQPES.VVKKSGETVRLSCAVR GFNIDSTF.... INWVKQ.VPGEGLEWLLY QDASPQ.... GFTPGI.E.GRFTPSV..VGSTAYIEITSLTTDDTAIYYC AR
#c U50608 ,IGHV1S6 DIVLTQPES.VVKKPGETVRLSCTVT GFEIDHTY.... ISWVKQ.VPGKGLEWLLN HDINPQ.... NFAPGI.E.GRFTPSV..ISNTAYLEITSLTTDDTAIYYC TR
#c U50609 ,IGHV1S7 DIVLTQPES.VVKKPGETVRLSCGIS GFDIDTHY.... ITWVKQ.VPGKGLEWLLY HDSRPQ.... EFAPGI.E.GRFTPSV..VSNTAYLEITRLSMPDTAIYYC AR
#c U50610 ,IGHV1S8 DIVLTQPES.VVNKPGETVRLSCGVS GFNIDTHY.... ISWVKQ.GPGKGLEWLLY HDSRSQ.... EFAPGI.E.GRFIPSV..VSNTAYLETARASAPDSAIYYC AR
#c AY548346 ,IGHV2S1 DVVLTQPDE.ETGHPEDSLKLTCSTS GFKLANYW.... MGWIRQ.VPGQGLEWLVS YYSTESNYY. VPSIQG.R.FTASKDT..SNNMFSLHMTTLKTEDTAIYYC AR
#c AY548347 ,IGHV2S2 DVVLTQPDE.ETGRPGRSLKLTCKTS AFRLRRAST... MSWIRQAVPGQGLVWLVS FYSSSYEYY. APGIQG.R.FTASKDT..SNNIFSLNMRTLKIEDTAIYYC AR
#c AY548348 ,IGHV2S3 DVVLTQPDE.ETGHPGDSLKLTCSTS GFKLANYW.... MGWIRQ.VPGQGLEWLVS YYSTESNYY. EPSIQG.R.FTTSKDT..SNNMFSLHMTTLKTEDTAIYYC AR
#c AY548349 ,IGHV2S4(1) DIVLTQPEA.ETGHPGGSLKLTCKTS GFDLSGKY.... MSWIRQ.VPGQGLEWLVS YRSKSNEYY. APGIQG.R.FTASKEI..SNNIFSLDMRTLKIEDTAIYYC VR
#c AY548350 ,IGHV2S5 DVVLTQ.....TGRPGGSLKLTCKTS GFDLNNDW.... MGWIRQ.VPGQGLEWLVS YHHSASSNY. APSIQG.R.YTASKDT..INNIFSLDMTNLKIEDTATYFC AR
#c AY548351 ,IGHV2S6 DVVLTQNEA.ETGRPGGSLKLTCKTS GFSLSGYW.... MFWIRQ.VPGQGLEWLVS CATSSNSNY. APSIQGSR.FHASKDT..TNNIFSLDMRSLTIEDSAIYYC AR
#c AY548352 ,IGHV2S7 GIRLTQPEA.ETGHPGGSLKLTCKTS GFNLGSYF.... ICWIRQ.VPGQGLEFLTS YLNSDNNYY. VPSIQG.R.FTASKDT..SNNIFSLDEDALTLEDTAIYYC AR
#c AY548353 ,IGHV2S8 DVVLTQPDE.ETGRPGGSLKLTCKTS GFDLSNYW.... MGWIRQ.VPGQGLEWLVS YHSSDHTNY. APSIQG.R.FTASKDT..SNNIFSLDMTSLKIEDTATYYC AR
#c AY548354 ,IGHV2S9 DVVLTQPDE.ETGRPGGSLKLTCKTS GFDLSNYW.... MGWIRQ.VPGQGLEWLVS YHSSDHSNY. APSIQG.R.FTASKDT..SNNIFSLDMTSLKIEDTATYYC AR
#c AY548357 ,IGHV2S10 DIVLTQPDE.ETGRPGGSLKLTCKTS GFDLSGKY.... MSWIRQ.VPGQGLEWLVS YRSKSNEYY. APGILG.R.FTASKEI..SNNIFSLDMRTLKIEDTAYYYC VA
#c AY548358 ,IGHV2S11 DVVLTQPDE.ETGRPRGSLKLTCKTS GFDLSNSY.... IGWIRQ.VPGQGLEWLAS ISSSGSSYY. APSNSG.S.IYCVQNT..SNTSFLLDMTSLKIEDTAIYYC AR
#c AY548359 ,IGHV2S12(1) EIVLTQPDA.ETGRPGGSLKLTCKTS GFNLGGYW.... MFWVRQ.LPGMGLEWLVS CATSSNSNY. LAINSA.R.FTASKDT..TNNIFSLDMRSLTIEDSAIYYC AR
#c AY548360 ,IGHV2S13 DVVLTQPDE.ETGHPGSSLRLTCKTS GFSLSHVL.... DGWIRQ.VPGQGLEWLAS CYTLGGSYY. APSIQG.R.FTASKDT..ANNIFSLDMTTLKIEDTAIYYC AR
#c AY548361 ,IGHV2S14 DVVLTQNEA.ETGRPGGSLKLTCKTS GFDLSGYW.... MFWIRQ.VPGQGLEWLVS CATSSNSNY. LAINSA.R.FTASKDT..TNNIFSLDMRSLTIEDSAIYYC AR
#c AY548355 ,IGHV3S1(1) EIVLTQPDA.ETGRPRGSLKLNCKTS GFNLGSNY.... MFWVRQ.LPGMGLEWLLY YYSSSGIGT. TSIIKG.R.FTATKDT..SNNIFSLEMTSLNFDDESIYYC AT
#c AY548356 ,IGHV4S1 VIVLAQPER.ETGHPGGSLRLTCKTS GFDLNELR.... MGWIRQ.VTGPGVADYLA SNHCDLL... SRTSSG.I.GLLSADT..SNNIFSLDMTSLKIEDTAMYYC AL
#c AY548362 ,IGHV5S1 QVVLMQVEK.ATGHVGDSLRLTCKTS GFTLENAW.... MSWIRE.LPGQGLEWLVS YFEENDNYY. ALGIQS.R.FTASKDL..SNNIFALSMTRLRFEDTAIYYC AI In italics, IMGT corrected translations.
#c: rearranged cDNA
Created: 06/07/2000
Last updated: Wednesday, 29-Jun-2011 17:05:54 CEST
Authors: Dominique Scaviner, Joumana Jabado Michaloud and Lorena Betancourt
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
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