The protein display numbering is according to the IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.
Only the C-DOMAIN of the *01 allele of each functional or ORF C-REGION is shown.
Letters in red correspond to amino acids which are polymorphic in the other alleles.
For C-REGIONs, letters in bold correspond to additional positions in the IMGT unique numbering.
For C-REGIONs, letters between parentheses correspond to amino acids resulting from the splicing.
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CH-S and in pages edited before 14/10/2009).
Protein displays of the complete C-REGIONs is available in IMGT Repertoire.
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TR-C
genes
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A AB B BC C CD D DE E EF F FG G CH-S
--------------> ----------> ------> -------> -----------> -------> ---------->
1 10 15 16 20 23 30 36 39 41 45 77 84 85 89 96 97 104 110 118 121 130 140 150
7654321|........|....|123|...|...... ...|.....| |.....|1234567|......|12345677654321|..........|12|....... .....|....... ..|.........|.........|.........|
EX1
Homsap X02883 ,TRAC (1) (N)IQNPDPAVYQLRDSK......SSDKSVCLFT DFDS...QTN VSQSKDS.......DVYITDKTVLDMRSM.DFKSNSAVAWSNKS..........DFAC ANAFNN..............SIIPE DTFFPSP
Musmus M64239 ,TRAC (D)IQNPEPAVYQLKDPR......SQDSTLCLFT DFDS...QIN VPKTMES.......GTFITDKTVLDMKAM.DSKSNGAIAWSNQT..........SFTC QDIFKE.............TNATYP SSGFEWCPR
Homsap M12887 ,TRBC1 (E)DLNKVFPPEVAVFEPSEAEISH..TQKATLVCLAT GFFP..DHVE LSWWVNGKEVHS..GVSTDPQPLKEQPAL.NDSRYCLSSRLRVSATFWQ.NPRNHFRC QVQFYGLSENDEWTQDRAKPVTQIV SAEAWGRA
Homsap M12888 ,TRBC2 (E)DLKNVFPPEVAVFEPSEAEISH..TQKATLVCLAT GFYP..DHVE LSWWVNGKEVHS..GVSTDPQPLKEQPAL.NDSRYCLSSRLRVSATFWQ.NPRNHFRC QVQFYGLSENDEWTQDRAKPVTQIV SAEAWGRA
Musmus X02384 ,TRBC1 (E)DLRNVTPPKVSLFEPSKAEIAN..KQKATLVCLAR GFFP..DHVE LSWWVNGKEVHS..GVSTDPQAYKESN.....YSYCLSSRLRVSATFWH.NPRNHFRC QVQFHGLSEEDKWPEGSPKPVTQNI SAEAWGRA
Musmus M26057 ,TRBC2 (E)DLRNVTPPKVSLFEPSKAEIAN..KQKATLVCLAR GFFP..DHVE LSWWVNGKEVHS..GVSTDPQAYKESN.....YSYCLSSRLRVSATFWH.NPRNHFRC QVQFHGLSEEDKWPEGSPKPVTQNI SAEAWGRA
Homsap M22148 ,TRDC (R)SQPHTKPSVFVMKNG.......TNVACLVK EFYP..KDIR INLVSSKKITEF..DPAIVISPSG..........KYNAVKLGKYED......SNSVTC SVQHDN.............KTVHST DFEVKTDST
Musmus M23381 ,TRDC (E)SQPPAKPSVFIMKNG.......TNVACLVK DFYP..KEVT ISLRSSKKIVEF..DPAIVISPSG..........KYSAVKLGQYGD......SNSVTC SVQHNSE.............TVHST DFEPYANSF
Homsap M14996 ,TRGC1 (D)KQLDADVSPKPTIFLPSIAETKL..QKAGTYLCLLE KFFP..DVIK IHWQEKKSNTIL..GSQEGNTMKTND.......TYMKFSWLTVPEK....SLDKEHRC IVRHENN............KNGVDQ EIIFPPIKT
Homsap M15002 ,TRGC2(2x) (D)KQLDADVSPKPTIFLPSIAETKL..QKAGTYLCLLE KFFP..DIIK IHWQEKKSNTIL..GSQEGNTMKTND.......TYMKFSWLTVPEE....SLDKEHRC IVRHENN............KNGIDQ EIIFPPIKT
c Homsap M17323 ,TRGC2(3x) (D)KQLDADVSPKPTIFLPSIAETKL..QKAGTYLCLLE KFFP..DIIK IHWQEKKSNTIL..GSQEGNTMKTND.......TYMKFSWLTVPEE....SLDKEHRC IVRHENN............KNGIDQ EIIFPPIKT
Musmus M13340 ,TRGC1 (A)KRLDADISPKPTIFLPSVAETNL..HKTGTYLCLLE KFFP..DVIR VYWKEKDGNTIL..DSQEGDTLKTND.......TYMKFSWLTVPER....AMGKEHRC IVKHENN............KGGADQ EIFFPSIKK
Musmus M12834 ,TRGC2 (D)KRLDADISPKPTIFLPSVAETNL..HKTGTYLCLLE KFFP..DVIR VYWKEKNGNTIL..DSQEGDTLKTKG.......TYMKFSWLTVPER....AMGKEHSC IVKHENN............KGGADQ EIFFPSIKK
Musmus M12837 ,TRGC3 (D)KKLDADISPKPTIFLPSVAETNL..HKTGTYLCVLE KFFP..DVIR VYWKEKKGNTIL..DSQEGDMLKTND.......TYMKFSWLTVPER....SMGKEHRC IVKHENN............KGGADQ EIFFPTIKK
Musmus AF021335,TRGC4 (D)KRTDSDFSPKPTIFLPSAAETNL..HKAGTYLCLLE KFFP..EVIR VYWKEKDGEKIL..ESQEGNTIKTND.......RYMKFSWLTVTED....SMAKEHSC IVKHENN............KRGVDQ EILFPPIGK
c: cDNA sequenceIMGT note:
| (1) | The first amino acid of the TRA C-REGION which results from the splicing with the J-REGION is N (codon aat), D (codon gat), Y (codon tat) or H (codon cat) for 35, 12, 7 and 4 TRAJ, respectively. See Alignment of alleles: Human TRAJ (overview) for the sequences of the 58 FUNCTIONAL and ORF TRA J-REGION. |
Homsap: Homo sapiens (Human)
Musmus: Mus musculus (House mouse)
Created: 02/05/2003
Author: Delphine Guiraudou
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
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IMGT founder and director: Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
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