Protein display: Human IGL C-REGIONs

The IGLC protein display numbering is according to the IMGT unique numbering for C-DOMAIN.

_____________________________________________________________________________________________________________________________________________________________________________________________

      IGLC
      genes
_____________________________________________________________________________________________________________________________________________________________________________________________
                                 A        AB     B          BC         C      CD     D          DE           E      EF   F            FG          G
                          -------------->   ---------->             ------>       ------->              ----------->  ------->               ----------->
                          1       10   15  16  20 23      30    36 39 41 45      77     84             85  89     96 97    104    110      118  121    130
                   7654321|........|....|123|...|...... ...|.....|  |.....|1234567|......|12345677654321|..........|12|....... .....|....... ..|.........|

  X51755  ,IGLC1   (G)QPKANPTVTLFPPSSEELQ...ANKATLVCLIS DFYP..GAVT  VAWKADGSPVKA..GVETTKPSKQSN......NKYAASSYLSLTPEQW..KSHRSYSC QVTHE....GSTV EKTVAPTECS
  J00253  ,IGLC2   (G)QPKAAPSVTLFPPSSEELQ...ANKATLVCLIS DFYP..GAVT  VAWKADSSPVKA..GVETTTPSKQSN......NKYAASSYLSLTPEQW..KSHRSYSC QVTHE....GSTV EKTVAPTECS
  X06876  ,IGLC3(1)(G)QPKAAPSVTLFPPSSEELQ...ANKATLVCLIS DFYP..GAVT  VAWKADSSPVKA..GVETTTPSKQSN......NKYAASSYLSLTPEQW..KSHKSYSC QVTHE....GSTV EKTVAPTECS
  J03011  ,IGLC6(2)(G)QPKAAPSVTLFPPSSEELQ...ANKATLVCLIS DFYP..GAVK  VAWKADGSPVNT..GVETTTPSKQSN......NKYAASSYLSLTPEQW..KSHRSYSC QVTHE....GSTV EKTVAPAECS
  X51755  ,IGLC7   (G)QPKAAPSVTLFPPSSEELQ...ANKATLVCLVS DFYP..GAVT  VAWKADGSPVKV..GVETTKPSKQSN......NKYAASSYLSLTPEQW..KSHRSYSC RVTHE....GSTV EKTVAPAECS
IMGT notes:
(1)For IGLC3, the sequence is from allele *03 (See Alignment of alleles).
(2)The alleles *02 to *05 of IGLC6 are pseudogenes (stop codon and frameshift due to a 4 nt insertion at position 88).


Created: 02/04/2001
Last updated: Monday, 11-Jul-2011 12:57:02 CEST
Author: Christèle Martinez-Jean
Contact: Marie-Paule Lefranc

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