Protein display: Mouse (Mus musculus, Mus spretus) IGL V-REGIONs

The IGLV protein display numbering is according to the IMGT unique numbering for V-REGION.

Only the *01 allele of each functional, ORF and in-frame pseudogene V-REGION is shown.

Letters in red correspond to amino acids which are polymorphic in the other alleles.
For C-REGIONs, letters in bold correspond to additional positions in the IMGT unique numbering.
For C-REGIONs, letters between parentheses correspond to amino acids resulting from the splicing.

house mouse (Mus musculus) IGLV
____________________________________________________________________________________________________________________________________________________
      IGLV                          FR1-IMGT           CDR1-IMGT       FR2-IMGT      CDR2-IMGT                 FR3-IMGT                  CDR3-IMGT
      gene                           (1-26)             (27-38)        (39-55)        (56-65)                  (66-104)                  (105-115)

__________________________ __________________________ ____________ _________________ __________ _______________________________________ _____________
                           1       10        20         30         40        50         60         70        80        90        100        110
                           .........|.........|...... ...|........ .|.........|..... ....|..... ....|.........|.........|.........|.... .....|......

  J00590  ,IGLV1           QAVVTQESA.LTTSPGETVTLTCRSS TGAVTTSNY... ANWVQEKPDHLFTGLIG GTN....... NRAPGVP.ARFSGSL..IGDKAALTITGAQTEDEAIYFC ALWYSNHF....
  J00599  ,IGLV2           QAVVTQESA.LTTSPGGTVILTCRSS TGAVTTSNY... ANWVQEKPDHLFTGLIG GTS....... NRAPGVP.VRFSGSL..IGDKAALTITGAQTEDDAMYFC ALWYSTHF....
  M34597  ,IGLV3(1)        QLVLTQSSS.ASFSLGASAKLTCTLS SQHSTYT..... IEWYQQQPLKPPKYVME LKKDGSH... STGDGIP.DRFSGSS..SGADRYLSISNIQPEDEAIYIC GVDTIKEQFV*.
° AF357985,IGLV4               TQPSS.VSTSLGSTVKLSCKRS TGNIGNNY.... VHWYQQYMGRSPTNMIY DDN....... KRPSGVS.DRFSGSIDSSSNSAFLTINNVQAED
° AF357981,IGLV5               TQPSS.VSTSLGSTVKLSCKRS TGNIGNNY.... VNWYQQYMGRSPTNMIY GDD....... QRPTGVS.DRFSGSIDSSSNSAFLTINNVQAED
° AF357979,IGLV6               TQPSS.VSTSLGSTVKLPCKCS TGNIGSYY.... VHWYQQHMGRSPTNMIH SDD....... QRPSGVS.DRFSGSIDSSSNSAFLTINNVQAED
° AF357980,IGLV7               TQPSS.VSTSLGSTVKLSCKPS TGKIGNYF.... MSWYQQHMGRSPTNMIY RDD....... LRPSGVS.DRFSGSIDSSSNSAFLTINNVQAED
° AF357982,IGLV8               TQPSS.VSTSLGSTVKLPCKRS TGNIGNDY.... VHWYQQHMGRSPTNMIY RDD....... QRPSGVS.DRFSGSIDSSSNSAFLTINNVQAED

°: genomic DNA, but not known as being germline or rearranged.


Algerian mouse (Mus spretus) IGLV
____________________________________________________________________________________________________________________________________________________
      IGLV                          FR1-IMGT           CDR1-IMGT       FR2-IMGT      CDR2-IMGT                 FR3-IMGT                  CDR3-IMGT
      gene                           (1-26)             (27-38)        (39-55)        (56-65)                  (66-104)                  (105-115)

__________________________ __________________________ ____________ _________________ __________ _______________________________________ _____________
                           1       10        20         30         40        50         60         70        80        90        100        110
                           .........|.........|...... ...|........ .|.........|..... ....|..... ....|.........|.........|.........|.... .....|......

  M17529  ,IGLV2           QAVVTQESA.LTTSPGGTVILTCRSS TGAVTTSNY... AIWVQEKTDHLFAGVIG DTS....... NRAPGVP.ARFSGSL..IGDKAALTITGAQTEDDAMYFC ALWYSNHF.... 
  AF357988,IGLV3           QPVLTQSSS.ASFSLGASAKLTCTLS SEHSTYI..... IEWYQQQPLKPPKYVMQ LKKDGSH... SKGDGIP.DRFSGSS..SGADRYLSISNIQPEDEAIYIC GVDDNIRGQFV.   
° AF357978,IGLV4               TQPSS.VSTSLGSTVKLSCKRS TGNIGNNY.... VHWYQQYMGRSPTNMIY DDN....... KRPSGVS.DRFSGSIDSSSNSAFLTINNVQAED
° AF357977,IGLV8               TQPSS.VSTSLGSTVKLPCKRS TGNIGNNY.... VHWYQQHMGRPPTNMIY RDD....... QRPSGVS.DRFSGSIDSSSNSAFLTINNVQAED

°: genomic DNA, but not known as being germline or rearranged.

(1) The last codon of the CDR3-IMGT is a STOP-CODON which can disappear during rearrangements.


Created: 11/06/1998
Last updated: Thursday, 15-Sep-2011 11:04:03 CEST
Authors: Dominique Scaviner and Delphine Guiraudou
Contact: Marie-Paule Lefranc

Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.


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