The IGLV protein display numbering is according to the IMGT unique numbering for V-REGION.
Only the *01 allele of each functional, ORF and in-frame pseudogene V-REGION is shown.
Letters in red correspond to amino acids which are polymorphic in the other alleles.
For C-REGIONs, letters in bold correspond to additional positions in the IMGT unique numbering.
For C-REGIONs, letters between parentheses correspond to amino acids resulting from the splicing.
____________________________________________________________________________________________________________________________________________________
IGLV FR1-IMGT CDR1-IMGT FR2-IMGT CDR2-IMGT FR3-IMGT CDR3-IMGT
gene (1-26) (27-38) (39-55) (56-65) (66-104) (105-115)
__________________________ __________________________ ____________ _________________ __________ _______________________________________ _____________
1 10 20 30 40 50 60 70 80 90 100 110
.........|.........|...... ...|........ .|.........|..... ....|..... ....|.........|.........|.........|.... .....|......
J00590 ,IGLV1 QAVVTQESA.LTTSPGETVTLTCRSS TGAVTTSNY... ANWVQEKPDHLFTGLIG GTN....... NRAPGVP.ARFSGSL..IGDKAALTITGAQTEDEAIYFC ALWYSNHF....
J00599 ,IGLV2 QAVVTQESA.LTTSPGGTVILTCRSS TGAVTTSNY... ANWVQEKPDHLFTGLIG GTS....... NRAPGVP.VRFSGSL..IGDKAALTITGAQTEDDAMYFC ALWYSTHF....
M34597 ,IGLV3(1) QLVLTQSSS.ASFSLGASAKLTCTLS SQHSTYT..... IEWYQQQPLKPPKYVME LKKDGSH... STGDGIP.DRFSGSS..SGADRYLSISNIQPEDEAIYIC GVDTIKEQFV*.
° AF357985,IGLV4 TQPSS.VSTSLGSTVKLSCKRS TGNIGNNY.... VHWYQQYMGRSPTNMIY DDN....... KRPSGVS.DRFSGSIDSSSNSAFLTINNVQAED
° AF357981,IGLV5 TQPSS.VSTSLGSTVKLSCKRS TGNIGNNY.... VNWYQQYMGRSPTNMIY GDD....... QRPTGVS.DRFSGSIDSSSNSAFLTINNVQAED
° AF357979,IGLV6 TQPSS.VSTSLGSTVKLPCKCS TGNIGSYY.... VHWYQQHMGRSPTNMIH SDD....... QRPSGVS.DRFSGSIDSSSNSAFLTINNVQAED
° AF357980,IGLV7 TQPSS.VSTSLGSTVKLSCKPS TGKIGNYF.... MSWYQQHMGRSPTNMIY RDD....... LRPSGVS.DRFSGSIDSSSNSAFLTINNVQAED
° AF357982,IGLV8 TQPSS.VSTSLGSTVKLPCKRS TGNIGNDY.... VHWYQQHMGRSPTNMIY RDD....... QRPSGVS.DRFSGSIDSSSNSAFLTINNVQAED
°: genomic DNA, but not known as being germline or rearranged.
____________________________________________________________________________________________________________________________________________________
IGLV FR1-IMGT CDR1-IMGT FR2-IMGT CDR2-IMGT FR3-IMGT CDR3-IMGT
gene (1-26) (27-38) (39-55) (56-65) (66-104) (105-115)
__________________________ __________________________ ____________ _________________ __________ _______________________________________ _____________
1 10 20 30 40 50 60 70 80 90 100 110
.........|.........|...... ...|........ .|.........|..... ....|..... ....|.........|.........|.........|.... .....|......
M17529 ,IGLV2 QAVVTQESA.LTTSPGGTVILTCRSS TGAVTTSNY... AIWVQEKTDHLFAGVIG DTS....... NRAPGVP.ARFSGSL..IGDKAALTITGAQTEDDAMYFC ALWYSNHF....
AF357988,IGLV3 QPVLTQSSS.ASFSLGASAKLTCTLS SEHSTYI..... IEWYQQQPLKPPKYVMQ LKKDGSH... SKGDGIP.DRFSGSS..SGADRYLSISNIQPEDEAIYIC GVDDNIRGQFV.
° AF357978,IGLV4 TQPSS.VSTSLGSTVKLSCKRS TGNIGNNY.... VHWYQQYMGRSPTNMIY DDN....... KRPSGVS.DRFSGSIDSSSNSAFLTINNVQAED
° AF357977,IGLV8 TQPSS.VSTSLGSTVKLPCKRS TGNIGNNY.... VHWYQQHMGRPPTNMIY RDD....... QRPSGVS.DRFSGSIDSSSNSAFLTINNVQAED
°: genomic DNA, but not known as being germline or rearranged.
(1) The last codon of the CDR3-IMGT is a STOP-CODON which
can disappear during rearrangements.
Created: 11/06/1998
Last updated: Monday, 17-Mar-2008 11:22:27 CET
Authors: Dominique Scaviner and Delphine Guiraudou
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.
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