Only functional TRBV genes and alleles are listed.The reactivities of the reagents monoclonal antibodies for different variable regions are shown between parentheses in the 'Clone name and Specificity' column.
This table lists reagents monoclonal antibodies, specific for the T cell Receptor Beta Variable regions (TRBV), which are commercially available.
Companies are encouraged to inform us of commercially available antibodies.
Only functional TRBV genes and alleles are listed.
The reactivities of the reagents monoclonal antibodies for different variable regions are shown between parentheses in the 'Clone name and Specificity' column.
% of peripheral CD3 positive cells in normal blood are from the Coulter, Serotec or BD Biosciences Web sites.
The reactivities as described in this table are not exhaustive. For more information on the products and their reactivity, please contact the companies:
Pierce Endogen,
Serotec,
Coulter and
BD Biosciences.
| TRBV gene name |
TRBV allele name |
Reagents monoclonal antibodies | |||
| Clone name and Specificity | Company product | Isotype | % of peripheral CD3 positive cells in normal blood |
||
| TRBV2 | TRBV2*01 | IMMU 546 (TRBV2) | Serotec V BETA 22 Coulter Vbeta22 |
Mouse IgG1 | 2.4-5.1 |
| TRBV2*02 | |||||
| TRBV2*03 | |||||
| TRBV3-1 | TRBV3-1*01 | FIN9 (TRBV3-1) AMKB1-2 (TRBV3-1) |
Serotec Vbeta9 Coulter Vbeta9 |
Mouse IgG2a Mouse IgG1 |
1.6-3.2 0.5-3 |
| TRBV3-1*02 | BD Biosciences Vbeta9 | ||||
| TRBV4-1 | TRBV4-1*01 | ZOE (TRBV4-1, TRBV4-2, TRBV4-3) 3G5 (TRBV4-1) |
Serotec V BETA 7 Coulter Vbeta7 |
Mouse IgG2a | 1.5-2.4 |
| TRBV4-1*02 | Pierce EndogenV beta 7.1 | Mouse IgG2b |
|||
| TRBV4-2 | TRBV4-2*01 | ZOE (TRBV4-1, TRBV4-2, TRBV4-3) | Serotec V BETA 7 Coulter Vbeta7 |
Mouse IgG2a | |
| TRBV4-2*02 | |||||
| TRBV4-3 | TRBV4-3*01 | ZOE (TRBV4-1, TRBV4-2, TRBV4-3) | Serotec V BETA 7 Coulter Vbeta7 |
Mouse IgG2a | |
| TRBV4-3*02 | |||||
| TRBV4-3*03 | |||||
| TRBV4-3*04 | |||||
| TRBV5-1 | TRBV5-1*01 | IMMU157 (TRBV5-1)
|
Serotec Vbeta5.1 Coulter Vbeta5.1 |
Mouse IgG2a | 4.8 4.2-7.2 0.5-3 |
| TRBV5-1*02 | Pierce Endogen V beta 5(c) BD Biosciences Vbeta5(c) |
Mouse IgG1 | |||
| TRBV5-4 | TRBV5-4*01 | ||||
| TRBV5-4*02 | |||||
| TRBV5-4*03 | |||||
| TRBV5-4*04 | |||||
| TRBV5-5 | TRBV5-5*01 | 3D11 (TRBV5-5)
|
Serotec VBETA5.3< Coulter Vbeta5.3 |
Mouse IgG1 | 1-1.8 (mean 1.4) 0.5-3 0.5-3 0.5-3 |
| TRBV5-5*02 | Pierce Endogen V beta 5(a) BD Biosciences Vbeta5(a) |
Mouse IgG1 | |||
| TRBV5-5*03 | Pierce Endogen V beta 5(b) Serotec V beta 5.2/5.3 BD Biosciences Vbeta5(b) |
Mouse IgG1 | |||
| BD Biosciences Vbeta5 | Mouse IgG2a | ||||
| TRBV5-6 | TRBV5-6*01 | 36213 (TRBV5-6) 1C1 (TRBV5-5, TRBV5-6)
|
Serotec Vbeta5.2 |
Mouse IgG1 Mouse IgG1 Mouse IgG2a |
0.5-1.5 0.5-1.5 (mean 0.8) 0.5-3 0.5-3 |
| BD Biosciences Vbeta5(a) | |||||
| BD Biosciences Vbeta5 | |||||
| TRBV5-8 | TRBV5-8*01 | ||||
| TRBV5-8*02 | |||||
| TRBV6-1 | TRBV6-1*01 | BAM13 (TRBV6-1, TRBV6-5) | Pierce Endogen V beta 13 BD Biosciences Vbeta13.1, 13.3 |
Mouse IgG1 | 3-6 |
| TRBV6-2 | TRBV6-2*01 | ||||
| TRBV6-3 | TRBV6-3*01 | ||||
| TRBV6-4 | TRBV6-4*01 | ||||
| TRBV6-4*02 | |||||
| TRBV6-5 | TRBV6-5*01 | IMMU 222 (TRBV6-5, TRBV6-6 and TRBV6-9)
|
Serotec V BETA 13.1 Coulter Vbeta13.1 |
Mouse IgG2b | 1.8-3.3 (JU74.3: 0.9-1.9) 3-6 |
| Pierce Endogen V beta 13 BD Biosciences Vbeta13.1, 13.3 |
Mouse IgG1 | ||||
| TRBV6-6 | TRBV6-6*01 | JU-74 (TRBV6-6) JU74.3 (TRBV6-6)
|
Serotec Vbeta13.6 Coulter Vbeta13.6 |
Mouse IgG1 | |
| TRBV6-6*02 | |||||
| TRBV6-6*03 | |||||
| TRBV6-6*04 | Serotec V BETA 13.1 Coulter Vbeta13.1 |
Mouse IgG2b | |||
| TRBV6-6*05 | |||||
| TRBV6-8 | TRBV6-8*01 | ||||
| TRBV6-9 | TRBV6-9*01 | IMMU 222 (TRBV6-5, TRBV6-6 and TRBV6-9) | Serotec V BETA 13.1 Coulter Vbeta13.1 |
Mouse IgG2b | |
| TRBV7-2 | TRBV7-2*01 | OT145 (TRBV7-2) | Pierce Endogen V beta 6.7 BD Biosciences Vbeta6.7 |
Mouse IgG1 |
|
| TRBV7-2*02 | |||||
| TRBV7-2*03 | |||||
| TRBV7-2*04 | |||||
| TRBV7-3 | TRBV7-3*01 | ||||
| TRBV7-3*04 | |||||
| TRBV7-3*05 | |||||
| TRBV7-4 | TRBV7-4*01 | ||||
| TRBV7-6 | TRBV7-6*01 | ||||
| TRBV7-6*02 | |||||
| TRBV7-7 | TRBV7-7*01 | ||||
| TRBV7-7*02 | |||||
| TRBV7-8 | TRBV7-8*01 | ||||
| TRBV7-8*02 | |||||
| TRBV7-8*03 | |||||
| TRBV7-9 | TRBV7-9*01 | ||||
| TRBV7-9*02 | |||||
| TRBV7-9*03 | |||||
| TRVB7-9*04 | |||||
| TRBV7-9*05 | |||||
| TRBV7-9*06 | |||||
| TRBV7-9*07 | |||||
| TRBV9 | TRBV9*01 | BL37.2 (TRBV9) | Serotec Vbeta1 Coulter Vbeta1 |
Rat IgG1 | 2.4 - 6.6 6 |
| TRBV9*02 | |||||
| TRBV9*03 | |||||
| TRBV10-1 | TRBV10-1*01 | S511 (TRBV10-1, TRBV10-2, TRBV10-3) | Pierce Endogen V beta 12 BD Biosciences Vbeta12 |
Mouse IgG2b | 0.5-3 |
| TRBV10-1*02 | |||||
| TRBV10-2 | TRBV10-2*01 | ||||
| TRBV10-2*02 | |||||
| TRBV10-3 | TRBV10-3*01 | VER2.32.1 (TRBV10-3)
|
Serotec Vbeta12 Coulter Vbeta12 |
Mouse IgG2a | 1.5 1.1-1.9 0.5-3 |
| TRBV10-3*02 | |||||
| TRBV10-3*03 | Pierce Endogen V beta 12 BD Biosciences Vbeta12 |
Mouse IgG2b | |||
| TRBV10-3*04 | |||||
| TRBV11-1 | TRBV11-1*01 | ||||
| TRBV11-2 | TRBV11-2*01 | IG125 (TRBV11-2) | Serotec Vbeta21.3 Coulter Vbeta21.3 |
Mouse IgG2a | 2.2-3.6 |
| TRBV11-2*02 | |||||
| TRBV11-2*03 | |||||
| TRBV11-3 | TRBV11-3*01 | ||||
| TRBV11-3*02 | |||||
| TRBV11-3*03 | |||||
| TRBV11-3*04 | |||||
| TRBV12-3 | TRBV12-3*01 | 56C5 (TRBV12-3, TRBV12-4) 56C5.2 (TRBV12-3, TRBV12-4)
MX-6 (TRBV12-3, TRBV12-4) JR2 (TRBV12-3, TRBV12-4, TRBV12-5) |
Serotec Vbeta8.1/8.2 Coulter Vbeta8 |
Mouse IgG2a | 4.2 2.6-5.1
|
| TRBV12-4 | TRBV12-4*01 | Pierce Endogen V beta 8(a) BD Biosciences Vbeta8 |
Mouse IgG2b | ||
| TRBV12-4*02 | Pierce Endogen V beta 8(b) | Mouse IgG2a | |||
| BD Biosciences Vbeta8 | Mouse IgG2b | ||||
| TRBV12-5 | TRBV12-5*01 | JR2 (TRBV12-3, TRBV12-4, TRBV12-5) | BD Biosciences Vbeta8 | Mouse IgG2b | 0.5-3 |
| TRBV13 | TRBV13*01 | AF-23 (TRBV13) AF23 (TRBV13) AHUT7 (Vbeta23) |
Serotec Vbeta23 Coulter Vbeta23 BD Biosciences Vbeta23 |
Mouse IgG1 | 0.4-5 0.5-3 |
| TRBV13*02 | |||||
| TRBV14 | TRBV14*01 | TAMAYA1.2 (TRBV14) | Serotec Vbeta16 Coulter Vbeta16 |
Mouse IgG1 | 0.8 0.4-1.1 |
| TRBV14*02 | |||||
| TRBV15 | TRBV15*01 | ||||
| TRBV15*02 | |||||
| TRBV15*03 | |||||
| TRBV16 | TRBV16*01 | ||||
| TRBV16*03 | |||||
| TRBV18 | TRBV18*01 | BA62 (TRBV18) BA62.6 (TRBV18) |
Serotec V BETA 18 Coulter Vbeta18 |
Mouse IgG1 | 0.7-2.2 0.7-1.4 |
| TRBV19 | TRBV19*01 | C1 (TRBV19) E17.5F3 (TRBV19) |
Pierce Endogen V beta 17 BD Biosciences Vbeta17 |
Mouse IgG1 | 0.5-3 |
| TRBV19*02 | Serotec Vbeta17 Coulter Vbeta17 |
Mouse IgG1 | |||
| TRBV19*03 | |||||
| TRBV20-1 | TRBV20-1*01 | MPB2D5 (TRBV20-1) | Serotec VBETA2 Coulter Vbeta2 |
Mouse IgG1 | 4.2-9.1 10 |
| TRBV20-1*02 | |||||
| TRBV20-1*03 | |||||
| TRBV20-1*04 | |||||
| TRBV20-1*05 | |||||
| TRBV20-1*06 | |||||
| TRBV20-1*07 | |||||
| TRBV24-1 | TRBV24-1*01 | ||||
| TRBV25-1 | TRBV25-1*01 | C21 (TRBV25-1) | Serotec V BETA 11 Coulter Vbeta11 |
Mouse IgG2a | 0.8 0.4-0.9 |
| TRBV27 | TRBV27*01 | CAS1.1.3 (TRBV27) | Serotec Vbeta14 Coulter Vbeta14 |
Mouse IgG1 | 2.2-5.6 |
| TRBV28 | TRBV28*01 | CH92 (TRBV28)
JOVI-3 (TRBV28) |
Serotec Vbeta3 Coulter Vbeta3 |
Mouse IgM | 2.9 2.2-5.6 3 |
| Pierce Endogen V beta 3.1 BD Biosciences Vbeta3 |
Mouse IgG1 Mouse IgG2a |
||||
| TRBV29-1 | TRBV29-1*01 | ||||
| TRBV29-1*02 | |||||
| TRBV29-1*03 | |||||
| TRBV30 | TRBV30*01 | ELL1.4 (TRBV30) | Serotec Vbeta20 Coulter Vbeta20 |
Mouse IgG1 | 2.2 |
| TRBV30*02 | |||||
| TRBV30*04 | |||||
| TRBV30*05 | |||||
Created: 24/06/2003
Author: Géraldine Folch
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
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IMGT founder and director: Marie-Paule Lefranc
Marie-Paule.Lefranc@igh.cnrs.fr
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