In this table are listed the rearranged complementary DNAs (cDNAs) and genomic DNAs (gDNAs) which are quoted in Arden, B. et al., Immunogenetics, 42, 455-500 (1995), which represent potential new alleles without known germline sequences, or which have interesting characteristics.
Rearranged cDNAs (#c) and gDNAs (#g) TRDV sequences have been assigned to IMGT TRDV genes and alleles as described in Germline gene tables, Alignments of alleles and Tables of alleles. Assignments were performed using IMGT/V-QUEST.
References are presented chronologically whenever possible.
| TRDV
gene name |
Reference sequences | Rearranged cDNAs and gDNAs | CDR lengths | JUNCTION (1) | ||
| Allele name | Accession number |
Clone name | Accession numbers | |||
| 1 | TRDV1*01 | M22198 | KT10E | X14545 [5]#c | [7.3.15] | + |
| M18414 [1]#c | [7.3.24] | + | ||||
| D105 | X15021 [3]#c | [7.3.14] | + | |||
| Pr81 | X06557/Y00289 [2]#c | [7.3.16] | + | |||
| CTL55 | AB164056 [9](2)#c | [7.3.11] | + | |||
| 2 | TRDV2*01 | X15207 | LB117 | X13950 [6]#c | [8.3.13] | + |
| LB207 | X13952 [6]#c | [8.3.16] | + | |||
| LB210 | X13951 [6]#c | [8.3.18] | + | |||
| KT19E | X14546 [5]#c | [8.3.20] | + | |||
| TRDV2*03 | AE000661 | X53849 [4]#c | [8.3.16] | + | ||
| M21784 [7]#c | [8.3.16] | + | ||||
| KT14E | X14547 [5]#c | [8.3.17] | + | |||
| X72501 [8]#c | [8.3.16] | + | ||||
| 3 | TRDV3*01 | M23326 | KT041 | X14544 [5]#c | [7.5.21] | + |
| (1) | + indicates in-frame JUNCTION, - indicates out-of-frame JUNCTION, a blank indicates not defined. |
| (2) |
TRDV1*01 rearranged to TRAJ54*01. Another example of the TRDV1 gene being rearranged to a TRAJ gene was described in
[10]. Comments added by M.-P. Lefranc on the 08/03/2003, based on information kindly provided by T. Ueno (Japan) on the 25/10/2002 and the CTL55 sequence submission to DDBJ on the 04/03/2003. |
References:
| [1] | Hata, S. et al., Science, 238, 678-682 (1987). |
| [2] | Loh, E.Y. et al., Nature, 330, 569-572 (1987). |
| [3] | Okada, A. et al., J. Exp. Med., 168, 1481-1486 (1988). |
| [4] | Triebel, F. et al., J. Immunol., 140, 300-304 (1988). |
| [5] | Takihara, Y. et al., J. Exp. Med., 169, 393-405 (1989). |
| [6] | Hata, S. et al., J. Exp. Med., 169, 41-57 (1989). |
| [7] | Loh, E.Y. et al., Science, 243, 217-220 (1989). |
| [8] | Davodeau, F., et al., J. Biol. Chem., 268, 15455-15460 (1993). |
| [9] | Ueno, T. et al., Eur. J. Immunol., 33, 2910-2916 (2003) PMID:14515275 |
| [10] | Miossec, C. et al., J. Exp. Med., 171, 1171-1188 (1990) PMID:2182762 |
Created: 17/01/2001
Last updated: Wednesday, 29-Jun-2011 17:06:09 CEST
Authors: Géraldine Folch and Marie-Paule Lefranc
Contact: Marie-Paule Lefranc
Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
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