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Information on IMGT®

• IMGT autority: LIGM (Montpellier)
• IMGT references
• IMGT information system overview
• IMGT server environment
• IMGT history
• IMGT executive and scientific committees
• IMGT creations and updates
• IMGT Livre d'Or
• Frequently asked questions (FAQ)
• Citing IMGT
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IMGT Databases

• IMGT Sequence databases
  • IMGT/LIGM-DB
  • IMGT/MHC-DB (hosted at EBI)
  • IMGT/PRIMER-DB
  • IMGT/CLL-DB
• IMGT Genome database
  • IMGT/GENE-DB
• IMGT Structure database
  • IMGT/3Dstructure-DB and IMGT/2Dstructure-DB
• IMGT monoclonal antibodies database
  • IMGT/mAb-DB

IMGT tools

• IMGT Sequence tools
  • IMGT/V-QUEST
  • IMGT/JunctionAnalysis
  • IMGT/HighV-QUEST
  • IMGT/Allele-Align
  • IMGT/PhyloGene
  • IMGT/DomainDisplay
• IMGT Genome tools
  • IMGT/LocusView, IMGT/GeneView, IMGT/GeneSearch, IMGT/CloneSearch
  • IMGT/GeneInfo
  • IMGT/GeneFrequency
• IMGT 3D structure tools
  • IMGT/DomainGapAlign
  • IMGT/Collier-de-Perles
  • IMGT/DomainSuperimpose
  • IMGT/StructuralQuery

IMGT Web resources

• IMGT Repertoire (IG and TR)
  1. Locus and genes
     • Chromosomal localizations
     • Locus representations
     • Locus description
     • Gene positions
     • Gene exon/intron organization
     • Gene exon/intron splicing sites
     • Gene tables
     • Potential germline repertoires
     • Lists of human IG and TR genes, groups, loci and orphons
     • Lists of Mouse (Mus musculus) IG and TR genes, groups, loci and orphons
     • Clans
     • Correspondence between nomenclatures
     • Correspondence between species
  2. Proteins and alleles
     • Protein displays
     • Alignments of alleles
     • Tables of alleles
     • Allotypes
     • Isotypes
     • Particularities in protein designations
     • IMGT reference directory in FASTA format
     • Correspondence between IG and TR chain, gene and receptor IMGT designations
  3. 2D and 3D structures
     • Colliers de Perles
       • V-REGION
       • V-DOMAIN (V-J-REGION and V-D-J-REGION)
       • C-DOMAIN
     • Colliers de Perles with hydrogen bonds
     • 3D representations
       • V-DOMAIN
       • C-DOMAIN
     • FR-IMGT and CDR-IMGT lengths (V-REGION and V-DOMAIN)
       • FR-IMGT and CDR-IMGT (V-REGION)
       • CDR1-IMGT (summary) and correspondence with "canonical structures"
       • CDR2-IMGT (summary) and correspondence with "canonical structures"
       • CDR3-IMGT (V-DOMAIN)
     • CDR-IMGT 3D structures
       • CDR1-IMGT
       • CDR2-IMGT
     • Strand and loop lengths (C-DOMAIN)
     • Examples of C-DOMAINs
       • Protein displays
       • Strand and loop lengths
     • Proteins with known 3D structures
       • Overview
       • Identification and Colliers de Perles
       • Protein display V-DOMAIN
       • Classification by gene names
       • Classification by CDR-IMGT lengths
  4. Probes and RFLP
     • Phages
     • Probes
     • RFLP alleles and frequencies
     • Polymorphisms by insertion/deletion
     • Rearrangements
  5. Taxonomy
     • IMGT taxonomy tree
     • List of the species in IMGT
     • List of the mouse strains in IMGT Repertoire
     • Non-vertebrates in IMGT/LIGM-DB
  6. Gene regulation and expression
     • Promoters
       • Motifs
       • Organization
     • cDNAs
     • Reagents monoclonal antibodies
  7. Genes and clinical entities
     • Translocations and inversions
     • Humanized antibodies
       • Alemtuzumab (Campath-1H)
       • K20
       • Bevacizumab and ranibizumab
     • Monoclonal antibodies with clinical indications

• IMGT Repertoire (MH)
  1. Locus and genes
     • Chromosomal localizations
     • Locus representation
     • IMGT/LocusView complete locus
     • IMGT/GeneSearch list of genes
     • IMGT/GeneView query
     • Gene exon/intron organization
     • Lists of MHC genes and loci
     • MHC-I gene examples in vertebrates
     • Representative MHC genes and chains
     • Correspondence between nomenclatures
  2. Proteins and alleles
     • Protein displays G-DOMAINs
       • G-ALPHA1 and G-ALPHA2
       • G-ALPHA
       • G-BETA
     • Protein displays C-LIKE-DOMAIN
  3. 2D and 3D structures
     • Colliers de Perles
       • G-DOMAINs
       • C-LIKE-DOMAINs
     • 3D representation
       • C-LIKE-DOMAINs
     • Strand and loop lengths
       • MHC-I
       • MHC-II
  4. Polymorphism
     • Serological families and alleles: Human MHC: HLA-A
     • Haplotypes HLA-DRB
     • Polymorphisms in the introns: MHC-I-Alpha HLA-A
     • Mouse H2 haplotypes and polymorphisms
     • Consomic vs. congenic strains (mouse and rat)
  5. Taxonomy
     • IMGT Taxonomy tree

• IMGT Repertoire (RPI)
  1. Locus and genes
     • Gene tables
     • Correspondence between nomenclatures
     • Gene exon/intron organization
     • Representative MHC-I-like genes and chains
  2. Proteins and alleles
     • Protein displays
       • V-LIKE-DOMAINs
       • C-LIKE-DOMAINs
       • G-LIKE-ALPHA1-DOMAINs [D1]
       • G-LIKE-ALPHA2-DOMAINs [D2]
     • Alignments of alleles
       • V-LIKE-DOMAINs
       • C-LIKE-DOMAINs
     • Tables of alleles
       • V-LIKE-DOMAINs
       • C-LIKE-DOMAINs
  3. 2D and 3D structures
     • Colliers de Perles
       • V-LIKE-DOMAINs
       • C-LIKE-DOMAINs
       • G-LIKE-DOMAINs
     • 3D representation
       • V-LIKE-DOMAINs
       • C-LIKE-DOMAINs
     • Strand and loop lengths
       • C-LIKE-DOMAINs
       • G-LIKE-ALPHA1-DOMAINs
       • G-LIKE-ALPHA2-DOMAINs
  4. RPI entries from gene to protein
     • IgSF other than IG or TR
     • MhcSF other than MHC

• IMGT Index

• IMGT Scientific chart
  1. Sequence and 3D structure identification and description
     • IMGT reference sequences
     • IMGT standardized keywords
     • IMGT/LIGM-DB standardized labels
     • V-GENE prototypes with IMGT/LIGM-DB labels
     • Functionality
     • How to qualify a gene (structure and localization)
     • IMGT/PROTEIN-DB and IMGT/3Dstructure-DB: Standardized keywords and labels for IG, TR and MHC
     • IMGT/PROTEIN-DB and IMGT/3Dstructure-DB: Label definitions for IG, TR and MHC
     • Correspondence between labels for IG and TR domains in IMGT/3Dstructure-DB and IMGT/LIGM-DB
     • Lengths of the G-DOMAIN and G-LIKE-DOMAIN labels
  2. Numbering
     • IMGT numbering for coding regions (Overview)
     • IMGT numbering of additional codons (or amino acids) and corresponding nucleotides
     • IMGT unique numbering for V-REGION
     • IMGT unique numbering for V-DOMAIN and V-LIKE-DOMAIN
     • IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN
     • IMGT unique numbering for G-DOMAIN and G-LIKE-DOMAIN
     • Rules for the gaps and additional positions in C-DOMAIN and C-LIKE-DOMAIN
     • Correspondence between V numberings
     • Correspondence between C numberings
     • Correspondence between G numberings
  3. Nomenclature
     • IMGT gene name nomenclature for IG and TR of human and other vertebrates
     • Definition of the FR-IMGT and CDR-IMGT regions
     • IMGT allele nomenclature for sequence polymorphisms
     • IMGT taxon abbreviations
     • IMGT description of mutations
     • IMGT RFLP allele nomenclature
     • Correspondence between the different nomenclatures
  4. Representation rules
     • IMGT color menu
     • Abbreviations
     • Uncertain nucleotides
     • IMGT orthographe
     • IMGT annotation rules

• IMGT Bloc-notes

• IMGT Education
  • IMGT Lexique
  • Aide-mémoire
  • Tutorials
  • Questions and answers
  • Enseignements de Marie-Paule Lefranc

• IMGT Posters and diaporama

IMGT other accesses

• IMGT Other accesses
  • IMGT/LIGM-DB
    • SRS
    • MRS
  • IMGT/HLA-DB
• Compare your sequence against IMGT
  • IMGT/LIGM-DB
    • BLAST
    • FASTA
  • IMGT/HLA-DB
• IMGT/LIGM-DB Sequence submission
• IMGT downloads
• Search IMGT domain (Google)

Created: 05/12/2002
Last updated: Tuesday, 24-Jan-2012 22:01:41 CET
Author: Chantal Ginestoux
Contact: Marie-Paule Lefranc

IMGT Home page | IMGT Repertoire (IG and TR) | IMGT Repertoire (MH) | IMGT Repertoire (RPI) | IMGT Index | IMGT Scientific chart | IMGT Education

Software material and data coming from IMGT server may be used for academic research only, provided that it is referred to IMGT®, and cited as "IMGT®, the international ImMunoGeneTics information system® http://www.imgt.org (founder and director: Marie-Paule Lefranc, Montpellier, France)." References to cite: Lefranc, M.-P. et al., Nucleic Acids Research, 27, 209-212 (1999) Cover of NAR; Ruiz, M. et al., Nucleic Acids Research, 28, 219-221 (2000); Lefranc, M.-P., Nucleic Acids Research, 29, 207-209 (2001); Lefranc, M.-P., Nucleic Acids Res., 31, 307-310 (2003); Lefranc, M.-P. et al., In Silico Biol., 5, 0006 (2004) [Epub], 5, 45-60 (2005); Lefranc, M.-P. et al., Nucleic Acids Res., 33, D593-D597 (2005) Full text; Lefranc, M.-P. et al., Nucleic Acids Research 2009 37: D1006-D1012; doi:10.1093/nar/gkn838 Full text.
For any other use please contact Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr.

     

IMGT founder and director: Marie-Paule Lefranc Marie-Paule.Lefranc@igh.cnrs.fr
Bioinformatics manager: Véronique Giudicelli Veronique.Giudicelli@igh.cnrs.fr
Computer manager: Patrice Duroux Patrice.Duroux@igh.cnrs.fr
Webmaster: Chantal Ginestoux Chantal.Ginestoux@igh.cnrs.fr

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