Citing IMGT dynamic tools: Sanou G., Zeitoun G. et al. IMGT® at scale: FAIR, Dynamic and Automated Tools for Immune Locus Analysis, Nucleic Acids Research. 2025;,gkaf1024. doi: 10.1093/nar/gkaf1024 (Free Article) PMID: 41091930.
Program version: v. 

Add information about removed genes/alleles.
May 15th, 2025.

Add the possibility to obtain a gene table per strain (for mouse now and for other species later) and allotypes/isotypes for human.
September 25th, 2024.

Bibliographical references in alphabetic order, small design changes and addition of "NL" for non-localized gene.
June 14th, 2024.

Addition of 'Score for IMGT allele confirmation' as well as NCBI TPA accession numbers.
September 20th, 2023.

Implementation of the dynamic gene table.

Gene table legend:

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene, when the data have been confirmed by several studies.

Functionality is shown in parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.

IMGT allele confirmation: A scoring system is employed to indicate the number of IMGT/LIGM-DB reference sequences and other sequences from the literature in which an IG or TR gene allele has been identified and annotated.

Removed genes/alleles
If a gene/allele existence or name has to be changed, the old name or gene/allele would be deleted and its name won't be reused. They are kept in the gene table for historical reasons.
A single star ()
indicates that an IG or TR gene allele is annotated in the reference sequence only.
Two stars ()
indicate that an IG or TR gene allele is annotated in its reference sequence and in one sequence from the literature.
Three stars ()
indicate that an IG or TR gene allele is annotated in its reference sequence and in at least two sequences from the literature.
In the Excel file, the stars are represented by the plus symbol (+).

Click on:
  • IMGT gene name to get the corresponding IMGT/GENE-DB entry (link).
  • IMGT allele name to see the corresponding Alignments of alleles (link).
  • Accession number to get the corresponding IMGT/LIGM-DB entry (link).
  • MAP: mapped sequences. Click to access GENE-DB «LOCALIZATION IN GENOME ASSEMBLIES» (link).
  • [number] to access the corresponding IMGT reference (popover).
  • (number) to see the corresponding IMGT note (popover).
Options:
  • You can show/hide columns (), download data () or put the table in fullscreen () using buttons.
See also (IMGT Scientific chart):
Select a species and a IMGT group to get the gene table:
Only IMGT available species/group are shown in the drop-down list.
The gene table can take several seconds to appear, please be patient.

Click here to see Human IGLJ-C/OR18 processed gene

Gene table of human (Homo sapiens) IGLJ IMGT group:
IMGT gene nameIMGT allele nameScore for
IMGT allele
confirmation		FctChromosomosal
localization		R T PrIMGT/LIGM-DB reference sequencesIMGT/LIGM-DB sequences from the literature
Clone namesAccession
numbers		Positions
in the sequence
(J-GENE-UNIT)
or J-REGION (*)		Secondary
accession
numbers		Clone namesAccession
numbers		Positions
in the sequence
(J-GENE-UNIT)
or J-REGION (*)
IGLJ1 IGLJ1*01 F 22q11.2
RTPr
++
 J1 X04457 [2] MAP (1) 30-67 * D87023 [10] (1) 19380-19417 *
IMGT000225 [5,11] ° 877678-877743
IMGT000280 [12] ° 893695-893760
IMGT000293 [3,8] 890307-890372
X06877 [15] (1) 29-66 *
X51755 [16] (1) 2428-2465 *
IGLJ2 IGLJ2*01 F 22q11.2
RTPr
++
 J2 M15641 [14] MAP 29-66 * D87023 [10] 25217-25254 *
IMGT000225 [5,11] ° 883515-883580
IMGT000280 [12] ° 899532-899597
IMGT000293 [3,8] 896147-896212
X06878 [15] 72-109 *
X51755 [16] 8249-8286 *
IGLJ2A IGLJ2A*01 F 22q11.2 IMGT000293 [3,8] 901512-901577
IGLJ3 IGLJ3*01 F 22q11.2
RTPr
++
 J3 M15642 [14] 29-66 * IMGT000293 [3,8] 906876-906942
X51755 [16] 13639-13676 *
IGLJ3 IGLJ3*02 F 22q11.2
RTPr
++
 3 D87023 [10] MAP 30587-30624 * IMGT000225 [5,11] ° 888885-888950
IMGT000280 [12] ° 904902-904967
IGLJ4 IGLJ4*01 ORF (2) 22q11.2
RTPr
++
 J4 X51755 [16] MAP 19209-19246 * D87017 [10] 7683-7720 *
D87023 [10] 36159-36196 *
IMGT000225 [5,11] ° 894467-894532
IMGT000280 [12] ° 910484-910549
IMGT000293 [3,8] 912459-912524
IGLJ5 IGLJ5*01 ORF (2) 22q11.2
RTPr
++
 J5 X51755 [16] MAP 22918-22955 * IMGT000225 [5,11] ° 898169-898234
IMGT000280 [12] ° 914187-914252
IMGT000293 [3,8] 916162-916227
X57808 [6] 437-474 *
IGLJ5 IGLJ5*02 ORF (2) 22q11.2
RTPr
++
 J5 D87017 [10] 11386-11423 *
IGLJ6 IGLJ6*01 F 22q11.2
RTPr
++
 J6 M18338 [7,9] MAP 30-67 * X58181 [13] D87017 [10] 15279-15316 *
IMGT000225 [5,11] ° 902061-902126
IMGT000280 [12] ° 918079-918144
IMGT000293 [3,8] 920055-920120
M61768 [1] 29-66 *
X51755 [16] (3) 26799-26832 *
X57808 [6] 4330-4367 *
IGLJ7 IGLJ7*01 F 22q11.2
RTPr
++
 J7 X51755 [16] MAP 30017-30054 * IMGT000225 [5,11] ° 905295-905360
IMGT000280 [12] ° 921313-921378
IMGT000293 [3,8] 923289-923354
M61770 [1] 29-66 *
X57808 [6] 7549-7586 *
IGLJ7 IGLJ7*02 F 22q11.2
RTPr
++
 J7 D87017 [10] 18513-18550 *
IMGT notes: ↑
  1. The IGLJ1*01 gene and allele (including its J-RS) is part of the EX2 of the IGLL5*01 gene and allele (IGLL5 is a RPI gene that comprises three exons as identified in the X51755 and D87023 genomic sequences) (Gene and allele table: Human (Homo sapiens) IGLL)
  2. Non-canonical DONOR-SPLICE (nat instead of ngt).
  3. The IGLJ6 sequence from X51755 is not shown in the alignment of alleles since its sequence contains four typing errors (four deletions of 1 nucleotide: t7, g14, c18, g25, according to IMGT numbering for coding regions (Overview)).
IMGT references: ↑
  1. Bauer T.R.Jr. and Blomberg B, The human lambda L chain Ig locus. Recharacterization of JC lambda 6 and identification of a functional JC lambda 7, J. Immunol, vol. 146, no. 8, 1991, pp. 2813-2820. PUBMED: 1901886
  2. Chang H. et al., Identification of three new Ig lambda-like genes in man, J. Exp. Med, vol. 163, no. 2, 1986, pp. 425-435. DOI: 10.1084/jem.163.2.425
  3. Chu et al., Approaching an Error-Free Diploid Human Genome Assembly of East Asian Origin, (misc) bioRxivorg, 2025, DOI: 10.1101/2025.08.01.667781
  4. Chu et al., Direct Submission, Computational Biology, Beijing Institute of Genomics, Chinese Academy of Sciences / China National Center for Bioinformation. Submitted (16-AUG-2025). NGDC, Beijing, 100101, China.
  5. Cole,C.G. et al., Finishing the finished human chromosome 22 sequence, Genome Biol, vol. 9, no. 5, 2008, pp. R78-.
  6. Combriato G. and Klobeck H.G, V lambda and J lambda-C lambda gene segments of the human immunoglobulin lambda light chain locus are separated by 14 kb and rearrange by a deletion mechanism, Eur. J. Immunol, vol. 21, no. 6, 1991, pp. 1513-1522. PUBMED: 1904362
  7. Dariavach P. et al., Human immunoglobulin C lambda 6 gene encodes the Kern+Oz-lambda chain and C lambda 4 and C lambda 5 are pseudogenes, Proc. Natl. Acad. Sci. U.S.A, vol. 84, no. 24, 1987, pp. 9074-9078. PUBMED: 3122211
  8. He et al., T2T YAO: A Telomere to telomere Assembled Diploid Reference Genome for Han Chinese, Genomics Proteomics & Bioinformatics 21(6): 1085–1100 (2023), DOI: 10.1016/j.gpb.2023.08.001
  9. Hieter P.A. et al., Clustered arrangement of immunoglobulin lambda constant region genes in man, Nature, vol. 294, no. 5841, 1981, pp. 536-540. DOI: 10.1038/294536a0
  10. Kawasaki K. et al., One-megabase sequence analysis of the human immunoglobulin lambda gene locus, Genome Res, vol. 7, no. 3, 1997, pp. 250-261. PUBMED: 9074928
  11. Lander,E.S. et al., Initial sequencing and analysis of the human genome, International Human Genome Sequencing Consortium Nature, vol. 409, no. 6822, 2001, pp. 860-921.
  12. Nurk S. et al., The complete sequence of a human genome, Science, vol. 376, no. 6588, 2022, pp. 44-53. PUBMED: 35357919
  13. Poul M.A. et al., The IGLJ6 joining segment as a STS in the human immunoglobulin lambda light chain constant region gene locus (located at 22q11), Nucleic Acids Res, vol. 19, no. 17, 1991, pp. 4785-4785. DOI: 10.1093/nar/19.17.4785
  14. Udey J.A. and Blomberg B, Human lambda light chain locus: organization and DNA sequences of three genomic J regions, Immunogenetics, vol. 25, no. 1, 1987, pp. 63-70. DOI: 10.1007/BF00768834
  15. Udey J.A. and Blomberg B, Intergenic exchange maintains identity between two human lambda light chain immunoglobulin gene intron sequences, Nucleic Acids Res, vol. 16, no. 7, 1988, pp. 2959-2969. DOI: 10.1093/nar/16.7.2959
  16. Vasicek T.J. and Leder P, Structure and expression of the human immunoglobulin lambda genes, J. Exp. Med, vol. 172, no. 2, 1990, pp. 609-620. DOI: 10.1084/jem.172.2.609