IMGT Repertoire (IG and TR)

The position 3' end is determined by IMGT/JunctionAnalysis by comparison with the *01 allele. Note that the percentage of identity is evaluated by comparison with ethe closest allele identified by IMGT/V-QUEST
The last codon of IMGT_CDR3 of the V-REGION is a STOP-CODON, which may disappear during rearrangement
Pseudogene because of no L-PART1, frameshift in V-EXON
Pseudogene because of STOP-CODON in L-PART1, gat instead of ggt in DONOR_SPLICE, Frameshift in V-EXON
Pseudogene because of STOP-CODON in IMGT-FR2 of V-REGION
STOP-CODON in V-REGION
No L-PART1, no 1st-CYS, no 2nd-CYS
Pseudogene because of frameshift in V-EXON
Frameshift in IMGT-FR1 of V-REGION, STOP-CODON in IMGT-FR3 of V-REGION
STOP-CODON in V-REGION, Frameshift in V-REGION
STOP-CODON in V-REGION, frameshift in IMGT-FR3 of V-REGION
Pseudogene because of STOP-CODON in IMGT-FR3
STOP-CODON in V_REGION, frameshift in V-REGION
pseudogene because of frameshift in V-REGION
B10.A and B10.S[9R] are congenics strains, B10 is the abbreviated symbol of C57BL/10.
V-EXON is partial: no L-PART2.
V-REGION is partial: AA 1 to 3 are absent (partial FR1-IMGT).
CI27 and ER34 are wild mice.
V-REGION is partial: AA 1 and 2 are absent (partial FR1-IMGT).
V-GENE is partial: no L-PART1, no L-PART2.
In the TRB locus the TRBV14 gene is localised 3' from the TRBC2 gene and is in an inverted orientation of transcription.

IMGT references: ↑

Barth R.K. et al., The murine T-cell receptor uses a limited repertoire of expressed V beta gene segments, Nature, vol. 316, no. 6028, 1985, pp. 517-523. DOI: 10.1038/316517a0
Behlke M.A, Unpublished.
Behlke M.A. and Loh D.Y, Alternative splicing of murine T-cell receptor beta-chain transcripts, Nature, vol. 322, no. 6077, 1986, pp. 379-382. DOI: 10.1038/322379a0
Behlke M.A. et al., Murine T-cell receptor mutants with deletions of beta-chain variable region genes, Proc. Natl. Acad. Sci. U.S.A, vol. 83, no. 3, 1986, pp. 767-771. PUBMED: 3456168
Behlke M.A. et al., T-cell receptor beta-chain expression: dependence on relatively few variable region genes, Science, vol. 229, no. 4713, 1985, pp. 566-570. PUBMED: 3875151
Cazenave P.-A. et al., V beta 17 gene polymorphism in wild-derived mouse strains: two amino acid substitutions in the V beta 17 region greatly alter T cell receptor specificity, Cell, vol. 63, no. 4, 1990, pp. 717-728. DOI: 10.1016/0092-8674(90)90138-5
Chen F. et al., Differential transcriptional regulation of individual TCR V beta segments before gene rearrangement, J. Immunol, vol. 166, no. 3, 2001, pp. 1771-1780. PUBMED: 11160223
Chien Y.-H. et al., Somatic recombination in a murine T-cell receptor gene, Nature, vol. 309, no. 5966, 1984, pp. 322-326. DOI: 10.1038/309322a0
Chou H.S. et al., Tandem linkage and unusual RNA splicing of the T-cell receptor beta-chain variable-region genes, Proc. Natl. Acad. Sci. U.S.A, vol. 84, no. 7, 1987, pp. 1992-1996. PUBMED: 3470773
Church,D.M. et al., Lineage-specific biology revealed by a finished genome assembly of the mouse, PLoS Biol (2009), PUBMED: 19468303
Church,D.M. et al., Modernizing reference genome assemblies, PLoS Biol, vol. 9, no. 7, 2011, PUBMED: 21750661
Epplen J.T. et al., Change in antigen specificity of cytotoxic T lymphocytes is associated with the rearrangement and expression of a T-cell receptor beta-chain gene, Proc. Natl. Acad. Sci. U.S.A, vol. 83, no. 12, 1986, pp. 4441-4445. PUBMED: 3487087
Fink P.J. et al., Correlations between T-cell specificity and the structure of the antigen receptor, Nature, vol. 321, no. 6067, 1986, pp. 219-226. DOI: 10.1038/321219a0
Hedrick S.M. et al., Sequence relationships between putative T-cell receptor polypeptides and immunoglobulins, Nature, vol. 308, no. 5955, 1984, pp. 153-158. DOI: 10.1038/308153a0
Hirama T. et al., Conserved V(D)J junctional sequence of cross-reactive cytotoxic T cell receptor idiotype and the effect of a single amino acid substitution, Eur. J. Immunol, vol. 21, no. 2, 1991, pp. 483-488. PUBMED: 1705514
Johnson N.A. et al., T cell receptor gene segment usage in a panel of hen-egg white lysozyme specific, I-Ak-restricted T helper hybridomas, J. Immunol, vol. 142, no. 9, 1989, pp. 3298-3304. PUBMED: 2468715
Kappler J.W. et al., A T cell receptor V beta segment that imparts reactivity to a class II major histocompatibility complex product, Cell, vol. 49, no. 2, 1987, pp. 263-271. DOI: 10.1016/0092-8674(87)90567-8
Kishihara K. et al., Functional alpha and beta T cell chain receptor messages can be detected in old but not in young athymic mice, Eur. J. Immunol, vol. 17, no. 4, 1987, pp. 477-482. PUBMED: 2883009
Louie M.C. et al., Identification and Characterization of New Murine T-Cell Receptor beta-chain Variable-Region (V-beta) Genes, J. Exp. Med, vol. 170, no. 6, 1989, pp. 1987-1998. DOI: 10.1084/jem.170.6.1987
Malissen M. et al., Direct evidence for chromosomal inversion during T-cell receptor beta-gene rearrangements, Nature, vol. 319, no. 6048, 1986, pp. 28-33. DOI: 10.1038/319028a0
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IMGT Repertoire (IG and TR)

Dynamic gene tables per IMGT group and per species (IMGT/GeneTables)

Gene table legend:

IMGT notes: ↑

IMGT references: ↑

IMGT Repertoire (IG and TR)

Dynamic gene tables per IMGT group and per species (IMGT/GeneTables)

Version 1.4

Version 1.3

Version 1.2

Version 1.1

Version 1.0

Gene table legend:

IMGT notes: ↑

IMGT references: ↑