IMGT Repertoire (IG and TR)

Fct: FUNCTIONALITY
- F: Functional
- P: Pseudogene
- ORF: Open Reading Frame
T: Transcribed
Pr: Translated into protein

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

Click on:

IMGT gene name to get the corresponding IMGT/GENE-DB entry,
IMGT allele name to see the corresponding Alignments of alleles,
accession number to get the corresponding IMGT/LIGM-DB entry.

IMGT gene name	IMGT allele name	Fct	T	Pr	Positions in the locus	IMGT/LIGM-DB reference sequences							IMGT/LIGM-DB sequences from the literature
IMGT gene name	IMGT allele name	Fct	T	Pr	Positions in the locus	Strain	Clone names	Exons	Accession numbers	Positions in the sequence	Secondary accession numbers		Strain	Clone names	Accession numbers			Positions in the sequence
	IGHM	IGHM*01	(F)								CH1	(3)			AB052744	[1]	c(s)
											CH2				AB052744	[1]	c(s)
											CH3	(1)			AB052744	[1]	c(s)
											CH4	(1)			AB052744	[1]	c(s)
											M1	(1)
											M2
		IGHM*02	(F)								CH1	(2)			AB052658	[1]	c
		IGHM*03	(F)								CH1	(3)			AF226284	[2]	c(s)
											CH2				AF226284	[2]	c(s)
											CH3	(1)			AF226284	[2]	c(s)
											CH4	(1)			AF226284	[2]	c(s)
	IGHD	IGHD*01	(F)								CH1	(2)			AB052658	[1]	c(m)
											CH2				AB052658	[1]	c(m)
											CH3				AB052658	[1]	c(m)
											CH4				AB052658	[1]	c(m)
											CH5				AB052658	[1]	c(m)
											CH6				AB052658	[1]	c(m)
											CH7				AB052658	[1]	c(m)
											M1				AB052658	[1]	c(m)
											M2				AB052658	[1]	c(m)

c: cDNA sequence.
(s) Transcript of a secreted chain.
(m) Transcript of a membrane chain.

IMGT notes:

(1) As in other Teleostei, CH3 is spliced to CH4 in secretory mu cDNA, whereas it is probably spliced to the M1 exon in membrane mu cDNA.
(2) As in other Teleostei, IGHM*02 CH1 is spliced to IGHD*01 CH1 in delta cDNA. Other exons of IGHM*02 have not yet been isolated.
(3) No delta cDNA spliced with IGHM*01 CH1 has been isolated (2).

IMGT references:

[1] Hirono I. et al., Unpublished (2001).
[2] Lee U.H. et al., Fish and Shellfish Immunol., 11, 537-540 (2001). PMID:11556482

See also (IMGT Scientific chart):

Created:: 23/10/2001
Last updated:: 22/09/2023
Authors:: Nathalie Bosc

IMGT Repertoire (IG and TR)

Gene table: Japanese flounder (Paralichthys olivaceus) IGHC