Here you are: IMGT Web resources > IMGT Repertoire (IG and TR) > 1. Locus and genes

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

Click on:

IMGT gene name IMGT allele name Fct T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Isolate Clone names Exons Accession numbers Positions in the sequence Secondary accession numbers Isolate Clone names Accession numbers Positions in the sequence
IGHA IGHA*01 F Ig alpha CH1 X53704 [2] X53385 [1] (2)
H+CH2 (1) X53704 [2] X53385 [1] (2)
CH3(including CHS) X53704 [2]
M
IGHA1 IGHA1*01 F AG05252 CM054644.1 CH1 IMGT000144 MAP 1600245..1600550
H+CH2 (1) IMGT000144 MAP 1600761..1601114
CH3(including CHS) IMGT000144 MAP 1601338..1601729
M IMGT000144 MAP 1604334..1604545
IGHA2 IGHA2*01 F AG05252 CM054644.1 CH1 IMGT000144 MAP 1726937..1727242
H+CH2 (1) IMGT000144 MAP 1727456..1727776
CH3(including CHS) IMGT000144 MAP 1728000..1728391
M IMGT000144 MAP 1730935..1731146
IGHD IGHD*01 P (3) AG05252 CM054644.1 CH1 IMGT000144 MAP 1431721..1432032
H1 IMGT000144 MAP 1432497..1432598
H2 IMGT000144 MAP 1435582..1435650
CH2 IMGT000144 MAP 1436386..1436709
CH3 IMGT000144 MAP 1436920..1437243
CHS IMGT000144 MAP 1439187..1439212
M1 IMGT000144 MAP 1440016..1440173
M2 IMGT000144 MAP 1440458..1440463
IGHE IGHE*01 F IgE CH1 M15399 [3]
CH2 M15399 [3]
CH3 M15399 [3]
CH4(including CHS) M15399 [3]
M1
M2
IGHE1 IGHE1*01 F AG05252 CM054644.1 CH1 IMGT000144 MAP 1587328..1587636
CH2 IMGT000144 MAP 1587842..1588162
CH3 IMGT000144 MAP 1588249..1588572
CH4 IMGT000144 MAP 1588652..1588974
CHS IMGT000144 MAP 1588975..1588980
M1 IMGT000144 MAP 1591059..1591180
M2 IMGT000144 MAP 1591265..1591345
IGHE2 IGHE2*01 F AG05252 CM054644.1 CH1 IMGT000144 MAP 1714089..1714397
CH2 IMGT000144 MAP 1714602..1714922
CH3 IMGT000144 MAP 1715009..1715332
CH4 IMGT000144 MAP 1715412..1715734
CHS IMGT000144 MAP 1715735..1715740
M1 IMGT000144 MAP 1717818..1717939
M2 IMGT000144 MAP 1718024..1718104
IGHG1 IGHG1*01 F IGHG1 CH1 AF300428 [4] (2)
H AF300428 [4] (2)
CH2 AF300428 [4] (2)
CH3(including CHS)
M1
M2
IGHG1*02 F IGHG1 CH1 AF300429 [4] (2)
H AF300429 [4] (2)
CH2 AF300429 [4] (2)
CH3(including CHS)
M1
M2
IGHG1*01 F AG05252 CM054644.1 CH1 IMGT000144 MAP 1565055..1565348
H IMGT000144 MAP 1565741..1565785
CH2 IMGT000144 MAP 1565904..1566233
CH3(including CHS) IMGT000144 MAP 1566331..1566650
M1 IMGT000144 MAP 1567943..1568073
M2 IMGT000144 MAP 1569473..1569553
IGHG2 IGHG2*01 F IGHG2 CH1 AF300426 [4] (2)
H AF300426 [4] (2)
CH2 AF300426 [4] (2)
CH3(including CHS)
M1
M2
IGHG2*02 F IGHG2 CH1 AF300427 [4] (2)
H AF300427 [4] (2)
CH2 AF300427 [4] (2)
CH3(including CHS)
M1
M2
IGHG2*01 ORF (4) AG05252 CM054644.1 CH1 IMGT000144 MAP 1667768..1668049
H IMGT000144 MAP 1668441..1668491
CH2 IMGT000144 MAP 1668610..1668939
CH3(including CHS) IMGT000144 MAP 1669037..1669356
M1 IMGT000144 MAP 1670649..1670779
M2 IMGT000144 MAP 1671770..1671850
IGHG3 IGHG3*01 F IGHG3 CH1 AF300451 [4] (2)
H1 AF300451 [4] (2)
H2 AF300451 [4] (2)
H3 AF300451 [4] (2)
CH2 AF300451 [4] (2)
CH3(including CHS)
M1
M2
IGHG3*02 F IGHG3 CH1 AF300452 [4] (2)
H1 AF300452 [4] (2)
H2 AF300452 [4] (2)
H3 AF300452 [4] (2)
CH2 AF300452 [4] (2)
CH3(including CHS)
M1
M2
IGHG3*03 F IGHG3 CH1 AF300453 [4] (2)
H1 AF300453 [4] (2)
H3 AF300453 [4] (2)
CH2 AF300453 [4] (2)
CH3(including CHS)
M1
M2
IGHG3A*01 F AG05252 CM054644.1 CH1 IMGT000144 MAP 1509047..1509340
H1 IMGT000144 MAP 1509733..1509783
H2 IMGT000144 MAP 1509927..1509971
CH2 IMGT000144 MAP 1510090..1510419
CH3(including CHS) IMGT000144 MAP 1510517..1510836
M1 IMGT000144 MAP 1512130..1512260
M2 IMGT000144 MAP 1515070..1515150
IGHG3B*01 ORF (5) AG05252 CM054644.1 CH1 IMGT000144 MAP 1535376..1535669
H1 IMGT000144 MAP 1536062..1536112
H2 IMGT000144 MAP 1536256..1536300
H3 IMGT000144 MAP 1536452..1536496
CH2 IMGT000144 MAP 1536615..1536944
CH3(including CHS) IMGT000144 MAP 1537042..1537361
M1 IMGT000144 MAP 1538636..1538766
M2 IMGT000144 MAP 1541186..1541266
IGHG4 IGHG4*01 F AG05252 CM054644.1 CH1 IMGT000144 MAP 1686486..1686779
H IMGT000144 MAP 1687172..1687216
CH2 IMGT000144 MAP 1687335..1687664
CH3(including CHS) IMGT000144 MAP 1687762..1688081
M1 IMGT000144 MAP 1689375..1689505
M2 IMGT000144 MAP 1690388..1690468
IGHGP IGHGP*01 F AG05252 CM054644.1 CH1 IMGT000144 MAP 1641944..1642237
H IMGT000144 MAP 1642630..1642674
CH2 IMGT000144 MAP 1642793..1643122
CH3(including CHS) IMGT000144 MAP 1643220..1643539
M1 IMGT000144 MAP 1644835..1644965
M2 IMGT000144 MAP 1648148..1648228
IGHM IGHM*01 F AG05252 CM054644.1 CH1 IMGT000144 MAP 1421568..1421879
CH2 IMGT000144 MAP 1421970..1422305
CH3 IMGT000144 MAP 1422551..1422868
CH4(including CHS) IMGT000144 MAP 1423048..1423439
M1 IMGT000144 MAP 1425513..1425628
M2 IMGT000144 MAP 1425802..1425807
IMGT notes:
  1. (1) In the IGHA gene, the hinge (H) and CH2 are joined in a single exon.
  2. (2) Partial C-GENE: CH1 is partial in 5' and CH2 is partial in 3'.
  3. (3) frameshift in CH1
  4. (4) deletions: 4 AA are missing in CH1
  5. (5) noncanonical DONOR-SPLICE: ngg instead of ngt
IMGT references:
  1. [1] Kawamura S. et al., J. Mol. Biol., 215, 201-206 (1990). PMID:2120447
  2. [2] Kawamura S. et al., Mol. Biol. Evol., 8, 743-752 (1991). PMID:1775062
  3. [3] Sakoyama Y. et al., Proc. Natl. Acad. Sci. U.S.A., 84, 1080-1084 (1987). PMID:3103123
  4. [4] Fortenfant F. et al., Unpublished (2002).
Created:
12/11/2002
Last updated:
26/12/2023
Authors:
Nathalie Bosc and Shamsa Batool