IMGT Repertoire (IG and TR)

Fct: FUNCTIONALITY
- F: Functional
- P: Pseudogene
- ORF: Open Reading Frame
T: Transcribed
Pr: Translated into protein

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

Click on:

IMGT gene name to get the corresponding IMGT/GENE-DB entry,
IMGT allele name to see the corresponding Alignments of alleles,
accession number to get the corresponding IMGT/LIGM-DB entry.

IMGT gene name	IMGT allele name	Fct	T	Pr	Positions in the locus	IMGT/LIGM-DB reference sequences							IMGT/LIGM-DB sequences from the literature
IMGT gene name	IMGT allele name	Fct	T	Pr	Positions in the locus	Strain	Clone names	Exons	Accession numbers	Positions in the sequence	Secondary accession numbers		Strain				Clone names	Accession numbers	Positions in the sequence
	IGHA1	IGHA1*01	F							Ig alpha-1	CH1		X53702	[1]						X08041	[2]	(2)
											H+CH2	(1)	X53702	[1]						X08041	[2]	(2)
											CH3(including CHS)		X53702	[1]
											M
	IGHA2	IGHA2*01	F							Ig alpha-2	CH1		X53706	[1]						X08040	[2]	(2)
											H+CH2	(1)	X53706	[1]						X08040	[2]	(2)
											CH3(including CHS)		X53706	[1]
											M
	IGHE	IGHE*01	F							IgE	CH1		M15398	[3]
											CH2		M15398	[3]
											CH3		M15398	[3]
											CH4(including CHS)		M15398	[3]
											M1
											M2
	IGHG1	IGHG1*01	(F)							IgG	CH1		X65284	[4]		c
											H		X65285	[4]		c
											CH2		X61311	[4]		c
											CH3(including CHS)		X61310	[4]	(3)	c
											M1
											M2
		IGHG1*02	F							IGHG1	CH1		AF300437	[5]	(2)
											H		AF300437	[5]	(2)
											CH2		AF300437	[5]	(2)
											CH3(including CHS)
											M1
											M2
	IGHG2	IGHG2*01	F							IGHG2	CH1		AF300436	[5]	(2)
											H		AF300436	[5]	(2)
											CH2		AF300436	[5]	(2)
											CH3(including CHS)
											M1
											M2
	IGHG3	IGHG3*01	F							IGHG3	CH1		AF300434	[5]	(2)
											H1		AF300434	[5]	(2)
											H2		AF300434	[5]	(2)
											CH2		AF300434	[5]	(2)
											CH3(including CHS)
											M1
											M2
		IGHG3*02	F							IGHG3	CH1		AF300435	[5]	(2)
											H1		AF300435	[5]	(2)
											H2		AF300435	[5]	(2)
											CH2		AF300435	[5]	(2)
											CH3(including CHS)
											M1
											M2
	IGHG4	IGHG4*01	F							IGHG4	CH1		AF300432	[5]	(2)					AF300433	[5]	(2)
											H		AF300432	[5]	(2)					AF300433	[5]	(2)
											CH2		AF300432	[5]	(2)					AF300433	[5]	(2)
											CH3(including CHS)
											M1
											M2
	IGHGP	IGHGP*01	F							IGHGP	CH1		AF300430	[5]	(2)
											H		AF300430	[5]	(2)
											CH2		AF300430	[5]	(2)
											CH3(including CHS)
											M1
											M2
		IGHGP*02	F							IGHGP	CH1		AF300431	[5]	(2)
											H		AF300431	[5]	(2)
											CH2		AF300431	[5]	(2)
											CH3(including CHS)
											M1
											M2

c: cDNA sequence.

IMGT notes:

(1) In the IGHA gene, the hinge (H) and CH2 are joined in a single exon.
(2) Partial C-GENE: CH1 is partial in 5' and CH2 is partial in 3'.
(3) Partial CH3 in 3'.

IMGT references:

[1] Kawamura S. et al., J. Biol. Chem., 267, 7359-7367 (1992). PMID:1559979
[2] Ueda S. et al., J. Mol. Evol., 27, 77-83 (1988). PMID:3133489
[3] Sakoyama Y. et al., Proc. Natl. Acad. Sci. U.S.A., 84, 1080-1084 (1987). PMID:3103123
[4] Ehrlich P.H. et al., Mol. Immunol., 28, 319-322 (1991). PMID:2062315
[5] Fortenfant F. et al., Unpublished (2002).

See also (IMGT Scientific chart):

Created:: 12/11/2002
Last updated:: 22/09/2023
Authors:: Nathalie Bosc

IMGT Repertoire (IG and TR)

Gene table: chimpanzee (Pan troglodytes) IGHC