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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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IMGT gene name IMGT allele name Fct R T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
IGHD1 IGHD1*01 F 1315 X13447 [1]
IGHD2 IGHD2*01 F 1315 X13447 [1]
IGHD3 IGHD3*01 (F) + + F101 X13449 [1] ~VDJ
IGHD4 IGHD4*01 F + + 1403 Z11777 [2] Z11780 [2] #c
HXIA X03750 [3]
1403 X15170 [1]
IGHD5 IGHD5*01 F + + 1403 Z11777 [2] Z11780 [2] #c
1403 X15173 [1] (1)
IGHD6 IGHD6*01 F 33141 Z11778 [2]
IGHD7 IGHD7*01 F 33141 Z11779 [2]
IGHD8 IGHD8*01 F + + 1113 Z11776 [2] Z11790 [2] #c
1113 X15172 [1]
IGHD9 IGHD9*01 F + + 1113 Z11776 [2] Z11790 [2] #c
1113 X15172 [1]
IGHD10 IGHD10*01 (F) + + 1320 X13448 [1] ~VDJ
IGHD11 IGHD11*01 F 2807 X15171 [1]
IGHD12 IGHD12*01 F 2807 X15174 [1]
IGHD13 IGHD13*01 (F) + + 12271 Z11781 [2] #c
IGHD14 IGHD14*01 (F) + + 12272 Z11782 [2] #c
IGHD15 IGHD15*01 (F) + + 12214 Z11783 [2] #c
IGHD16 IGHD16*01 (F) + + 12241 Z11784 [2] #c
IGHD17 IGHD17*01 (F) + + 12221 Z11785 [2] #c
IGHD18 IGHD18*01 (F) + + 12273 Z11786 [2] #c
IGHD19 IGHD19*01 (F) + + 12251 Z11787 [2] #c
IGHD20 IGHD20*01 (F) + + HN13 Z11788 [2] #c
IGHD21 IGHD21*01 (F) + + Z11789 [2] #c
IGHD22 IGHD22*01 (F) + + HN21 Z11791 [2] #c
IGHD23 IGHD23*01 (F) + + HN72 Z11792 [2] #c
IGHD24 IGHD24*01 (F) + + HC-3 X03748 [3] #c

#c: rearranged cDNA.
~VDJ: VDJ genomic DNA rearranged in the cassette.

IMGT notes:
  1. (1) In this sequence, only one nucleotide is different from the reference sequence.
IMGT references:
  1. [1] Kokubu F. et al., EMBO J., 7, 3413-3422 (1988). PMID:3145194
  2. [2] Hinds-Frey K.R. et al., J. Exp. Med., 178, 815-824 (1993). PMID:8350055
  3. [3] Hinds K.R. et al., Nature, 320, 546-549 (1986). PMID:3083268
Created:
31/01/2002
Last updated:
22/09/2023
Authors:
Dominique Scaviner