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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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Click here for the Correspondence between nomenclatures: Mouse (Mus musculus) TRG.

IMGT subgroup IMGT gene name IMGT allele name Fct Chromosomal localization R T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
TRGV1 TRGV1 TRGV1*01 F 13 (10.0 cM) BALB/c V10.8B M12832 [1] fin
TRGV1*02 F 13 (10.0 cM) Vgamma1.1 AF021335 [9] C57BL/6J IMGT000133 [18] MAP 171975-172452 (16)
TRGV1*03 (F) 13 (10.0 cM) + BALB/c M26763 [3] #g
TRGV1*04 (F) 13 (10.0 cM) + + C57BL/10 V10.8B X03802 [5] #c
TRGV1*05 (F) 13 (10.0 cM) + + AKR Vgamma1 U07554 [10] (10) #c
TRGV1*06 (F) 13 (10.0 cM) + + DBA/2 M77017 [11] (3) #c
TRGV1*07 (F) 13 (10.0 cM) + + C57BL/10 Vgamma1 Z22847 [12] (3) #c
TRGV1*08 (F) 13 (10.0 cM) + + L-I Z48588 [13] (3) #c
TRGV2 (13) TRGV2*01 F 13 (10.0 cM) + + BALB/c V10.8A M12831 [1] Vgamma1.2 AF021335 [9]
BALB/c L15321 [6] (4)
C57BL/6J IMGT000133 [18] MAP complement(168380--168901) (16)
TRGV2*02 (F) 13 (10.0 cM) + + M54996 [14] #c
TRGV2*03 (F) 13 (10.0 cM) + + BALB/c X03985 [15] #c
TRGV2*04 (F) 13 (10.0 cM) + + L-I Z48589 [13] (3) #c
TRGV2*05 [F] 13 (10.0 cM) AKR Vgamma2 U07555 [10] (7) °
TRGV3 TRGV3*01 F 13 (10.0 cM) + + V5S3 AF037352 [8] C57BL/6J IMGT000133 [18] MAP 74804-75299 (16)
TRGV3*02 F 13 (10.0 cM) + BALB/c V5.7 M12833 [1] (1) M26764 [3] #g
TRGV3*03 [F] 13 (10.0 cM) AKR Vgamma3 U07556 [10] (7) °
TRGV2 TRGV4 TRGV4*01 F 13 (10.0 cM) V3S1 AF037352 [8] (14) C57BL/6 X62545 [7] (2,14)
5'UTR M13335 [4]
M13336 [4] #g
C57BL/6J IMGT000133 [18] MAP 16940-17504 (16)
TRGV4*02 (F) 13 (10.0 cM) + + BALB/c M30171 [2] (3) #c
TRGV4*03 (F) 13 (10.0 cM) + C57BL/10 M26765 [3] (12,15) #g
TRGV4*04 (F) 13 (10.0 cM) + + DBA/2 Vgamma4 Z12299 [12] (6,15) #c
TRGV4*05 (F) 13 (10.0 cM) + + L-I Z48590 [13] (6,15) #c
TRGV3 TRGV5 TRGV5*01 F 13 (10.0 cM) + + V1S1 AF037352 [8] C57BL/6 X62546 [7] (11)
C57BL/6J IMGT000133 [18] MAP 24237-24723 (16)
TRGV4 TRGV6 TRGV6*01 F 13 (10.0 cM) C57BL/6 Vg6 D29793 [16]
TRGV6*02 F 13 (10.0 cM) V2S1 AF037352 [8] C57BL/6J IMGT000133 [18] MAP 22327-22927 (16)
TRGV6*03 (F) 13 (10.0 cM) + BALB/c V4 M13338 [4] (8) #g
TRGV6*04 (F) 13 (10.0 cM) + + L-I Z48592 [13] (5) #c
TRGV5 TRGV7 TRGV7*01 F 13 (10.0 cM) + + C57BL/6 Vg7 D29794 [16] AKR X05501 [17] #g
TRGV7*02 F 13 (10.0 cM) + + V4S1 AF037352 [8] C57BL/6 X62544 [7] (9)
TRGVA TRGVA TRGVA*01 P (18) 13 (10.0 cM) C57BL/6J IMGT000113 [18]

#c: rearranged cDNA.
#g: rearranged DNA.
°: DNA genomic sequence, but not known as being germline or rearranged.

IMGT notes:
  1. (1) V-GENE is partial: no L-PART1 and no V-NONAMER, and V-REGION is partial: AA 1 to 80 are absent (no FRI-IMGT, no CDR1-IMGT, no FR2-IMGT, no CDR2-IMGT and partial FR3-IMGT).
  2. (2) V-REGION is partial: AA 1 to 42 are absent (no FR1-IMGT, no CDR1-IMGT and partial FR2-IMGT).
  3. (3) V-REGION is partial: AA 1 to 2 are absent (partial FR1-IMGT).
  4. (4) V-REGION is partial: AA 43 to 108 are absent (partial FR2-IMGT, no CDR2-IMGT, no FR3-IMGT and no CDR3-IMGT).
  5. (5) V-REGION is partial: AA 1 to 4 are absent (partial FR1-IMGT).
  6. (6) V-REGION is partial: AA 1 to 5 are absent (partial FR1-IMGT).
  7. (7) V-REGION is partial: AA 1 to 9 are absent (partial FR1-IMGT), AA 91 to 104 are missing (partial FR3-IMGT), and no CDR3-IMGT.
  8. (8) V-J-GENE is partial: no L-PART1 and partial rearranged CDR3-IMGT.
  9. (9) V-REGION is partial: AA 1 to 84 are absent (no FR1-IMGT, no CDR1-IMGT, no FR2-IMGT, no CDR2-IMGT and partial FR3-IMGT), and partial sequence which could not be assigned to a given allele.
  10. (10) V-J-GENE is partial: no L-PART1.
  11. (11) V-REGION is partial: AA 1 to 80 are absent (no FR1-IMGT, no CDR1-IMGT, no FR2-IMGT, no CDR2-IMGT and partial FR3-IMGT).
  12. (12) V-REGION is partial: AA 1 to 11 are absent (partial FR1-IMGT).
  13. (13) The TRGV2 gene and the associated TRGJ2 and TRGC2 genes are in inverted orientation of transcription, compared to the other genes of the mouse TRG locus.
  14. (14) The last codon of the CDR3-IMGT of the germline V-REGION is a STOP-CODON which may disappear during rearrangements.
  15. (15) The last codon of the CDR3-IMGT of the germline V-REGION which is a STOP-CODON (see Germline Gene Tables) has been kept during the rearrangement in these sequences.
  16. (16) Position of L-V-GENE-UNIT
  17. (17) Position of V-REGION
  18. (18) no L-PART2, truncated pseudogene not assigned to subgroups with functional genes, truncated pseudogene not assigned to subgroups with functional genes, no V-RS
IMGT references:
  1. [1] Hayday A.C. et al., Cell, 40, 259-269 (1985). PMID:3917858
  2. [2] Heilig J.S. and Tonegawa S., Nature, 322, 836-840 (1986). PMID:2943999
  3. [3] Traunecker A. et al., EMBO J., 5, 1589-1593 (1986). PMID:3017705
  4. [4] Garman R.D. et al., Cell, 45, 733-742 (1986). PMID:3486721
  5. [5] Iwamoto A. and Yamagishi H., J. Exp. Med., 163, 1203-1212 (1986). PMID:3486244
  6. [6] Kuziel W.A. et al., Immunogenetics, 39, 296-297 (1994). PMID:8119739
  7. [7] Iwasato T. and Yamagishi H., Eur. J. Immunol., 22, 101-106 (1992). PMID:1309699
  8. [8] Zhou Q. et al., Unpublished.
  9. [9] Parlee M.J. et al., Unpublished.
  10. [10] Kalataradi H. et al., J. Immunol., 153, 1455-1465 (1994). PMID:8046225
  11. [11] Roger T. and Seman M., Immunogenetics, 36, 67-69 (1992). PMID:1534064
  12. [12] Roger T. et al., Immunogenetics, 39, 68-70 (1994). PMID:8225440
  13. [13] Roger T. et al., Immunogenetics, 43, 165-166 (1996). PMID:8550103
  14. [14] Yoshikai Y. et al., Nature, 324, 482-485 (1986). PMID:3785427
  15. [15] Rupp F. et al., Nature, 321, 876-878 (1986). PMID:3014341
  16. [16] Ishimi Y. et al., Immunogenetics, 43, 68-71 (1996). PMID:8537125
  17. [17] Pelkonen, J. et al., EMBO J., 6, 1941-1944 (1987). PMID:3653075
  18. [18] Church,D.M. et al., PLoS Biol. 7 (5), e1000112 (2009). PMID:19468303
Created:
18/04/1997
Last updated:
22/09/2023
Authors:
Nathalie Pallarès, Dominique Scaviner, Géraldine Folch and Marie-Paule Lefranc