IMGT Repertoire (IG and TR)

Fct: FUNCTIONALITY
- F: Functional
- P: Pseudogene
- ORF: Open Reading Frame
T: Transcribed
Pr: Translated into protein

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

Click on:

IMGT gene name to get the corresponding IMGT/GENE-DB entry,
IMGT allele name to see the corresponding Alignments of alleles,
accession number to get the corresponding IMGT/LIGM-DB entry.

IMGT gene name	IMGT allele name	Fct	T		Pr	Positions in the locus	IMGT/LIGM-DB reference sequences							IMGT/LIGM-DB sequences from the literature
IMGT gene name	IMGT allele name	Fct	T		Pr	Positions in the locus	Strain	Clone names	Exons	Accession numbers	Positions in the sequence	Secondary accession numbers		Strain				Clone names	Accession numbers	Positions in the sequence
	IGHM1	IGHM1*01	F								cos5	CH1		AF003844	[1]
												CH2		AF003845	[1]
												CH3		AF003846	[1]
												CH4(including CHS)		AF003847	[1]
	IGHM2	IGHM2*01	F								20182	CH1		AF003862	[1]
												CH2		AF003863	[1]
												CH3		AF003864	[1]
												CH4(including CHS)		AF003865	[1]
	IGHM3	IGHM3*01	F								20442	CH1		AF003839	[1]		c(s)
												CH2		AF003839	[1]		c(s)
												CH3		AF003839	[1]		c(s)
												CH4(including CHS)		AF003839	[1]		c(s)
	IGHM4	IGHM4*01	F								3171	CH1		AF004359	[1]		c(s)
												CH2		AF004359	[1]		c(s)
												CH3		AF004359	[1]		c(s)
												CH4(including CHS)		AF004359	[1]		c(s)
	IGHM5	IGHM5*01	F								3173	CH1		AF004360	[1]		c(m)
												CH2		AF004360	[1]		c(m)
												CH3		AF004360	[1]		c(m)
												CH4		AF004360	[1]		c(m)
												M1		AF004360	[1]	(2)	c(m)
												M2	(2)
	IGHM6	IGHM6*01	F								3631	CH4(including CHS)		AF003852	[1]	(1)
	IGHM7	IGHM7*01	P	(3)							20457	CH4(including CHS)		AF003851	[1]
	IGHM8	IGHM8*01	F								3430	CH1		AF003853	[1]		c(m)

c: cDNA sequence.
(s): transcript of a secreted chain.
(m): transcript of a membrane chain.

IMGT notes:

(1) C-REGION is partial: CHS is partial in 3'.
(2) C-REGION is partial: M1 is partial in 3'.
(3) STOP-CODON in the C-REGION (4 nucleotides DELETION), leading to a frameshift.

IMGT references:

[1] Rast J.P. et al., Immunogenetics, 47, 234-245 (1998). PMID:9435342

See also (IMGT Scientific chart):

Created:: 31/01/2002
Last updated:: 22/09/2023
Authors:: Dominique Scaviner

IMGT Repertoire (IG and TR)

Gene table: spotted ratfish (Hydrolagus colliei) IGHC