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"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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The Zebrafish (Danio rerio) IGI constant genes and alleles find on cDNA and not assigned to germline have a temporary designation based on the IMGT gene name nomenclature rules. They are designated by the locus three letter root, followed by the letter C, the subgroup number, the letter S and a number

Positions in the sequence: limits from the first nucleotide of C-REGION to the last nucleotide.

IMGT gene name IMGT allele name Fct T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Exons Accession numbers Positions in the sequence Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence
IGIC1 IGIC1*01 F DKEY-158E13 BX571825 [1] 156247-156558
IGIC2 IGIC2*01 P DKEY-158E13 BX571825 [1] (1) 151365-151684
IGIC3 IGIC3*01 F DKEY-158E13 BX571825 [1] 119652-119968
IGIC4 IGIC4*01 P DKEY-158E13 BX571825 [1] (1) 81299--84084
IGIC5 IGIC5*01 F DKEY-158E13 BX571825 [1] 77132-77448
IGIC6S1 IGIC6S1*01 (F) LC1_8 AF246185 [2] #c 412-750
IGIC6S2 IGIC6S2*01 (F) EF222424 [3] #c 326-626
IGIC7S1 IGIC7S1*01 (F) NLC3 AF246162 [2] #c 1708-2031
IGIC7S2 IGIC7S2*01 (F) EF222430 [3] #c 362-668
IGIC8S1 IGIC8S1*01 (F) LC1-7 AF246193 [2] #c 412-717

#c: rearranged cDNA.

IMGT notes:
  1. (1) Pseudogene because of frameshift and/or STOP-CODON.
IMGT references:
  1. [1] Marianes A.E. et al., Immunology, 132, 240-255 (2011). PMID:21070232
  2. [2] Haire R.N. et al., Immunogenetics, 51, 915-923 (2000). PMID:11003385
  3. [3] Zimmerman A.M. et al., Dev. Comp. Immunol., 32, 421-434 (2008). PMID:18022691
Created:
22/04/2003
Last updated:
22/09/2023
Authors:
Nathalie Bosc, Amandine Lacan