Here you are: IMGT Web resources > IMGT Repertoire (IG and TR) > 1. Locus and genes

"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.

Functionality is shown between parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

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IMGT gene name IMGT allele name Fct Haplotypes R T Pr Positions in the locus IMGT/LIGM-DB reference sequences IMGT/LIGM-DB sequences from the literature
Strain Clone names Accession numbers Positions in the sequence (J-REGION) Secondary accession numbers Strain Clone names Accession numbers Positions in the sequence (J-REGION)
IGKJ1-1 IGKJ1-1*01 ORF K1 b4 JK1 K01360 [1] (1) 482-519 JK1 X00231 [3]
K1 b4var IGKJ1 K01361 [2]
IGKJ1-1*02 ORF K1 b5 JK1 K01363 [4] (1) 137-174
K1 b95 M22541 [7]
IGKJ1-1*03 F K1 b9 JK1 M14067 [5] 160-197
IGKJ1-2 IGKJ1-2*01 F K1 b4 JK2 K01360 [1] 855-894 JK2 X00231 [3]
K1 b95 M22541 [7]
IGKJ1-2*02 F K1 b4var IGKJ2 K01361 [2] 1496-1535
IGKJ1-2*03 F K1 b5 + JK2 K01363 [4] 517-556
IGKJ1-2*04 F K1 b9 + JK2 M14067 [5] (2) 537-576
IGKJ1-3 IGKJ1-3*01 ORF K1 b4 JK3 K01360 [1] (3) 1140-1177 JK3 X00231 [3]
K1 b6 JK3 M37809 [6]
K1 b9 JK3 M14067 [5]
IGKJ1-3*02 ORF K1 b4var IGKJ3 K01361 [2] (3) 1782-1819
K1 b5 JK3 K01363 [4]
IGKJ1-3*03 ORF K1 b95 M22541 [7] (3) 802-839
IGKJ1-4 IGKJ1-4*01 ORF K1 b4 JK4 K01360 [1] (4) 1430-1467 JK4 X00231 [3]
K1 b4var IGKJ4 K01361 [2]
K1 b9 JK4 M14067 [5]
K1 b95 M22541 [7]
IGKJ1-4*02 ORF K1 b5 JK4 K01363 [4] (4) 1091-1128
IGKJ1-4*03 ORF K1 b6 JK4 M37809 [6] (4) 413-450
IGKJ1-5 IGKJ1-5*01 ORF K1 b4 JK5 K01360 [1] (5) 1722-1759 JK5 X00231 [3]
K1 b4var IGKJ5 K01361 [2]
K1 b6 JK5 M37809 [6]
K1 b95 M22541 [7]
IGKJ1-5*02 ORF K1 b5 JK5 K01363 [4] (5) 1389-1426
IGKJ1-5*03 ORF K1 b9 JK5 M14067 [5] (5) 1407-1444
IGKJ2-1 IGKJ2-1*01 F K2 JK1 X00232 [3] 159-196
IGKJ2-2 IGKJ2-2*01 F K2 JK2-4 X00232 [3] (6) 538-577
IGKJ2-3 IGKJ2-3*01 F K2 JK5 X00232 [3] 842-879
IMGT notes:
  1. (1) ORF because of deletions of one nucleotide in the J-NONAMER and eight nucleotides in the J-SPACER.
  2. (2) Since the STOP-CODON at the 5' end of the J-REGION can be deleted by rearrangement (for example the cDNA sequence K01359), the J-GENE is considered as functional.
  3. (3) ORF because the conserved J-PHE is missing.
  4. (4) ORF because of the J-SPACER is composed of only 14 pb.
  5. (5) ORF because of non canonical J-HEPTAMER and the GLY is replaced by a GLU.
  6. (6) The 5' and 3' part of the IGKJ2-2 sequence are similar to the 5' part of IGKJ1-2 and to the 3' part of IGKJ1-4, respectively.
IMGT references:
  1. [1] Emorine L. et al., Proc. Natl. Acad. Sci. U.S.A., 80, 5709-5713 (1983). PMID:6412231
  2. [2] Heidmann O. and Rougeon F., Cell, 34, 767-777 (1983). PMID:6313207
  3. [3] Emorine L. and Max E.E., Nucleic Acids Res., 11, 8877-8890 (1983). PMID:6324107
  4. [4] Emorine L. et al., Proc. Natl. Acad. Sci. U.S.A., 81, 1789-1793 (1984). PMID:6424123
  5. [5] Akimenko M.A. et al., Proc. Natl. Acad. Sci. U.S.A., 83, 5180-5183 (1986). PMID:3088570
  6. [6] Dreher K.L. et al., J.Immunol., 145, 325-330 (1990). PMID:2113556
  7. [7] Ayadi H. et al., Immunogenetics, 34, 201-207 (1991). PMID:1909995
Created:
29/05/1997
Last updated:
22/09/2023
Authors:
Manuel Ruiz, Fatena Bellahcene