IMGT Repertoire (RPI)

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Other B7 Family entries

Homo sapiens: B7A1, B7A2, B7H1, B7DC, B7H2, B7H3, B7H4
Mus musculus: B7A1, B7A2, B7H1, B7DC, B7H2, B7H4

IMGT RPI entry from gene to protein for Mus musculus B7H3

Citing IMGT RPI entry for B7H3

Duprat, E. et al. IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily, Recent Research Developments in Human Genetics, 2, 111-136 (2004)

with permission from Research Signpost

IMGT gene name and definition

IMGT gene name: Mus musculus B7H3
IMGT gene definition: CD276 molecule

Chromosomal localization

Chromosome: 9
Chromosomal localization: 9B

Gene exon/intron organization

Legend:

Length of the exons and introns are in base pairs.
Colors are according to IMGT Color menu for regions and domains

Number of alleles: 1

IMGT reference alleles

Allele names	Gene functionality	Strain	IMGT reference sequences
Allele names	Gene functionality	Strain	Exons	Accession numbers	Molecule type
B7H3*01	F	C57BL/6J	EX1-7	AY190318 [1]	cDNA

IMGT reference sequences (in FASTA format) for the allele(s): B7H3*01

Nucleotide sequence in FASTA format with gaps according to the IMGT unique numbering
Amino acid sequence in FASTA format with gaps according to the IMGT unique numbering
Nucleotide sequence in FASTA format without gaps
Amino acid sequence in FASTA format without gaps

Other sequences from the literature

Allele names	Gene functionality	Strain	IMGT reference sequences
Allele names	Gene functionality	Strain	Exons	Accession numbers	Molecule type
B7H3*01	F	NOD	EX1-7	AK155114	cDNA
		FVB/N	EX1-7	BC019436
			EX1-7	BC056608
			EX1-7	NM_133983

Corresponding protein database accession numbers

Allele name	Accession numbers		Number of amino acids	Protein isoform
Allele name	Nucleotide databases	Protein databases	Number of amino acids	Protein isoform
B7H3*01	AY190318	Tr:Q8VE98	317 aa	1
B7H3*01	NM_133983	NP_598744	317 aa	1

IMGT references:

[1] Suh W.K. et al. Natational Immunology 4, 899-906 (2003). PMID:12925852

Genomic sequence

Coding region sequence

The coding region (CODING-REGION) sequence starts from INIT-CODON (or its encoded amino acid) to STOP-CODON (not included).
The nucleotide sequence is extracted from cDNA (c) sequences and/or is built by artificial exon joining from genomic DNA (g) sequences. The amino acid sequence is the translation of the nucleotide sequence.

B7H3*01: AY190318(c)

Nucleotide sequence

1        atgcttcgag gatggggtgg ccccagtgtg ggtgtgtgtg tgcgcacagc actgggggtg

61       ctgtgcctct gcctcacagg agctgtggaa gtccaggtct ctgaagaccc cgtggtggcc

121      ctggtggaca cggatgccac cctacgctgc tccttttccc cagagcctgg cttcagtctg

181      gcacagctca acctcatctg gcagctgaca gacaccaaac agctggtgca cagcttcacg

241      gagggccggg accaaggcag tgcctactcc aaccgcacag cgctcttccc tgacctgttg

301      gtgcaaggca atgcgtcctt gaggctgcag cgcgtccgag taaccgacga gggcagctac

361      acctgctttg tgagcatcca ggactttgac agcgctgctg ttagcctgca ggtggccgcc

421      ccctactcga agcccagcat gaccctggag cccaacaagg acctacgtcc agggaacatg

481      gtgaccatca cgtgctctag ctaccagggc tatccggagg ccgaggtgtt ctggaaggat

541      ggacagggag tgcccttgac tggcaatgtg accacatccc agatggccaa cgagcggggc

601      ttgttcgatg ttcacagcgt gctgagggtg gtgctgggtg ctaacggcac ctacagctgc

661      ctggtacgca acccggtgtt gcagcaagat gctcacggct cagtcaccat cacagggcag

721      cccctgacat tcccccctga ggctctgtgg gtaaccgtgg ggctctctgt ctgtcttgtg

781      gtactactgg tggccctggc tttcgtgtgc tggagaaaga tcaagcagag ctgcgaggag

841      gagaatgcag gtgccgagga ccaggatgga gatggagaag gatccaagac agctctacgg

901      cctctgaaac cctctgaaaa caaagaagat gacggacaag aaattgcttg a

Nucleotide sequence in FASTA format (without gaps) B7H3*01

Amino acid sequence

1        MLRGWGGPSV GVCVRTALGV LCLCLTGAVE VQVSEDPVVA LVDTDATLRC SFSPEPGFSL

61       AQLNLIWQLT DTKQLVHSFT EGRDQGSAYS NRTALFPDLL VQGNASLRLQ RVRVTDEGSY

121      TCFVSIQDFD SAAVSLQVAA PYSKPSMTLE PNKDLRPGNM VTITCSSYQG YPEAEVFWKD

181      GQGVPLTGNV TTSQMANERG LFDVHSVLRV VLGANGTYSC LVRNPVLQQD AHGSVTITGQ

241      PLTFPPEALW VTVGLSVCLV VLLVALAFVC WRKIKQSCEE ENAGAEDQDG DGEGSKTALR

301      PLKPSENKED DGQEIA*

Amino acid sequence in FASTA format (without gap) B7H3*01

Legend:

Colors are according to IMGT Color menu for regions and domains
Nucleotide and amino acid letters (in bold) in purple, green or blue are according to IMGT Color menu for splicing types.

IMGT links

IMGT Repertoire

Chromosomal localization:
Alignment of alleles:
Protein displays:
IMGT Collier de perles: V-LIKE-DOMAIN on one layer, V-LIKE-DOMAIN on two layers, C-LIKE-DOMAIN on one layer, C-LIKE-DOMAIN on two layers

External links

Nomenclature

HGNC:

Genome databases

Entrez Gene: 102657
MGI: 2183926
GENATLAS:
GeneCards:
GDB:
OMIM:

Sequence databases

EMBL: AY190318, AK155114, BC019436, BC056608
GenBank: AY190318, AK155114, BC019436, BC056608
DDBJ: AY190318, AK155114, BC019436, BC056608
Swiss-Prot:
TrEMBL: Q8VE98
NCBI: NM_133983, NP_598744

Structure databases

PDB: