A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
- a or A
- adenine (purine base of DNA and RNA)
- AA
- amino acid
- Å
- angstrom (angström in French) (10-10 meter, 1 Å = 0.1 nm)
- Ab
- antibody
- ACPA
- anti-citrullinated protein/peptide antibody
- AICDA
- activation induced cytidine deaminase (previously: AID, HIGM2)
- AID
- see AICDA
- BcR
- B cell receptor (on the surface of mature B cells and memory B cells, comprising mIG associated to the CD19 signaling coreceptors (CD79A (Ig-alpha, mb-1) and CD79B (Ig-beta, B29) dimers)
- BER
- base excision repair
- BM
- bone marrow
- bp
- base pair
- BrMRBc
- bromelain-treated mouse red blood cells
- c or C
- cytosine (pyrimidine base of DNA and RNA)
- C
- constant
- CCP
- cyclic citrullinated (deiminated) peptide
CCP1, CCP2, CCP3: first, second, third generation anti-CCP assay
- cDNA
- complementary DNA
- CDR
- complementarity determining region
- CDR-IMGT
- complementarity determining region according to IMGT unique numbering
- CH
- immunoglobulin heavy constant exon or domain
- CLL
- chronic lymphocytic leukemia
- CNRS
- Centre National de la Recherche Scientifique
- CNS
- central nervous system
- CO
- connecting region, CONNECTING-REGION (IMGT label)
- CPT
- citrate/pyridoxal 5'-phosphate/Tris
- CSR
- class switch recombination
- CY
- CYTOPLASMIC-REGION (IMGT label)
- D
- diversity
- Da
- dalton (1 Da=1.66x10-24 g)
- dC
- deoxycytidine
- DCI
- Dénomination Commune Internationale (INN in English)
- DDBJ
- DNA DataBank of Japan (nucleotide sequence database)
- DSB
- double-strand break
- dsDNA
- double-stranded DNA
- dU
- deoxyuridine
- E
- enhancer
- EBV
- Epstein-Barr virus
- EDTA
- ethylenediamine tetraacetic acid
- EMBLBank
- European Molecular Biology Laboratory nucleotide sequence database
- ENA
- European Nucleotide Archive
- ER
- endoplasmic reticulum
- FAM
- fluorescein-5-carboxamide (or 5-carboxyfluorescein)
- FAQ
- frequently asked question
- Fc
- Fragment crystallisable (for IG)
- FL
- follicular lymphoma
- FnSF
- fibronectin superfamily
- FR
- framework region
- FR-IMGT
- framework region according to IMGT unique numbering
- Fv
- Fragment variable
- g or G
- guanine (purine base of DNA and RNA)
- Gb
- gigabase (109 bases; a billion bases). Unit of length of nucleic acids. For double-stranded DNA, 109 base pairs (see also kb, Mb)
- GC
- germinal center
- gDNA
- genomic DNA
- GEDI
- GenBank/ENA/DDBJ/IMGT/LIGM-DB (previously GenBank/EMBLBank/DDBJ/IMGT/LIGM-DB)
- GenBank
- US nucleotide sequence database
- HCV
- hepatitis C virus
- HGNC
- Human Genome Organisation (HUGO) Nomenclature Committee
- HLA
- human leucocyte antigen (human MHC)
- HUGO
- HUman Genome Organisation
- IG
- immunoglobulin (for locus, gene, chain or receptor). On mature and memory B cells, membrane IG is part of a B cell receptor BcR (BcR = mIG + CD79 signalling coreceptors)
- IG/TR
- IG and/or TR (see also IG, TR)
- Ig
- immunoglobulin (as part of a IG class name, e.g. IgM, or of a prefix Ig-like, IgSF), see also IG
- IGH
- IG heavy
- IGHV
- IG heavy variable
- IGK
- IG kappa
- IGKV
- IG kappa variable
- IGL
- IG lambda
- IGLV
- IG lambda variable
- IgSF
- immunoglobulin superfamily
- IMGT
- IMGT®, the international ImMunoGeneTics information system®
- INN
- International Nonproprietary Name (DCI in French)
- J
- joining
- kb
- kilobase (103 bases). Unit of length of nucleic acids (DNA or RNA). For double-stranded DNA, 103 base pairs (see also Mb, Gb)
- kDa
- kilodalton
- LIGM-DB
- Laboratoire d'ImmunoGénétique Moléculaire DataBase
(Immunoglobulin and T cell receptor sequence database), part of IMGT
- mAb
- monoclonal antibody
- Mb
- megabase (106 bases; a million bases). Unit of length of nucleic acids. For double-stranded DNA, 106 base pairs (see also kb, Gb)
- MH
- major histocompatibility (for gene, chain or receptor)
- MH1
- major histocompatibility class I (for gene, chain or receptor)
- MH2
- major histocompatibility class II (for gene, chain or receptor)
- MHC
- major histocompatibility complex (for locus). MHC-I, MHC-II and MHC-III for sections of the locus with clusters of MH1, MH2 and non-MH genes, respectively
- MhSF
- major histocompatibility superfamily
- mIG
- membrane IG (defined has having a transmembrane region TM, refers usually to IG on the B cell surface and part of the BcR).
If needed, localization can be added: surface mIG for mIG on cell surface or ER mIG for mIG on endoplasmic reticulum membrane.
- mIgM
- membrane IgM (also for the other classes e.g. mIgD and subclasses e.g. mIgG3)
- MMP
- matrix metalloproteinase
- MMR
- DNA mismatch repair
- Nb or nb
- number
- NGS
- next generation sequencing
- nm
- nanometer (10-9 meter, 1 nm = 10 Å) (better to use nm rather than Å)
- nt
- nucleotide
- OMIM
- Online Mendelian Inheritance in Man (MIM)
- OMS
- Organisation mondiale de la Santé (WHO in English)
- ORF
- open reading frame
- PB
- peripheral blood
- pMHC
- peptide-MHC complex
- PtC
- phosphatidyl choline
- r or R
- purine (purine base of DNA, a or g, or A or G)
- RA
- rheumatoic arthritis
- RBC
- red blood cell
- RF
- rheumatoid factor
- RPI
- related proteins of the immune system
- RS
- recombination signal
- S
- switch
- scFv
- single chain Fragment variable (for IG and TR)
- SE
- shared epitope (refers for HLA-DRB1 to the RAA pattern at positions 68-70,
according to the IMGT unique numbering for G-DOMAIN, but the use of SE for this pattern is
inappropriate and not recommended)
- SHM
- somatic hypermutation
- sIgM
- secreted IgM
- SLE
- systemic lupus erythematosus
- SRS
- Sequence Retrieval System, a database query system developed by EMBL
- ssDNA
- single-stranded DNA
- SSP-PCR
- sequence specific primer polymerase chain reaction
- t or T
- thymine (pyrimidine base of DNA)
- TAMRA
- 5-(or/and -6)-carboxytetramethylrhodamine
- TcR
- T cell receptor (on the surface of T cells, comprising one TR associated with the CD3 signalling coreceptors (CD3G and CD3D, CD3G and CD3E, and CD3Z dimers)
- TdT
- terminal deoxynucleotidyl transferase
- TM
- transmembrane region, TRANSMEMBRANE-REGION (IMGT label)
- TR
- T cell receptor (for locus, gene, chain or receptor). On T cells, TR is part of a T cell receptor TcR (TcR = TR+ CD3 signalling coreceptor)
- TRA
- TR alpha
- TRAV
- TR alpha variable
- TRB
- TR beta
- TRBV
- TR beta variable
- TRG
- TR gamma
- TRGV
- TR gamma variable
- TRD
- TR delta
- TRDV
- TR delta variable
- UDG
- uracil-DNA glycosylase
- V
- variable
- w or W
- a or t, or A or T, adenine or thymine
- WHO
- World Health Organization (OMS in French)
- y or Y
- pyrimidine (pyrimidine base of DNA, c or t, or C or T)
