Translocations and inversions: Human IGK

Translocations involving the IGK locus

Locus Chromosomal localization Translocation Other involved genes (1) Clinical entities (2)
IGK 2p11.2 t(2;3)(p11;q27) BCL6 non-Hodgkin lymphomas (NHL)
diffuse large cell lymphoma (DLCL) (mainly)
t(2;8)(p11;q24) MYC B cell acute lymphoblastic leukemia (B-ALL)
non-Hodgkin lymphomas (NHL), especially in the Burkitt lymphoma
t(2;18)(p12;q21) BCL2 B cell chronic lymphocytic leukemia (B-CLL)

IMGT notes:
(1) For the list of genes (other than IG or TR) involved in the translocations, click here.
(2) Information on clinical entities are from the literature and from the Atlas of Genetics and Cytogenetics in Oncology and Haematology. For a list of the clinical entities quoted in the translocation tables, click here.

Created: 23/11/2000
Last updated: Monday, 20-Jan-2020 21:00:49 CET
Author:Marie-Paule Lefranc
Editors: Sandrine Béranger and Céline Protat