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Citing this page: Lefranc, M.-P., Exp. Clin. Immunogenet., 18, 100-116 (2001) PMID: 11340299. pdf Lefranc, M.-P. and Lefranc, G., The Immunoglobulin FactsBook, Academic Press, London, 458 pages (2001). pdf

Human (Homo sapiens) IGH orphons on chromosome 15 (15q11.2)

Human IGH orphons on chromosome 15 (15q11.2)

The map scale is 10X that of the major IGH locus.
The boxes representing the genes are not to scale. Exons are not shown.
ORPHONs are designated by a number for the subgroup followed by a slash, OR (for ORPHON), the chromosome number, a hyphen and a specific gene number.
The relative localization, orientation and centromeric-telomeric position of the isolated orphons IGHV and duplicated clusters A et B are unknown.

Legend:
Colors are according to IMGT color menu.
The boxes representing the genes are not to scale. Exons are not shown.

More information:
References:
[1] Matsuda, F. et al., EMBO J., 7, 1047-1051 (1988).
[2] Nagaoka, H. et al., Genomics., 22, 189-197 (1994).
[3] Tomlinson, I.M. et al., Hum. Mol. Genet., 3, 853-860 (1994).