References:
Pallarès et al., Exp. Clin. Immunogenet., 15, 8-18 (1998).pdf
Williams, S.C., Frippiat, J.-P. et al. J. Mol. Biol., 264, 220-232 (1996). PubMed: 8951372
Kawasaki, K. et al. Genome Res., 7, 250-261 (1997). PubMed: 9074928
For a comparative repertoire between different assemblies' annotations, see: Human (Homo sapiens) IGL locus (on chromosome 2 on the long arm, at band 22q11.2) gene repertoire per assembly.

See also Potential germline repertoire: Human (Homo sapiens) IGLV anterior to November 2025.

Human (Homo sapiens) IGLV genes

The Human (Homo sapiens) IGL locus on chromosome 22 comprises 95 IGLV genes belonging to 11 IGLV subgroups and 7 clans:
IMGT group IMGT subgroup Functional ORF Pseudogene Total
IGLV IGLV1 5 1(+1)* 2(2:0)(+1(1:0))* 9
IGLV2 5 1 3(2:1) 9
IGLV3 7(+3)* 1 12(2:10)(+3(1:2))* 23
IGLV4 2(+1)* 0 2(2:0)(+1(0:1))* 5
IGLV5 4 (+1)* (+1(1:0))* 5
IGLV6 (+1)* 0 (+1(0:1))* 1
IGLV7 1(+1)* 0 1(0:1)(+1(0:1))* 3
IGLV8 1 0 0 1
IGLV9 (+1)* 0 (+1(0:1))* 1
IGLV10 (+1)* 0 1(0:1)(+1(1:0))* 2
IGLV11 0 (+1)* (+1(0:1))* 1
IGLV(I) 0 0 13(2:11) 13
IGLV(II) 0 0 3(0:3) 3
IGLV(III) 0 0 3(0:3) 3
IGLV(IV) 0 0 7(0:7) 7
IGLV(V) 0 0 3(0:3) 3
IGLV(VI) 0 0 3(0:3) 3
IGLV(VII) 0 0 3(0:3) 3
Total 25(+8)* 3(+3)* 56(+11)* 95
In the column 'Pseudogene', the number of pseudogenes with V-REGION in-frame and the number of pseudogenes with frameshift(s) are shown separated by two dots, between parentheses.
* An asterisk indicates that there are genes that have alleles with different functionalities:
- FUNCTIONAL or PSEUDOGENE (IGLV4-60, IGLV6-57, IGLV10-54, IGLV9-49, IGLV7-46, IGLV3-22, IGLV3-12, IGLV3-9).
- ORF or PSEUDOGENE (IGLV11-55, IGLV5-48, IGLV1-41)
** Two asterisks indicate allelic polymorphisms by insertion/deletion
As seen in the IGL Locus Representation IGLV genes are organised in three distinct V-CLUSTERS, A, B and C.

Human (Homo sapiens) IGLJ genes

The Human (Homo sapiens) IGL locus on chromosome 22 comprises 8 IGLJ genes belonging to 8 sets:
IMGT group IMGT set or subgroup (if any) Functional ORF Pseudogene Total
IGLJ IGLJ1 1 0 0 1
IGLJ2 1 0 0 1
IGLJ2A 1 0 0 1
IGLJ3 1 0 0 1
IGLJ4 0 1 0 1
IGLJ5 0 1 0 1
IGLJ6 1 0 0 1
IGLJ7 1 0 0 1
Total 6 2 0 8