Sheep (Ovis aries) TRBV genes
The sheep (
Ovis aries) TRB locus comprises 94 TRBV genes belonging to 26 TRBV subgroups:
The TRBV genes are localized in 3 V-CLUSTER:
- the 5' V-CLUSTER, classically in 5' of the TRBD, TRBJ and TRBC, includes 93 TRBV genes belonging to 25 subgroups
(45 genes are functional, 12 genes are ORF and 36 genes are pseudogenes)
- the 3' V-CLUSTER, downstream of the TRBC in inverted orientation, includes 1 TRBV gene (functional)
| Localization of the V-CLUSTER in the locus |
IMGT subgroup |
Functional |
ORF |
Pseudogene |
Total |
| 5' V-CLUSTER |
TRBV1 |
1 |
0 |
0 |
1 |
| TRBV2 |
1 |
0 |
0 |
1 |
| TRBV3 |
1 |
0 |
0 |
1 |
| TRBV4 |
1 |
0 |
0 |
1 |
| TRBV5 |
14 |
5 |
14 (4:10) |
33 |
| TRBV6 |
10 |
5 |
15 (7:8) |
30 |
| TRBV7 |
2 |
0 |
0 |
2 |
| TRBV8 |
0 |
0 |
1 (0:1) |
1 |
| TRBV10 |
0 |
0 |
1 (0:1) |
1 |
| TRBV11 |
0 |
0 |
1 (1:0) |
1 |
| TRBV12 |
1 |
1 |
0 |
2 |
| TRBV14 |
1 |
0 |
0 |
1 |
| TRBV15 |
1 |
0 |
0 |
1 |
| TRBV16 |
1 |
0 |
0 |
1 |
| TRBV18 |
0 |
0 |
1 (0:1) |
1 |
| TRBV19 |
0 |
1 |
0 |
1 |
| TRBV20 |
1 |
0 |
0 |
1 |
| TRBV21 |
5 |
0 |
1 (1:0) |
6 |
| TRBV22 |
0 |
0 |
1 (1:0) |
1 |
| TRBV24 |
1 |
0 |
0 |
1 |
| TRBV25 |
1 |
0 |
0 |
1 |
| TRBV26 |
1 |
0 |
0 |
1 |
| TRBV27 |
0 |
0 |
1 (0:1) |
1 |
| TRBV28 |
1 |
0 |
0 |
1 |
| TRBV29 |
1 |
0 |
0 |
1 |
| 3' V-CLUSTER |
TRBV30 |
1 |
0 |
0 |
1 |
| Total |
46 |
12 |
36 |
94 |
In the column 'Pseudogene', the number of pseudogenes with V-REGION in-frame and the number of pseudogenes with frameshift(s) are shown separated by two dots, between parentheses.
Sheep (Ovis aries) TRBD genes
The sheep (
Ovis aries) TRB locus comprises 3 TRBD genes belonging to 3 TRBD sets:
| IMGT group |
IMGT set or subgroup (if any) |
Functional |
ORF |
Pseudogene |
Total |
| TRBD |
TRBD1 |
1 |
0 |
0 |
1 |
| TRBD2 |
1 |
0 |
0 |
1 |
| TRBD3 |
1 |
0 |
0 |
1 |
| Total |
3 |
0 |
0 |
3 |
Sheep (Ovis aries) TRBJ genes
The sheep (
Ovis aries) TRB locus comprises 19 TRBJ genes belonging to 3 TRBJ sets:
| IMGT group |
IMGT set or subgroup (if any) |
Functional |
ORF |
Pseudogene |
Total |
| TRBJ |
TRBJ1 |
5 |
1 |
0 |
6 |
| TRBJ2 |
7 |
0 |
0 |
7 |
| TRBJ3 |
5 |
0 |
1 |
6 |
| Total |
17 |
1 |
1 |
19 |
More information:
Gene table: sheep (Ovis aries) TRBV
Gene table: sheep (Ovis aries) TRBD
Gene table: sheep (Ovis aries) TRBJ
Locus description: sheep (Ovis aries) TRB