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IMGT Repertoire (IG and TR)
Alignment of alleles: house mouse (Mus musculus) TRAV12D-2
When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
- Dots indicate gaps according to the IMGT unique numbering.
- Blanks at the 5' and/or 3' end indicate partial sequences.
- Asterisk (*) in the sequence indicate a STOP-CODON.
- Letters in red correspond to amino acids which are polymorphic in the other alleles.
- Colours are according to Color menu for mutations, Color menu for sequence alignments and Color menu for splicing types.
- The nucleotide (s) in bold and colored in purple (splicing frame 1) or green (splicing frame 2) from the DONOR splice site are added at the beginning of the following exon in order to obtain and to complete the first CODON of the DOMAIN or REGION resulting from the splicing site. These first CODONs are in bold and colored in purple (splicing frame 1) or green (splicing frame 2)
- N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown in green
Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.
1 2 3 4 5 6 7 8 8A 9 10 11 12 13 14 15 16 17 18 19 G D S V T Q T E G L V T L T E G L P V X04332 TRAV12D-2*01 F V-REGION gDNA gga gac tct gtg acc cag aca gaa ... ggc ctg gtc act ctc acc gag ggg ttg cct gtg K AC005402 TRAV12D-2*02 F V-REGION gDNA --- --- --a --- --- --- --- --- ... --- --- --- --- --- --- a-- --- --- --- --- K AE007512 TRAV12D-2*02 F V-REGION gDNA --- --- --a --- --- --- --- --- ... --- --- --- --- --- --- a-- --- --- --- --- K AE008684 TRAV12D-2*02 F V-REGION gDNA --- --- --a --- --- --- --- --- ... --- --- --- --- --- --- a-- --- --- --- --- K IMGT000082 TRAV12D-2*02 F V-REGION gDNA --- --- --a --- --- --- --- --- ... --- --- --- --- --- --- a-- --- --- --- --- X04330 TRAV12D-2*03 (F) V-REGION cDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- K M15063 TRAV12D-2*04 (F) V-REGION cDNA --- --- --a --- --- --- --- --- ... --- t-- --- --- --- --- a-- --- --- --- --- K M98569 TRAV12D-2*05 (F) V-REGION cDNA --- --- --- --- a-- --- --- --- --- ___________________CDR1-IMGT____________________ 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 M L N C T Y Q S T Y S P F L X04332 TRAV12D-2*01 F V-REGION gDNA atg ctg aac tgc acc tat cag agt act tac ... ... ... ... ... ... tca cct ttc ctt T AC005402 TRAV12D-2*02 F V-REGION gDNA --- --- --- --- --- --- --- -c- --- --- ... ... ... ... ... ... --- --- --- --- T AE007512 TRAV12D-2*02 F V-REGION gDNA --- --- --- --- --- --- --- -c- --- --- ... ... ... ... ... ... --- --- --- --- T AE008684 TRAV12D-2*02 F V-REGION gDNA --- --- --- --- --- --- --- -c- --- --- ... ... ... ... ... ... --- --- --- --- T IMGT000082 TRAV12D-2*02 F V-REGION gDNA --- --- --- --- --- --- --- -c- --- --- ... ... ... ... ... ... --- --- --- --- X04330 TRAV12D-2*03 (F) V-REGION cDNA --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... --- --- --- --- T M15063 TRAV12D-2*04 (F) V-REGION cDNA --- --- --- --- --- --- --- -c- --- --- ... ... ... ... ... ... --- --- --- --- T M98569 TRAV12D-2*05 (F) V-REGION cDNA --- --- --- --- --- --- --- -c- --- --- ... ... ... ... ... ... --- --- --- --- _______________C 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 F W Y V Q H L N E A P K L L L K S F T D X04332 TRAV12D-2*01 F V-REGION gDNA ttc tgg tat gtg caa cat ctc aac gaa gcc cct aag cta ctt ttg aag agc ttc aca gac S AC005402 TRAV12D-2*02 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --c c-- --- --- -c- --- --- S AE007512 TRAV12D-2*02 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --c c-- --- --- -c- --- --- S AE008684 TRAV12D-2*02 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --c c-- --- --- -c- --- --- S IMGT000082 TRAV12D-2*02 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --c c-- --- --- -c- --- --- F X04330 TRAV12D-2*03 (F) V-REGION cDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --c --- --- --- --- --- S M15063 TRAV12D-2*04 (F) V-REGION cDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --c c-- --- --- -c- --- --- H S M98569 TRAV12D-2*05 (F) V-REGION cDNA --- --- c-- --- --- --- --- --- --- --- --- --- --- --c c-- --- --- -c- --- --- DR2-IMGT________________ 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 N K R P E H Q G F H A T X04332 TRAV12D-2*01 F V-REGION gDNA ... ... ... aac aag agg ccc gag cac ... ... ... ... ... caa ggg ttc cac gcc act T Y AC005402 TRAV12D-2*02 F V-REGION gDNA ... ... ... --- --- --- a-- --- --- ... ... ... ... ... --- --- --- t-- --- --- T Y AE007512 TRAV12D-2*02 F V-REGION gDNA ... ... ... --- --- --- a-- --- --- ... ... ... ... ... --- --- --- t-- --- --- T Y AE008684 TRAV12D-2*02 F V-REGION gDNA ... ... ... --- --- --- a-- --- --- ... ... ... ... ... --- --- --- t-- --- --- T Y IMGT000082 TRAV12D-2*02 F V-REGION gDNA ... ... ... --- --- --- a-- --- --- ... ... ... ... ... --- --- --- t-- --- --- X04330 TRAV12D-2*03 (F) V-REGION cDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- T Y M15063 TRAV12D-2*04 (F) V-REGION cDNA ... ... ... --- --- --- a-- --- --- ... ... ... ... ... --- --- --- t-- --- --- T Y M98569 TRAV12D-2*05 (F) V-REGION cDNA ... ... ... --- --- --- a-- --- --- ... ... ... ... ... --- --- --- t-- --- --- 80 81 82 83 84 84A 85 86 87 88 89 90 91 92 93 94 95 96 97 98 L H K S S S S F H L Q K S S A Q L S D X04332 TRAV12D-2*01 F V-REGION gDNA ctc cat aag agc agc ... agc tcc ttc cat ctg cag aag tcc tca gcg cag ctg tca gac V AC005402 TRAV12D-2*02 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- -t- --- --- --- --- V AE007512 TRAV12D-2*02 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- -t- --- --- --- --- V AE008684 TRAV12D-2*02 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- -t- --- --- --- --- V IMGT000082 TRAV12D-2*02 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- -t- --- --- --- --- X04330 TRAV12D-2*03 (F) V-REGION cDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- V M15063 TRAV12D-2*04 (F) V-REGION cDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- -t- --- --- --- --- V M98569 TRAV12D-2*05 (F) V-REGION cDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- -t- --- --- --- --- ___CDR3-IMGT____ 99 100 101 102 103 104 105 106 107 S A L Y Y C A L S X04332 TRAV12D-2*01 F V-REGION gDNA tct gcc ctg tac tac tgt gct ttg agt ga F AC005402 TRAV12D-2*02 F V-REGION gDNA --- --- --- --- -t- --- --- --- --- -- F AE007512 TRAV12D-2*02 F V-REGION gDNA --- --- --- --- -t- --- --- --- --- -- F AE008684 TRAV12D-2*02 F V-REGION gDNA --- --- --- --- -t- --- --- --- --- -- F IMGT000082 TRAV12D-2*02 F V-REGION gDNA --- --- --- --- -t- --- --- --- --- -- X04330 TRAV12D-2*03 (F) V-REGION cDNA --- --- --- --- --- --- --- --- --- a- F M15063 TRAV12D-2*04 (F) V-REGION cDNA --- --- --- --- -t- --- --- --- --- - F M98569 TRAV12D-2*05 (F) V-REGION cDNA --- --- --- --- -t- --- --- --- --c c
This alignment of allele is generated by IMGT/OutilAllele (Mehdi Yousfi, Chantal Ginestoux, Perrine Pégorier and Patrice Duroux).
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