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IMGT Repertoire (IG and TR)
Alignment of alleles: house mouse (Mus musculus) TRAV4-2
When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
- Dots indicate gaps according to the IMGT unique numbering.
- Blanks at the 5' and/or 3' end indicate partial sequences.
- Asterisk (*) in the sequence indicate a STOP-CODON.
- Letters in red correspond to amino acids which are polymorphic in the other alleles.
- Colours are according to Color menu for mutations, Color menu for sequence alignments and Color menu for splicing types.
- The nucleotide (s) in bold and colored in purple (splicing frame 1) or green (splicing frame 2) from the DONOR splice site are added at the beginning of the following exon in order to obtain and to complete the first CODON of the DOMAIN or REGION resulting from the splicing site. These first CODONs are in bold and colored in purple (splicing frame 1) or green (splicing frame 2)
- N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown in green
Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.
1 2 3 4 5 6 7 8 8A 9 10 11 12 13 14 15 16 17 18 19 G M P V E Q N P P A L S L Y E G A D S AC004407 TRAV4-2*01 F V-REGION gDNA gga atg ccg gtg gaa cag aat cct ... cca gcc ctg agt ctt tat gaa gga gct gac tct AE007512 TRAV4-2*01 F V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- AE008684 TRAV4-2*01 F V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- E AC122813 TRAV4-2*02 F V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --g --- E IMGT000082 TRAV4-2*02 F V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --g --- E M87848 TRAV4-2*02 F V-REGION cDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --g --- ___________________CDR1-IMGT____________________ 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 G L R C N F S T T M K S V AC004407 TRAV4-2*01 F V-REGION gDNA ggt ctg aga tgc aat ttt tct acc acc atg ... ... ... ... ... ... ... aaa agt gtc AE007512 TRAV4-2*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ... --- --- --- AE008684 TRAV4-2*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ... --- --- --- G AC122813 TRAV4-2*02 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ... --- g-- --- G IMGT000082 TRAV4-2*02 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ... --- g-- --- G M87848 TRAV4-2*02 F V-REGION cDNA --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ... --- g-- --- _______________C 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 Q W F Q Q N H R G R L I T L F Y L A Q AC004407 TRAV4-2*01 F V-REGION gDNA cag tgg ttt caa caa aat cac aga ggc aga ctt atc act ctg ttt tac ctg gct caa ... AE007512 TRAV4-2*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... AE008684 TRAV4-2*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... AC122813 TRAV4-2*02 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... IMGT000082 TRAV4-2*02 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... M87848 TRAV4-2*02 F V-REGION cDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ... DR2-IMGT________________ 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 G T K E N G R L K S T AC004407 TRAV4-2*01 F V-REGION gDNA ... ... ... ... gga aca aag gag aat ... ... ... ... ... gga agg tta aag tca aca AE007512 TRAV4-2*01 F V-REGION gDNA ... ... ... ... --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- AE008684 TRAV4-2*01 F V-REGION gDNA ... ... ... ... --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- AC122813 TRAV4-2*02 F V-REGION gDNA ... ... ... ... --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- IMGT000082 TRAV4-2*02 F V-REGION gDNA ... ... ... ... --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- M87848 TRAV4-2*02 F V-REGION cDNA ... ... ... ... --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 80 81 82 83 84 84A 85 86 87 88 89 90 91 92 93 94 95 96 97 98 F N S K E R Y S T L H I K D A Q L E D AC004407 TRAV4-2*01 F V-REGION gDNA ttc aat tct aag gag ... cgc tac agc acc ctg cac atc aag gat gca cag ctg gag gac AE007512 TRAV4-2*01 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- AE008684 TRAV4-2*01 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- AC122813 TRAV4-2*02 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- IMGT000082 TRAV4-2*02 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- M87848 TRAV4-2*02 F V-REGION cDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- ___CDR3-IMGT____ 99 100 101 102 103 104 105 106 107 S G T Y F C A A E AC004407 TRAV4-2*01 F V-REGION gDNA tca ggc act tac ttc tgt gct gct gag g AE007512 TRAV4-2*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- - AE008684 TRAV4-2*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- - V AC122813 TRAV4-2*02 F V-REGION gDNA --- --- --- --- --- --- --- -t- --- - V IMGT000082 TRAV4-2*02 F V-REGION gDNA --- --- --- --- --- --- --- -t- --- - V M87848 TRAV4-2*02 F V-REGION cDNA --- --- --- --- --- --- --- -t- ---
This alignment of allele is generated by IMGT/OutilAllele (Mehdi Yousfi, Chantal Ginestoux, Perrine Pégorier and Patrice Duroux).
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