IMGT Repertoire (IG and TR)

Alignment of alleles: house mouse (Mus musculus) TRAV5-4

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.

Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).

• Dots indicate gaps according to the IMGT unique numbering.
• Blanks at the 5' and/or 3' end indicate partial sequences.
• Asterisk (*) in the sequence indicate a STOP-CODON.
• Letters in red correspond to amino acids which are polymorphic in the other alleles.
• Colours are according to Color menu for mutations, Color menu for sequence alignments and Color menu for splicing types.
• The nucleotide (s) in bold and colored in purple (splicing frame 1) or green (splicing frame 2) from the DONOR splice site are added at the beginning of the following exon in order to obtain and to complete the first CODON of the DOMAIN or REGION resulting from the splicing site. These first CODONs are in bold and colored in purple (splicing frame 1) or green (splicing frame 2)
• N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown in green

Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.

                                                                                                                            
                                            
                                             1   2   3   4   5   6   7   8   8A  9   10  11  12  13  14  15  16  17  18  19 
                                             G   E   Q   V   E   Q   L   P       S   I   L   R   V   Q   E   R   S   S   A  
  AC003995   TRAV5-4*01 F V-REGION gDNA     ggc gag cag gtg gag cag ctt cct ... tcc atc ctg aga gtc cag gaa aga tcc agt gcc 

                                                                                                                            
  AE007512   TRAV5-4*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                            
  AE008685   TRAV5-4*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                             G              
  IMGT000082 TRAV5-4*02 F V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --g g-- --- --- --- 



                                                                        ___________________CDR1-IMGT____________________    
                                            
                                             20  21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39 
                                             S   I   N   C   T   Y   E   N   S   A                           S   N   Y   F  
  AC003995   TRAV5-4*01 F V-REGION gDNA     agc atc aac tgc act tat gag aac agt gcc ... ... ... ... ... ... tcc aac tac ttc 

                                                                                                                            
  AE007512   TRAV5-4*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... --- --- --- --- 

                                                                                                                            
  AE008685   TRAV5-4*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... --- --- --- --- 

                                                             S           D                                                  
  IMGT000082 TRAV5-4*02 F V-REGION gDNA     --- --- --- --- -g- --- --a g-- --- --- ... ... ... ... ... ... --- --- --- --- 



                                                                                                            _______________C
                                            
                                             40  41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59 
                                             P   W   Y   K   Q   E   P   G   E   N   P   K   L   I   I   D   I   R   S   N  
  AC003995   TRAV5-4*01 F V-REGION gDNA     cct tgg tat aag caa gaa cct gga gag aat cct aag ctc atc att gac att cgt tca aat 

                                                                                                                            
  AE007512   TRAV5-4*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                            
  AE008685   TRAV5-4*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                            
  IMGT000082 TRAV5-4*02 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 



                                            DR2-IMGT________________                                                        
                                            
                                             60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79 
                                                         M   E   R   K   Q   I                       Q   G   L   I   V   L  
  AC003995   TRAV5-4*01 F V-REGION gDNA     ... ... ... atg gaa aga aag cag atc ... ... ... ... ... caa gga ctc atc gtt tta 

                                                                                                                            
  AE007512   TRAV5-4*01 F V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                            
  AE008685   TRAV5-4*01 F V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                         E                  
  IMGT000082 TRAV5-4*02 F V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- -a- --- --- --- --- 



                                                                                                                            
                                            
                                             80  81  82  83  84 84A  85  86  87  88  89  90  91  92  93  94  95  96  97  98 
                                             L   D   K   K   A       K   R   F   S   L   H   I   T   D   T   Q   P   A   D  
  AC003995   TRAV5-4*01 F V-REGION gDNA     ctg gat aag aaa gcc ... aaa cgc ttc tcc ctg cac atc aca gac acc cag cct gca gac 

                                                                                                                            
  AE007512   TRAV5-4*01 F V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                            
  AE008685   TRAV5-4*01 F V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                     G      
  IMGT000082 TRAV5-4*02 F V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- -g- --- 



                                                                    ___CDR3-IMGT____
                                            
                                             99 100 101 102 103 104 105 106 107 
                                             S   A   M   Y   F   C   A   A   S  
  AC003995   TRAV5-4*01 F V-REGION gDNA     tca gcc atg tac ttc tgt gct gca agt g

                                                                                
  AE007512   TRAV5-4*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- -

                                                                                
  AE008685   TRAV5-4*01 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- -

                                                                                
  IMGT000082 TRAV5-4*02 F V-REGION gDNA     --- --- --- --- --- --- --- --- --- -

This alignment of allele is generated by IMGT/OutilAllele (Mehdi Yousfi, Chantal Ginestoux, Perrine Pégorier and Patrice Duroux).