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IMGT Repertoire (IG and TR)
Alignment of alleles: house mouse (Mus musculus) TRAV8D-2
When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
- Dots indicate gaps according to the IMGT unique numbering.
- Blanks at the 5' and/or 3' end indicate partial sequences.
- Asterisk (*) in the sequence indicate a STOP-CODON.
- Letters in red correspond to amino acids which are polymorphic in the other alleles.
- Colours are according to Color menu for mutations, Color menu for sequence alignments and Color menu for splicing types.
- The nucleotide (s) in bold and colored in purple (splicing frame 1) or green (splicing frame 2) from the DONOR splice site are added at the beginning of the following exon in order to obtain and to complete the first CODON of the DOMAIN or REGION resulting from the splicing site. These first CODONs are in bold and colored in purple (splicing frame 1) or green (splicing frame 2)
- N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown in green
Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.
1 2 3 4 5 6 7 8 8A 9 10 11 12 13 14 15 16 17 18 19 S Q W G E E N L Q A L S I Q E G E D V AC005855 TRAV8D-2*01 F V-REGION gDNA agc caa tgg gga gaa gag aat ctt ... cag gct ctg agc atc cag gag ggt gaa gat gtc AE007512 TRAV8D-2*01 F V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- AE008684 TRAV8D-2*01 F V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- U46581 TRAV8D-2*02 (F) V-REGION cDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- AC163653 TRAV8D-2*03 F V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- IMGT000082 TRAV8D-2*03 F V-REGION gDNA --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- ___________________CDR1-IMGT____________________ 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 T M N C S Y K T Y T T V V AC005855 TRAV8D-2*01 F V-REGION gDNA acc atg aac tgc agt tac aag act tac aca ... ... ... ... ... ... ... act gtt gtt AE007512 TRAV8D-2*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ... --- --- --- AE008684 TRAV8D-2*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ... --- --- --- U46581 TRAV8D-2*02 (F) V-REGION cDNA --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... ... --- --- --- AC163653 TRAV8D-2*03 F V-REGION gDNA --- --- --- --- --- --- --- --- --t --- ... ... ... ... ... ... ... --- --- --a IMGT000082 TRAV8D-2*03 F V-REGION gDNA --- --- --- --- --- --- --- --- --t --- ... ... ... ... ... ... ... --- --- --a _______________C 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 Q W Y R Q K S G K G P A L I I L I R S N AC005855 TRAV8D-2*01 F V-REGION gDNA cag tgg tac aga cag aag tca ggc aaa ggc cct gcc ctg ata atc tta ata cgt tca aat AE007512 TRAV8D-2*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- AE008684 TRAV8D-2*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- Q L U46581 TRAV8D-2*02 (F) V-REGION cDNA --- --- --- --- --- --- --- --- --- --- --- --- -a- c-- --- --- --- --- --- --- H D R AC163653 TRAV8D-2*03 F V-REGION gDNA --c --- --- --g --a g-c --- --- -g- --- --- --- --- --- --- --- --- --- --- --- H D R IMGT000082 TRAV8D-2*03 F V-REGION gDNA --c --- --- --g --a g-c --- --- -g- --- --- --- --- --- --- --- --- --- --- --- DR2-IMGT________________ 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 E R E K R S G R L R A T AC005855 TRAV8D-2*01 F V-REGION gDNA ... ... ... gag cga gag aag cgc agt ... ... ... ... ... gga aga ctc aga gcc acc AE007512 TRAV8D-2*01 F V-REGION gDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- AE008684 TRAV8D-2*01 F V-REGION gDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- U46581 TRAV8D-2*02 (F) V-REGION cDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- AC163653 TRAV8D-2*03 F V-REGION gDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --a --- --- --- IMGT000082 TRAV8D-2*03 F V-REGION gDNA ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --a --- --- --- 80 81 82 83 84 84A 85 86 87 88 89 90 91 92 93 94 95 96 97 98 L D T S S Q S S S L S I T G T L A T D AC005855 TRAV8D-2*01 F V-REGION gDNA ctt gac act tcc agc ... cag agc agc tcc ctg tcc atc act ggt act cta gct aca gac AE007512 TRAV8D-2*01 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- AE008684 TRAV8D-2*01 F V-REGION gDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- U46581 TRAV8D-2*02 (F) V-REGION cDNA --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- A A Q C E AC163653 TRAV8D-2*03 F V-REGION gDNA --- --- --c --- --- ... --a --t --- --t --- --- --- --- -c- g-- -ag tg- ga- --- A A Q C E IMGT000082 TRAV8D-2*03 F V-REGION gDNA --- --- --c --- --- ... --a --t --- --t --- --- --- --- -c- g-- -ag tg- ga- --- ___CDR3-IMGT____ 99 100 101 102 103 104 105 106 107 T A V Y F C A T D AC005855 TRAV8D-2*01 F V-REGION gDNA act gct gtg tac ttc tgt gct act gat g AE007512 TRAV8D-2*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- - AE008684 TRAV8D-2*01 F V-REGION gDNA --- --- --- --- --- --- --- --- --- - T U46581 TRAV8D-2*02 (F) V-REGION cDNA --- --- --- --- --- --- --- --a acc AC163653 TRAV8D-2*03 F V-REGION gDNA --- --- --- --- --- --- --- --a --- - IMGT000082 TRAV8D-2*03 F V-REGION gDNA --- --- --- --- --- --- --- --a --- -
This alignment of allele is generated by IMGT/OutilAllele (Mehdi Yousfi, Chantal Ginestoux, Perrine Pégorier and Patrice Duroux).
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