Here you are: IMGT Web resources > IMGT Repertoire (IG and TR) > 2. Proteins and alleles

Only the *01 allele of each functional, ORF and in-frame pseudogenes C-REGION is shown.

Letters in red correspond to amino acids which are polymorphic in the other alleles.
For C-REGIONs, letters in bold correspond to additional positions in the IMGT unique numbering.
For C-REGIONs, letters between parentheses correspond to amino acids resulting from the splicing.

Functionality is shown between:
- parentheses, (F) and (P), when the accession number refers to rearranged genomic DNA or cDNA and the corresponding germline gene has not yet been isolated.
- brackets, [F] and [P], when the accession number refers to genomic DNA, but not known as being germline or rearranged.

N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown is green (site is underlined in CHS and in pages edited before 14/10/2009).

The IGHC protein display numbering is according to the IMGT unique numbering for C-DOMAIN and C-LIKE-DOMAIN.

                    A        AB     B           BC         C     CD      D          DE           E      EF   F          FG            G           
                 (1-15)          (16-26)     (27-38)    (39-45)       (77-84)                 (85-96)     (97-104)   (105-117)    (118-128)   
             ——————————————>   ——————————> ———————————> ——————>       ———————>              ———————————>  ———————> ————————————> ——————————>
C GenesAccNumDomain
             1        10  15   16  20 2326 27        38 3941 45       77 80 84              85  89    96  97   104 105       117 118121     
     87654321|........|....|123|...|..|..| |..........| |.|...|1234567|..|...|12345677654321|...|......|12|......| |...........| |..|.......
CH1
SalsalIGHD1AF278717CH1 F 
     ..(V)QRVIPPNITLYPLWEELEG..GSKVGLLCILS EFYP....DKLS VEWLLDDKTVTTY.PVQRKLQSVEGEE.....KTFSLNSQLELDQSQW..TQGSEVTC KAIHNA.AQGPHP GTTVSRTISICS
SalsalIGHD2AF141605CH1 F 
     ..(V)QRVIPPNITLYPLWEELEG..GSKVGLLCILS GFYP....DKLS VEWLLDDKTATTS.PVQRKLQSVEGEE.....KTFSLNSQLELDQGQW..TQGSEVTC KATHNA.AQGPPP GTTVSRTISICS
OncmykIGHDAY872256CH1 F 
     ..(V)QRVIPPNITLYPLWEELEV..GSKVGILCILS GFYP....DKLS VEWLLDDKTVTTS.PVQQKLQSVEGED.....KIFSLNSQLELDQSQW..TQGSEVTC KATHNA.AQGPPT GTPVSRTTSICS
IctpunIGHD1DQ400445CH1 F 
     ......(A)QRVTEPNITMSTNTM..DNNVNLLCWLD GFSP....KKIS VEWYKGNTLHTKK.TTMKIFESLNNGE.....KTFGALSQLSINAEQW..NEGTEFTC KATHI....SKIF SQTWSKCK
IctpunIGHD2AF363449CH1 F 
     ......(X)QHVTEPNITMSTNTM..DNNVNLLCWLD GFSP....KKIS VAWYKGNMLHTEK.TTMKIFENLNNGE.....RTFGALSQLSINAQQW..NEGTEFTC KATHN....SKIF SQTWSKCK
GadmorIGHD AF155199CH1(F)#c
     ..(V)ERVISPNITLYPVWTGQSW..ASELSLVCTLS GFYP....DKVS VEWLLDGRVPETS.PVQNKLQSVAEVG.....KTFTLNSKIQLKIEEW..KKGPNVQC KSKYG...HGKEA TRNISICA
GadmorIGHD AF155199CH1D(F)#c
     ..(V)EQVIPPNITLYPVWTGQSW..ASELSLVCTLS GFYP....DKVS VEWLLDGRVPETS.PVQNKLQSVEEGG.....KTFTLNSKIQLKIEVW..KKGPNVQC KSKYG...HGKEE TRNISICD
ParoliIGHD AB052658CH1(F)#c
     ..(K)SRVVSPNITLYPVWEGEFG..VSPVRLICTLS GFFP....DQLQ VEWHKDNHLLHIT.PTQTKLQSMQGEE.....KTFSLISDIEA..VNW..KSNSTFTC KAQHN...NDKKF TKTVNFVQICS
DanrerIGHD BX510335CH1ORF
     .........(X)TKPRIALLSRED..GDRIMLECHLK DYYP....EEFS VQWLYNGQPVS...GTNRMLQNKEVE......KTFTYISQLNISYS....HDYKNYTC YANHN....SKVY QQDYNRCT
HiphipIGHD AY077847CH1(F)#c
     ..(V)VQVFEPNITLHPVWEGEFG..ASPVRLICTLS GFTP....NNLK VKWQKDNIPLTIT.QTETKLQPLQGVE.....KTFSQSSNIEPAKKEW..ESGSTFSC KAQHN....KREF TKTVNICQVYS
CH2
SalsalIGHD1AF278717CH2 F 
     .(A)FPSSTPSLHLETPRFRTVMT..QTEVTATCVVH SAY......DAK VSWHLDGKDPTS..RTPVNQASSTT.........QSISSNLTLPSSQW..KTLNTITC RAEHRC.FNPTQR TSNVN
SalsalIGHD1AF278717CH2D F 
     .(A)FPSSTPSLHLETPRFRTVMT..QTEVTATCVVH SAY......DAK VSWLLDGKDPTS..RTPVNQASSTT.........QSISSNLTLPSSQW..KTLNTITC RAEHRC.FNPTQR TSNVN
SalsalIGHD2AF141605CH2 F 
     .(A)FPSSTPSIHLETPRFRTVMT..QTEVTATCVVH SAY......DAK VAWLLDGKDPTS..RTPVNQASSTT.........QSISSNLTLPSSQW..KTLNTITC RAEHRC.FNRTQR TSNVK
SalsalIGHD2AF141605CH2D F 
     .(A)FPSSTPSIHLETPRFRTVMT..QTEVTATCVVH SAY......DTK VSWLLDGKDPTS..RTPVNQASSTT.........QSISSNLTLPSSQW..KTLNTITC RAEHRC.FNRTQR TSNVK
OncmykIGHDAY872256CH2 F 
     .(A)FPSSTPSIHLETPTFRTVMT..QTEVTATCVVH SAY......DSN VSWLLDGKDPTS..RTPVNQASRTT.........QSISSNLTLPSSQW..KTLNTITC RAEHRC.FNSTEK TSNVK
OncmykIGHDAY872256CH2D F 
     .(A)FPSSTPSLHLETPRFRTVMT..QTEVTATCIVH SAY......DAK VSWLLDGKDPTS..RTPVNQASSTT.........QSISSNLTLPSSQW..KTLNTITC RAEHRC.FNSTEK TRNVK
OncmykIGHDAY872257CH2D F 
(1)  .(A)FPSSTPSLHLETPRFRTVMT..QTEVTATCVVH SAY......DAK VSWLLDGKDPTS..RTPVNQASSTT.........QSISSNLTLPSSQW..KTLNTITC RAEHRC.FNSTEK TRNVK
IctpunIGHD1DQ400445CH2 F 
     .(A)EPTSKPLIRLEKPGLMSVLT..DSEVTASCVVE TVH......NTK VSWFVDGKEKTD..RVTLKTLDG............RTVSNLTISTNDW..KNWQTIKC TAAHLC.FGTVEK TINIL
IctpunIGHD1DQ400445CH2D F 
     .(A)HSTVKPLIRLEKPGLMSVLT..DSEVTASCVVE TVH......NTK VSWFVDGKEKTD..RVTLKTLDG............RTVSNLTISTNDW..KNWQTIKC TAAHLC.FGTVEK TINIL
IctpunIGHD1DQ400445CH2D2 F 
     .(A)HSTVKPLIRLEKPGLMSVLT..DSEVTASCVVE TVL......NSR VSWFVDGREKTN..RVTLKTLDG............RTVSNLTISTDEW..KNWQTIKC TAKHPC.FDTVEK TINIL
IctpunIGHD2AF363449CH2 F 
     .(A)EPTSKPLIRLEKPGLMSVLT..DSEVTASCVVE TVH......NTK VSWFVDGREKTD..RVTLKTLDG............RTVSNLTISTNEW..KNWQTIKC TAAHLC.FGTVEK TINIL
IctpunIGHD2AF363449CH2D F 
     .(A)HSTVKPLIRLEKPGLMSVLT..DSEVTASCVVE TVL......NSR VSWFVDGGEKTN..RVTLKTLDG............RTVSNLTISTDEW..KNWQTIKC TAKHPC.FDTVEK TINIL
GadmorIGHD AF155199CH2(F)#c
     ..(I)YSYPPSVHLTTPSFKTVIEA.GSDVTAACVVH TAF......DVN VTWHLDGKALTT..PNHVTKVKEG..........ALTRSNLTVSSSQW..KKLNSITC RAEHCF..TTVEK NMTVA
GadmorIGHD AF155199CH2D(F)#c
     ..(I)YSYPPSVHLTTPSFKTVIEA.GSDVTAACVVH TAF......DVN VTWHLDGKALTT..PNHVTEVKEG..........ALTRSNLTVSSSHW..KKLNSITC RAEHCF..TTVEK NMSVA
ParoliIGHD AB052658CH2(F)#c
     ....(S)AAPSIDVEIPSFRTVMT..ESAVTAKCSVN NRF......GAK VTWLMDGKAESK..YIVTSNANQT...........HTISEVAVPPSQW..KQLKSITC KADHQC..FSTQR TVNVA
DanrerIGHD BX510335CH2DORF
     (A)HCFIKPSIQIKTNPLRDIIK...TGNVTLSCVVK APD......ITI VSWLVDGQSEPTT.TPHKDLSNN.............TVSYLTVSTKDW...LKKTIVC IAQHPC.FSNESR ENQAGK
DanrerIGHD BX510335CH2D2ORF
     (A)HCFIKPSIQIKTNPLRDIIK...TGNVTLSCVVK APD......ITI VSWLVDGQSEPTT.TPHKDLSNN.............TVSYLTVSTKDW...LKKTIVC FAQHPC.FSNESR ENQAGK
DanrerIGHD BX510335CH2D3ORF
     (A)HCLIKPSIQIKTNPLKDIIK...TGNVTLSCVVK APE......YTV VSWLVDGQSEPTT.TPHKDLSNN.............TVSYLTVSTKDW...LKKTIVC FAQHPC.FSNESH ENQAGK
HiphipIGHD AY077847CH2(F)#c
     ....(S)AAASIDVEIPSFRTVMT..ESAVTATCSVH TLF......NAK LTWLMDGGDAPS..NTVTQKSNTT...........HIIRDLSVPSSQW..KQLKAITC KADHKC.LSSTQR TVNVA
HiphipIGHD AY077848CH2D(F)#c
     ....(S)AAASIDVEIPSFRTVMT..ESAVTATCSVH TLF......NAK LTWLMDGGDAPS..NTVTQKSNTT...........HIISDLSVPSSQW..KQLKSITC KADHKC.LSSTQR TVNVA
CH3
SalsalIGHD1AF278717CH3 F 
     (G)PAVSSTPTVLIRRSLPDLLD...GDSAVLECAIT QLS......SSD LYVTFQANGVDFP.EKQYVDLPASKD.......PHSLTRRFSIPTSHW..KKENTFTC KVNQGY..SNSWV SNSTGTLF
SalsalIGHD1AF278717CH3D F 
     (G)PAVTSTPTVLIRRSLPDLLD...GDSAVLECAIT QLS......SSD LYVTFQANGVDFP.EKQYVDLPASKD.......PHSLTRRFSIPTSHW..KKENTFTC KVNQGY..SNSWV SNSTGTLF
SalsalIGHD2AF141605CH3 F 
     (G)PAVSSTPTVLIRRSLPDLLD...GDSAVLECAIT QLS......SSD IYVTFQANGVDFP.EKQYVDLPASKD.......HHSLTRRFSIPTSHW..KKDNTFTC KVNQGY..SNSWV SNSTGTLF
SalsalIGHD2AF141605CH3D F 
     (G)PAVSSTPTVLIRRSLPDLLD...GDSAVLECAIT QLS......SSD LYVTFQANGVDFP.EKQYVDLPASKD.......HHSLTRRFSIPTSHW..KKDNTFTC KVNQGY..SNSWV SNSTGTLF
OncmykIGHDAY872256CH3 F 
     (G)PAVSSTTTVLIRRSLPELLK...GDSAVLECAIT QLS......SSD LYVTFQANGVDFP.EKQYVDLPASNG.......PHSLTKRFSIPKSHW..KTDNTFTC KVNQGY..SNSWV SSSKIKLF
OncmykIGHDAY872257CH3D F 
     (G)PAVSSTTTVLIRRSLPELLK...GDSAVLECAIT QLS......SSD LYVTFQANGVDFP.EKQYVDLPASNG.......PHSLTKRFSIPKSHW..KTDNTFTC KVNQGY..SNSWV SSSKIKLF
IctpunIGHD1DQ400445CH3 F 
     .(E)PVQKTPTVVIRRNLADILK...GDSAVLECAAR DLP......SGE LSVILQANGIRVF.EPQYVDLPKGV.........DTLTARFTVSTTQR..NKNQRFTC QIQQSR..SKQWT SNSIENLF
IctpunIGHD1DQ400445CH3D F 
     .(E)PVQKTPTVVIRRNLADILK...GDSAVLECAAR DLP......SGE LSVILQANGIRVF.EPQYVDLPKGV.........DTLTARFTVSTTQR..NKNQQFTC QIQQSR..SKQWT SNSIENLF
IctpunIGHD1DQ400445CH3D2 F 
     .(E)PVQKTPTVVIRRNLADILK...GDSAVLECAAR DLP......SGE LLVILQANGRRVL.EPQYVDLPKGV.........DTLTARFTVSTTQR..NKNQRFTC QIQQSR..SKQWT SNSIENLF
IctpunIGHD2AF363449CH3 F 
     .(E)PVQKTPTVVIRRNLADILK...GDSAVLECAAR DLP......SGE LSVILHANGIRVL.EPQYVDLPKGV.........DTLTARFTVPTTHR..NKNQRFTC QIQQSR..SKQWT SNSIENLF
IctpunIGHD2AF363449CH3D F 
     .(E)PVQKTPTVVIRRNLADILK...GDSAVLECAAR DLP......SGE LLVILQANGIRVL.EPQYVDLPKGV.........DTLTARFTVPTTHR..NKNQRFTC QIQQSR..SKQWT SNSIENLF
ParoliIGHD AB052658CH3(F)#c
     .(G)PAVTNASVEIKRSFPDLLK...GQSAVLECDIT KLS......SSD LYVTFQANDKDIS.EKQYVVLPEAPD.......PQSITRRFSIPSSYW..KKDTTFSC KVHQGF..SPSVK SKSTGNIF
DanrerIGHD BX510335CH3ORF
     .(K)DVKKDPEVEIRRSFMKSSAP..VSDAVLECVVG DLS......PGE VCITFQANNVDIS.DLDCVDSAPSNN.......SWSLIRNFTIPSSNQ..TTENNFTC KVHSA...FKEWT SKPTGHIF
DanrerIGHD BX510335CH3DORF
     .(K)DVKKDPEVEIRRSFMKSSAP..VSDAVLECVVG DLS......PGE VCITFQANNVDIS.DLDCVDSAPSNN.......SWSLIRNFTIPSSNQ..TTENNFTC KVHRA...FKEWT SKPTGHIF
DanrerIGHD BX510335CH3D2ORF
     .(K)DVKKDPEVEIRRSFMKSSAP..VSDAVLECVVG DLS......PGE VCITFQANNVDIS.DLDCVDSAPSNN.......SWSLIRNFTIPSSNQ..TTENNFTC KVHRA...FKEWT SKPTGHIF
DanrerIGHD BX510335CH3D3ORF
     .(K)NVKKDPEVEIRRSFMKSSAP..VGGAVLECVVG DLS......PGE VCITFQANNVDIS.DLDCVDSAPSNN.......SWSLIRNFTIPSSNQ..TTENNFTC KVHSA...FKEWT SKPTGHIF
HiphipIGHD AY077847CH3(F)#c
     .(G)PAVTVPSVEIKRSLRDLLK...GQSAVLECDIT NLS......SSD LYVTFQANDEDIS.DRQFVDLPVAPG.......LHSITRHFSIPPSHW..RKDTNFTC KVHQGF..SSNFK SESTGNIF
HiphipIGHD AY077848CH3D(F)#c
     .(G)PAVTVPSVEIKRSLRDLLK...GQSAVLECDIT NLS......SSD LYVTFQANDEDIS.DRQFVDLPVAPG.......LHSITRHFSIPPSHW..RKDTNFTC KVHQGF..SSNFK SESTGNIF
CH4
SalsalIGHD1AF278717CH4 F 
     .....(G)ELSMELLLVPNEEMSG..SGTQKLMCSGR GFN.......PQ IRWLSGS.......KQRSAADNERGMRE...DGHVAVTSHITVTQQEW..NEGKDFIC EVID......KDL QKTVRKSTSLCT
SalsalIGHD1AF278717CH4D F 
     .....(G)ELSMELLLVPNEEMSG..SGTQKLMCSGR GFN.......PQ IKWLSVSAAAYEIRSKQRSAADNERRMR..EDGHVAVTSHITVTQQEW..NQGKDFTC EVIDKY..LQKED LQKVRMSINICA
SalsalIGHD2AF141605CH4 F 
     .....(G)EPSMELLLVPNEELSG..SGTQKLMCSGR GFN.......PQ IKWLSGS.......NQRSAADNERRMRE...DGHVAVTSHITVTQQEW..NEGKDFIC EVID......KDL QKTVRKSTSLCT
SalsalIGHD2AF141605CH4D F 
     .....(G)EPSMELLLVPNEELSG..SGTQKLMCSGR GFN.......PQ IKWLSVSAAAYEIR............MG..EDERVAVTSHITVTQQEW..NQGKNFTC EVIDKY..LQKED LQKVRKSINICA
OncmykIGHDAY872256CH4 F 
     .....(G)ELSMELLLVPSEESSG..SGTQKLMCSGW GFN.......PK IKWLSGS.......EQKSAADNEIRMGE...DGHVALTSHITVTQQEW..NEGKDFIC EVDD......KDL QKTVRKSTSLCT
OncmykIGHDAY872257CH4D F 
     .....(G)ELSMELLLVPSEESSG..SGTQKLMCSGW GFN.......PK IKWLSGS........EQKSAADNEMRMG..EDGHVALTSHITVTQQEW..NEGKDFIC EVDD......KDL QKTVRKSTSLCT
IctpunIGHD1DQ400445CH4 F 
     .....(G)DPSVELSAVSNTDNSG..SITQKLICSGT GFN.......PQ IKWLHKS.......VPNALTEVMMQGD.....GRVKVSSEILVQQQEW....NIDCVC EVSD......QDN PKHVQKSTRVCA
IctpunIGHD1DQ400445CH4D F 
     .....(G)DPSVELSAVSNTDNSG..SITQKLICSGT GFN.......PQ IKWLHKS.......VPNALTEVMMQGD.....GRVKVSSEILVQQQEW....NIDCVC EVSD......QDN PKHVQKSTRVCA
IctpunIGHD1DQ400445CH4D2 F 
    ......(G)DPSVELLVISSVDKSA..SATQKLLCAAT GLN.......PK IKWLPES.......VVNALNGLSKVTVD..SDGRVKVSSEISVSQQQW..NNRVTFTC RVSD......QDT LKPVEKSTSICA
IctpunIGHD2AF363449CH4 F 
     .....(G)DPSVELSAVSNTDNSG..SITQKLICSGT GFN.......PQ IKWLHKS.......VPNALTEVMMQGD.....GRVKVSSEILVQQQEW....NIDCVC EVSD......QDN PKHVQKSTRVCA
IctpunIGHD2AF363449CH4D F 
     .....(G)DPSVELLVISSVDKSA..SATQKLLCAAT GLN.......PK IKWLPES.......VVNALNGLSKVTVD..SDGRVKVSSEISVPQQQW..NNRVTFTC RVSD......QDP LKPVEKSTSICA
ParoliIGHD AB052658CH4(F)#c
     .....(V)DPSVELLLFPNE.LSG....PQRLLCSGR GFN.......PK IQWLSVS.......NKLPSNNDVTMGA....DGRVVVTSQLQIPQTEW..ETGKVYSC EVSD......TSL SKTVSKNISLCS
DanrerIGHD BX510335CH4ORF
     .....(D)NASSELVVGPKVVQSS..SEYQKLLCSAT GFY.......PK IEWLPQS.......SVKASNSTITLMQ....DGHVKVYSEILVPQDEW..NKGVNFTC LVTD......GTN KETVEKNTSICS
DanrerIGHD BX510335CH4DORF
     .....(D)NASSELVVGPKVVQSS..SEYQKLLCSAT GFY.......PK IQWLPQS.......SVKASNSTVTLMQ....DGHVKVYSEILVPQDEW..NKGVNYTC LVTD......GTN KETVEKNTSICS
DanrerIGHD BX510335CH4D2ORF
     .....(D)NASSELVVGPKVVQSS..SEYQKLLCSAT GFY.......PK IQWLPQS.......SVKASNSTVTLMQ....DGHVKVYSEILVPQDEW..NKGVNYTC LVTD......GTN KETVEKNTSICS
DanrerIGHD BX510335CH4D3ORF
     .....(D)NASSELVVGPKVVQSS..SEYQKLLCSAT GFY.......PK IQWLPQS.......SVKASNSTVTLMQ....DGHVKVYSEILVPQDEW..NKGVNYTC LVTD......GTN REPVEKNTSICS
HiphipIGHD AY077848CH4(F)#c
     .....(V)DPSVEPLLVPSEE.SG....PQRLLCSGW GFN.......PQ IQWLSES.......KQRSSNNDVTMGA....DGRVAVTSPRNIPQTEW..KTGKVFTC QVSD......TSL NKTVHKNVSLCSVSS
HiphipIGHD AY077848CH4D(F)#c
     .....(V)DPSVELLLVPSEE.SG....PQRVLCSGW GFN.......PQ IQWLSES.......KQRSSNNDVTMGA....DGRVAVTSPRNIPQTEW..KTGKVFTC QVSD......TSL NKTVRKNVSLCS
CH5
SalsalIGHD1AF278717CH5 F 
    (V)TPISSQKVAVYLQGPTLQELRT..DGQVPVTCLLV GPSL....GDFS VSWKVDGFVASQ..GGVTRAPKDHSN......GTQTEQIMFNVSARDW..HAHKLVSC EVKHRC..SSQAQ VEHITKCR
SalsalIGHD2AF141605CH5 F 
    (V)TPISSQKVGVYLQGPTLQELRT..GGQVPVTCLLV GPRL....GDFS VSWKVDGFVASQ..GGVTRAPKDHSN......GTQTEQIMFNVSARDW..HAHKLVSC EVKHRC..SSQAQ VEHITKCR
IctpunIGHD1DQ400445CH5 F 
    (V)TPDFAQKAQVYLLAPSISDMRA..NH.VSVTCLLL GHRL....NDFS IVWKIGKNNTSQ..GVTTQPLRVHSN......GTESVRSVLKVPAAKW..NAYKTVSC EVTHLC..STTKM EHTISKTR
IctpunIGHD2AF363449CH5 F 
    (V)TPDFAQKAQVYLLAPSISDMRA..NHHVSVTCLLL GHRL....NDFS IVWKIGKDITSQ..GVTTQPLRVHSN......GTESVRSVLKVPAAKW..NAYKTVSC EVTHLC..GTKKM EHTISKTR
ParoliIGHD AB052658CH5(F)#c
    (V)TPASSQIVGVYVQGPPLEEFKK..KEQVTITCLLV GSRL....NEFS ITWKVAGKKSSL..NFKKEPPVSHSN......GTESLMSVFSPSAEDW..HAHKQVSC EAKHLC..SSQGY EGHTSKSR
DanrerIGHD BX510335CH5ORF
    (V)IAPSSQQADVFLLGPPLSFASS....DLNLTCIVI GQNV....EYFI FQWKVNGNNS....DGIDQAPVQHLN......GTQSKVNLLKVSVNTW..NSHALITC EVKHLC..SVDTQ KQRILKTR
HiphipIGHD AY077849CH5(F)#c
    (V)TPASSQIVGVFVQGPPLEEFQN..KGQVTITCLLV GSRL....NDFF ITWKVDGDKSSL..FHKEPPVR.HSN......GTETLRSVFNVSAEDW..HAHKQVSC GAKHLC..SSQGY EGHTSKSR
CH6
SalsalIGHD1AF278717CH6 F 
     ...(D)PKPPSIKIVRPSVSDLWG..SNNATLLCLVS GFFP....SDVI VNWEKAGSRLPFS.RYSSIPSVLYAGS.....STYSMNSRLIVPRSEW..DHNSNYSC AVRHES..SERPI TSTIENVF
SalsalIGHD2AF141605CH6 F 
     ...(D)PKPPSIKIVRPSDSDLWG..SNNATLLCLVS GFFP....SDVI VNWEKAGSRLPFS.RYSSIPSFLYAGS.....STYSMNSRLIVPRSEW..DQNSNYSC AVRHES..SERPI THTIENVF
IctpunIGHD1DQ400445CH6 F 
     ...(D)RKSPTVRILSPSDDDLSG..VRNTNLLCLVD GFRP....ADIS VHWELNGRQLDAS.KFINSPVGNASAL.....GDYSMHSVLILPASK...RENSTFSC VVSHES..SEKPI RNSINNVY
IctpunIGHD2AF363450CH6 F 
     ...(D)RKSPTVRILSPSDDDLSG..VRNTYLLCLVD GFRP....ADIS VHWELNGSRLDAS.QFMNSPVGIRSAW.....SDYSMHSALILPASK...REDGTFSC VVSHES..SEKPI RNSINNIY
ParoliIGHD AB052658CH6(F)#c
     ...(V)LHQPTVKIIQPTASELSA..PDDLPLICLVS GFYP....PNVI VYWEGSGQRLPST.RYTNSDVWTYTGN.....STYSMSSRLNISKTE...DKSSTYSC FVRHES..SEKPF KNTIKNVF
DanrerIGHD BX510335CH6ORF
     ...(D)PKQPTVRILRPSDSDLSG..GKISSLVCFIS DFFP....SDIL VEWKLNGKQLSRS.QFSNSPLVALSS......GGFSMHSALILPGEQ...QKDGIYSC EVSHES..SQKPI NATLENLY
HiphipIGHD AY077849CH6(F)#c
     ...(V)FHQPTVKIIQPTASELSA..SDDLPLICLVS GFYP....SNVI VYWEGSGQRLPST.RYTNSAEWTYTGS.....GTYSMSSRLNISKTE...DKSSTYSC FVRHES..SETPF KSTIKNVF
CH7
SalsalIGHD1AF278717CH7 F 
     .......(G)SVTPSAPTATLL....QGPSELVCLVL GFSP....SDIN ITWLLDNVTEL...WNNNTSTTYRAPG.....GKFGIRSHLSLAHQDW..TPGAVYTC RVTHT....TQTL ALNISKP
SalsalIGHD2AF141605CH7 F 
     .......(G)SVTPSAPTATLL....QGPSELVCLVL GFSP....SDIN ITWLLDNVTEL...WNNNTSTTYRAPG.....GKFGIRSHLSLAHQDW..TPGAVYTC RVTHT....TQTL ALNISKP
OncmykIGHDAY872257CH7 F 
     .......(G)SVTPSAPTATLL....QGPSELVCLVL GFSP....SDIN ITWLLDNVTEL...WNNNTSTPYRAPG.....GKFGIRSHLSLARQDL..TPGAVYTC RVTHT....TQTL ALNISKP
IctpunIGHD1DQ400445CH7 F 
     .......(A)SVTENAPSVELL....QGQNKLVCLVY GYSP....SAIN ITWLLNSVSVQ...HDNSTKSSAKRPD.....GKFSIKSHLKVQASEW..APGDTYTC QVKHI....TGIV TRDISKK
IctpunIGHD2AF363450CH7 F 
     .......(A)SVTENAPSVELL....QGQNKLVCLVY GYSP....SAIN ITWLLNSVSVQ...HDDSTNSSAKRPD.....GKFSIKSHLKVQASEW..APGDTYTC HVEHI....TGIV TRDISKK
GadmorIGHD AF155199CH7(F)#c
     .......(G)SLSHSQPSALLL....QGPNELVCLAY GFSP....ASIN ITWLLDGTTQL...RSYNTSEPHRGPK.....GKFSIQSRLPLSPHEW..LPGQMYTC RVNHC....NGNI ALNMSKP
ParoliIGHD AB052658CH7(F)#c
     .......(A)TVTHTKPSATLL....QGTNELVCLVF GFSP....ASIN ITWFLDESTQL...LDYNTSKPHKSQN.....GKFSVRSHLRLPKGNW..LPGATVTC RVSHA....TTNL SLNISNL
DanrerIGHD BX510335CH7ORF
     .......(A)SLHHSAPSAELL....QGADGLMCLVS GFSP....SSIN ITWFMGMTEM....SEQNKTKLAKYPD.....GKFLIQSHLPLKPSDW..APGEVYTC RVTHV....TGTQ WFNISKNS
HiphipIGHD AY077849CH7(F)#c
     .......(A)TVTLSEPSATLL....QGTNELVCLVF GFSP....ASIN ITWFLDESVPL...LDYNTSEPHESQN.....GKFSVQSHLRPPKGNW..LPGAIVTC RVSHA....NTTL SLNISKP
CHS
     130       140      150
     .|.........|.........|.
IctpunIGHD2AF363450CHS F 
     FTEETIYFDENKYEQLLTAPSRV
H
GadmorIGHD AF155199H(F)#c
     DSRWTTEI
M
                              M1                           M2
SalsalIGHD1AF278717M F 
     (E)LLGVEGVFFDENRSDPILADTAEENWNMACIFLVLFLISLLYSITVTLVK TK
SalsalIGHD2AF141605M F 
     (V)LLGVEGVFFDENRSDPILADTAEENWNMACIFLVLFLISLLYSITVTLVK TK
OncmykIGHDAY872257M F 
     (E)LLEVEGVFFDENRSEPILADTAEENWNMACIFLVLFLISLLYSFTVTLVK TK
IctpunIGHD1DQ400445M F 
      (E)FTEETIYFDENTSETSTLDQAEETWNMACAFIILFVISLLYGCSVTLVK VIAA
GadmorIGHD AF155199M(F)#c
      (E)ILEESVLFDENKQVFVQDMGEDN.WMMTITFLLLFFVSLFYGILVTVIK TK
ParoliIGHD AB052658M(F)#c
      (D)NLEHCTFFDELLNADVNQDIGVESWYMALTFLLLFLISVIFGVSATMIK TK
DanrerIGHD BX510335MORF
      (V)ISEEAIFMNEIKPEFIPQDTVGEVWNMACAFLILFLLALVYGCTVTLVK VKSE
HiphipIGHD AY077849M(F)#c
      (D)NLERCTFFNEIFNADVNQDIGVESWYMALTFMLLFFISVIFGVLAIMIK TK
            CONNECTING_REGION   | TRANSMEMBRANE-REGION  | CYTOPLASMIC-REGION 
IMGT notes:

 #c: rearranged cDNA
(1): Functional but the C-REGION contains repetitive regions

Gadmor: Gadus morhua (Atlantic cod)
Hiphip: Hippoglossus hippoglossus (Atlantic halibut)
Ictpun: Ictalurus punctatus (Channel catfish)
Oncmyk: Oncorhynchus mykiss (Rainbow trout)
Paroli: Paralichthys olivaceus (Japanese flounder)
Salsal: Salmo salar (Atlantic salmon)