Motifs of the V-GENE PROMOTERs: Human IGKV

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For complete organization of the human IGKV PROMOTERs, click here

IGKV
subgroup
IGKV
gene name
Fct IGKV
allele name
Accession
number
PENTADECAMER
(1) (2)
Number of
nucleotides
between
PENTADECAMER
and DECAMER
DECAMER/
OCTAMER (1) (3)
Number of
nucleotides
between
DECAMER
and TATA_BOX
TATA_BOX Number of
nucleotides
between
TATA_BOX
and ATG
1 IGKV1-5 F IGKV1-5*01 Z00001 tgcagctgtgcccag 17 tcatttgcat 32 ttattaata 46
F IGKV1-5*01 J00245 tgcccag. . . . . . . . 17 tcatttgcat 32 ttattaata 46
F IGKV1-5*02 M23851 tgcagctgtgcccag 17 tcatttgcat 31 ttattaata 46
IGKV1-6 F IGKV1-6*01 M64858 tgcagctgtgcccag 17 tcatttgcat 32 ttattaaca 46
IGKV1-8 F IGKV1-8*01 Z00014 tgcagctgtgcccag 17 tca. . . . . . . 18 ttattaata 52
IGKV1-9 F IGKV1-9*01 Z00013 cgcagctgtatccag 17 cgatttgctt 32 ttcttaata 45
IGKV1-12 F IGKV1-12*01 V01577 tgcagctgcgcccag 17 tcatttgcat 32 ttattaaca 46
F IGKV1-12*01 K02094 tgcagctgcgcccag 17 tcatttgcat 32 ttattaaca 48
IGKV1-12/IGKV1D-12 F IGKV1-12*02/IGKV1D-12*02 V01576 tgcagctgtgcccag 17 tcatttgcat 31 ttcttaata 46
IGKV1-13 P IGKV1-13*01 Z00010 tgcagctgtgcccag 16 tcatttgcat 32 ttcttaata 46
IGKV1-13/1D-13 F IGKV1-13*02/IGKV1D-13*02 Z00006 tgcagctgtgcccag 17 tcatttgcat 32 ttcttaata 46
IGKV1-16 F IGKV1-16*01 J00248 tgcagctgtgcccag 17 tcatttgcat 32 ttattaata 46
IGKV1-17 F IGKV1-17*01 X72808 tgcagctgcgcccag 17 tcatttgcat 32 ttattaata 46
IGKV1-22 P   X71885 tgcagctgtgcccag 17 tgatttgcat 32 ttcttaata 46
IGKV1-27 F IGKV1-27*01 X63398 tgcagtgttattgag 23 agatttgcat 33 ttatcaata 46
IGKV1-32 P   J00250 tgcaggtaaagtcat 14 aaattttcat 32 ttgtacaca 46
P   X71883 tgcaggtaaagtcat 14 aaattttcat 32 ttgtacaca 46
IGKV1-33 F IGKV1-33*01 M64856 tgcagctgtgcccag 17 tgatttgcat 32 ttattaata 46
F IGKV1-33*01 M64857 tgcagctgtgcccag 17 tgatttgcat 32 ttattaata 48
IGKV1-35 P   X71890 tgcagctgtgcccag 17 tgatttgcat 30 ttattaatt 46
IGKV1-37 F IGKV1-37*01 X59316 cgcagctgtgcccag 17 tgatttgcat 32 ttcttaaca 46
IGKV1-39 F IGKV1-39*01 X59315 tgcagctgtgctcag 21 tgatttgcat 31 ttttttatg 46
P IGKV1-39*02 X59318 tgcagctgtgctcag 17 tgatttgcat 31 ttttttata 46
IGKV1D-8 F IGKV1D-8*01 Z00008 tgcagctgtgcccag 17 tcatttgcat 32 ttattaata 46
F IGKV1D-8*01 X72819     tcatttgcat 33 ttattaata 46
IGKV1D-12 F IGKV1D-12*01 X17263 tgcagctgcgcccag 17 tcatttgcat 32 ttattaaca 46
IGKV1D-13 ORF IGKV1D-13*01 X17262 tgcagctgtgtccag 16 tcatttgcat 32 ttcttaata 46
IGKV1D-16 F IGKV1D-16*01 X92329 tgcagctgtgcccag 17 tcatttgcat 32 ttattaata 46
F IGKV1D-16*01 K01323 tgcagctgtgcccag 17 tcatttgcat 32 ttattaata 46
F IGKV1D-16*02 V00558 tgcagctgtgcccag 17 tcatttgcat 32 ttattaata 46
(V00558/J00246)
F IGKV1D-16*02 K01322 tgcagctgtgcccag 17 tcatttgcat 32 ttattaata 46
F IGKV1D-16*02 K01324 tgcagctgtgcccag 17 tcatttgcat 32 ttattaata 46
IGKV1D-17 F IGKV1D-17*01 X63392 tgcagctgcgcccag 17 tcatttgcat 32 ttattaata 46
IGKV1D-22 P   X71887 tgcagctgtgcccag 17 tgatttgcat 32 ttcttaata 46
IGKV1D-27 P   Z00004 tgcagctgtg. . . . . 1 agatttgcat 33 ttatcaata 46
IGKV1D-32 P   X71896 tgcagataaagtcat 14 aaattttcat 32 ttgtacaca 46
IGKV1D-33 F IGKV1D-33*01 M64855 tgcagctgtgcccag 17 tgatttgcat 32 ttattaata 46
IGKV1D-35 P   X71894 . . . . . . .gtgcccag 17 tgatttgcat 30 ttattaatt 46
IGKV1D-37 F IGKV1D-37*01 X71893 cgcagctgtgcccag 17 tgatttgcat 32 ttcttaaca 46
IGKV1D-42 ORF IGKV1D-42*01 X72816 cgcagctgtatccag 17 cgttttgctt 32 ttcttaata 45
IGKV1D-43 F IGKV1D-43*01 X72817 atcccctgtgcccag 17 taatttgcat 32 ttattaatg 46
F IGKV1D-43*01 X72818     taatttgcat 32 ttattaatg 47
2 IGKV2-4 P   X72814 tggatatttcttcac 16 ggatttgcat 38 ataaaa 55
IGKV2-10 P   Z00012     ggatttgcat 37 acgaaa 54
IGKV2-14 P   X72810 tggctctttccaccc 16 ggatttgcat 38 ataaaa 55
IGKV2-18 P   X63400 tggctctttccaccc 16 ggatttgcat 38 ataaaa 55
IGKV2-23 P   X71885 tggctctttccacac 16 ggatgtgcat 38 agtaaa 55
IGKV2-24 F IGKV2-24*01 X12684 atgttatttctacac 16 ggatttgcat 38 ataaaa 55
IGKV2-26 P   X71884 tgttgcgcttagcat 15 ggatttgcat 38 ataaaa 56
IGKV2-28 F IGKV2-28*01 X63397 tgactctttccacac 16 ggatttgcat 38 ataaaa 55
IGKV2-29 P IGKV2-29*01 X63396 tggctctttccacac 16 tgatttgcat 38 ataaaa 55
F IGKV2-29*02 U41645 tggctctttccacac 16 tgatttgcat 38 ataaaa 55
IGKV2-30 F IGKV2-30*01 X63403 tggctctttccaccc 16 tgatttgcat 37 ataaaa 55
IGKV2-40 F IGKV2-40*01 X59314 caaccttttccacac 16 tgatttgcat 40 ataaaa 56
IGKV2D-10 P   X17265     ggatttgcat 37 ataaaa 55
IGKV2D-14 P   X72811 tggctctttccaccc 16 ggatttgcat 38 ataaaa 55
IGKV2D-18 P   X63395 tggctctttccaccc 16 ggatttgcat 38 ataaaa 55
IGKV2D-23 P   X71887 tggctctttccacac 16 ggatgtgcat 38 agaaaa 55
IGKV2D-24 ORF IGKV2D-24*01 X63401 atgttatttctacac 16 ggatttgcat 38 ataaaa 55
IGKV2D-26 P   X12689     ggatttgcat 37 ataaaa 56
IGKV2D-28 F IGKV2D-28*01 X12691 tgactctttccacac 16 ggatttgcat 37 ataaaa 55
IGKV2D-29 F IGKV2D-29*01 M31952 tggctctttccacac 16 tgatttgcat 38 ataaaa 55
F IGKV2D-29*02 U41643 tggctctttccacac 16 tgatttgcat 38 ataaaa 55
F IGKV2D-29*02 U41644 tggctctttccacac 16 tgatttgcat 38 ataaaa 55
IGKV2D-30 F IGKV2D-30*01 X63402 tggctctttccaccc 16 tgatttgcat 37 ataaaa 55
IGKV2D-40 F IGKV2D-40*01 X59311 caaccttttccacac 16 tgatttgcat 40 ataaaa 56
3 IGKV3-7 ORF IGKV3-7*01 X02725 tgcagctggaagctc 14 tgctttgcat 32 atatcaat 53
ORF IGKV3-7*02 X72812 tgcagctggaagctc 14 tgctttgcat 32 atatcaat 53
ORF IGKV3-7*03 K02769 tgcagctggaagctc 14 tgctttgcat 32 atatcaat 53
IGKV3-11 F IGKV3-11*01 X01668 tgcagctggaagctc 14 tgctttgcat 32 atatcaat 53
F IGKV3-11*02 K02768 tgcagctggaagctc 14 tgctttgcat 32 atatcaat 53
IGKV3-15 F IGKV3-15*01 M23090 tgcagctgaaagctc 15 tgctttgcat 32 atatcaat 53
IGKV3-20 F IGKV3-20*01 M15038 tgcagctgcaagccc 15 tgctttgcat 32 atatcaat 53
F IGKV3-20*01 X12686     tgctttgcat 32 atatcaat 53
IGKV3-25 P   X06583 ttctaatgtcactaa 5 aactttgcat 34 atatttat 64
IGKV3-31 P   X71883 tgcagtttcgaagcc 15 tgttatgcat 32 atatcaat 51
IGKV3-34 P   X71891 tgcagctggaagccc 15 tactttgcat 31 atatcaat 53
IGKV3D-7 F IGKV3D-7*01 X72820 tgcagctggaagccc 15 tgctttgcat 32 atatcaat 45
IGKV3D-11 F IGKV3D-11*01 X17264         atatcaat 53
IGKV3D-15 F IGKV3D-15*01 M23089 tgcagctggaagctc 15 tgctttgcat 32 atatcaat 53
F IGKV3D-15*01 X72815         atatcaat 53
F IGKV3D-15*01 M23088 tgcagctggaagctc 15 tgctttgcat 32 atatcaat 53
P IGKV3D-15*02 M23091 tgcagctggaagctc 15 tgctttgcat 32 atatcaat 53
IGKV3D-20 F IGKV3D-20*01 M14507 tgaagctggaagccc 18 tgctttgcat 32 atatcaat 53
F IGKV3D-20*01 X12687     tgctttgcat 32 atatcaat 53
IGKV3D-25 P   X71886 ttctaatgtcactaa 5 aactttgcat 34 atatttat 64
IGKV3D-31 P   X71896 tgcagtttcgaagcc 15 tgttatgcat 32 atatcaat 51
IGKV3D-34 P   X71895 tgcagctggaagccc 15 tactttgcat 31 atatcaat 53
4 IGKV4-1 F IGKV4-1*01 AF017732 tggctcttgatttac 55 gtttttgcat 32 ttttataaa 52
F IGKV4-1*01 Z00023     . . . . . .gcat 33 ttttataaa 52
5 IGKV5-2 F IGKV5-2*01 X02485 tgcacagctgtgaag 81 taatttgcat 38 ataaaat 57
6 IGKV6-21 ORF IGKV6-21*01 X63399 tgcaggtgccagcag 91 taatttgcat 44 ttaaaa 55
IGKV6D-21 ORF IGKV6D-21*01 X12683 tgcaggtgccagcag 91 taatttgcat 44 ttaaaa 55
ORF IGKV6D-21*01 M27750     taatttgcat 44 ttaaaa 55
IGKV6D-41 ORF IGKV6D-41*01 M27751 tgcaggtgccagcag 90 taatttgcat 44 ttataa 53
ORF IGKV6D-41*01 M27751     taatttgcat 44 ttataa 53
7 IGKV7-3 P   X12682 agcaggtgtcccctt 27 tgatttgcat 41 ttaaa 51
n.d.(4) n.d.(4)     J00247 tgcagctgtgctcag 17 tgatttgcct 32 tttttata 52

IMGT notes:
(1) Dots or empty cells indicate partial or absent motifs respectively, due to partial sequences.
(2) The E-Box, if present, is shown in bold.
(3) The OCTAMER is shown in bold.
(4) n.d. not defined. Partial V-GENE sequence: only the promoter sequence is known, the three last nucleotides in 3' being the INIT-CODON ATG.


Created: 26/10/1999
Last updated: Friday, 22-Sep-2023 18:31:11 CEST
Author: Loubna Tazi